Roseanne/Awesome

"Roseanne: Well, what did he say? Dan: Mostly "Ow, ow, my head.""
 * Roseanne and Dan have just found out that Rosanne's sister, Jackie, was being physically abused by her boyfriend. As Rosanne takes Jackie to the hospital, Dan just stands there, looking very pissed... before grabbing his coat and stomping out the door, clearly out for blood. Half the studio audience did the standard dramatic "Ohhh!" The other half applauded.

"Roseanne: You just make sure you never come near Jackie again, because to get to her, you'll have to get through me, and I'm a lot more dangerous than Dan. I own a loose meat restaurant; I know what to do with the body."
 * A better moment is later on when the police come to arrest Dan after Fisher calls the police afterwards. Dan insists on going along quietly.
 * Also, from the second half of the two parter of the above episode, Roseanne's final words to Jackie's boyfriend, Fisher:

"Roseanne: Mark, remember all those times you screwed up? This isn't one of them."
 * The episode "Roseambo". Roseanne kicking some serious terrorist ass was awesome enough, but when one of the remaining guys snuck through the window and tried to attack, Mark immediately whirls around and shoves the guy through an open window.