One of the Seven Signs of the Apocalypse

Something of a Stock Phrase, this is a common humorous hyperbole used to emphasize how unlikely a given event or action is in the current context, such as Out-of-Character is Serious Business Alternately, it can be used to suggest that something is so awful that it must be a sign of the impending end of the world, usually with a knowing wink at the exaggeration. It is often used to lampshade when the Dumbass Has a Point.

In use it takes either a declarative form ("X is One of the Seven Signs of the Apocalypse.") or an interrogative ("Isn't X One of the Seven Signs of the Apocalypse?").

The Trope Namer (but not an example), of course, is The Bible, and references the Seven seals which are opened in Chapters 5-8 of the Book of Revelation; as each is opened a judgment is released or an apocalyptic event occurs, which are the actual signs.

Note that this trope is not about the serious use or identification of current or historical events as literal signs of an (or the) Apocalypse, or speculation on the same. It is only about amusing hyperbole.

This trope does include any other phrase with similar meaning which is used in the same manner, such as " -- the end times are clearly here", or "does anyone see four horsemen riding up?"

Not to be confused with The End Is Nigh or Signs of the End Times. If it's someone saying the end is nigh if this thing happens, and then it does, see Cue the Flying Pigs.

Anime and Manga
"Kenshin: Kaoru cooking? Is it a sign of the apocalypse?"
 * Rurouni Kenshin

Fan Works
"Dawn put on a smile and held out her hand to help him to his feet. "Hi Dean. You're the first to arrive." Dean smiled back, and started to brush the soot from his clothes. "Of course. Couldn't have the Weasleys show up on time. That's one of the signs of the apocalypse." Buffy smiled at him. “"Actually, no... I think I've seen most of the signs, and that's not one of them.""
 * Late in Harry Potter and the Key of Dagon, a Harry Potter/Buffy the Vampire Slayer crossover fic by "DonSample", there is this moment:

Film
"Don't be ridiculous, it's not one of the signs of the apocalypse when he starts quoting Judy Garland. When he starts singing like Ethel Merman, then you've gotta worry."
 * Played with in Summerslam

"Mike, in a relationship? Isn't that one of the signs of the Apocalypse?"
 * Buying the Cow

Literature
""Well, hell," Tod hooted. "Allen disagrees with you, Maya. Isn't that one of the seven signs of the apocalypse?""
 * In Zombie Zero: The First Zombie by J.K. Norry, there is the following passage:

"While most people look toward a nuclear Iran or melting ice caps to get a heads-up on the end of the world, I train my eye on the programming of the Hallmark Channel. The more modern the time frame and the more cynical the casting, the closer we are to the end of the world. For example, if you see a Hallmark movie entitled The Search for Mrs. Santa starring Liza Minnelli and Simon Cowell, consider it one of the seven signs of the Apocalypse."
 * The Dangerous Animals Club by Stephan Tobolowsky has this comment at the beginning of its 22nd chapter:

""Did Mama just hand me a cup of human blood and then make a joke about a horror movie?" I asked Jenny, who nodded, all astonishment. "Doesn't the Bible list that as one of the seven signs of the Apocalypse?" "Well, not in the King James version," Jenny said."
 * In Nice Girls Don't Bite Their Neighbors by Molly Harper:

"I started to get annoyed, but was struck by the disturbing thought that if I did, I would be coming down on the same side of the situation as Charity, which might be one of the signs of the apocalypse."
 * The Dresden Files book Proven Guilty. Harry thinks:

Live-Action Television
"Judy: [to Christina] Hey, you're falling in love, it's not one of the seven signs of the apocalypse... Is it?"
 * In episode 10 of the 2005 FOX series Point Pleasant, there was this line of dialogue:

"Miss Fine and Miss Babcock walking arm in arm. Isn't that one of the biblical signs of the apocalypse?"
 * The Nanny

"Oh, sh*t. Sean Garrity readin' a book. That's the first sign of the apocalypse."
 * Rescue Me episode "Bitch".

"My God, no more attention. This is like one of the signs of the Apocalypse."
 * Puppets Who Kill episode "Dash the Greeter"

"Lois Lane: Clark Kent and Karaoke - isn't that a sign of the Apokolips?"
 * Smallville, unwittingly making a Pun:

"Alex: She's right. I'm wrong, and Mallory's right. The world is ending!"
 * In the final season of Buffy the Vampire Slayer they point to the band playing in the Bronze (Nerf Herder, a song from whom also provided the theme tune throughout the series) as a sign of the Apocalypse. At the same time as a lot of rather more conventional signs of the apocalypse are occurring.
 * Family Ties:

Newspaper Comics
"Rat: What is true happiness?...How does a dumb pig like you answer a question like that? Pig: I think happiness is finding an extra couple of french fries at the bottom of the bag. Rat: ...Pig made sense. The apocalypse is upon us."
 * From Pearls Before Swine.

Web Comics
"Chuck: Does this seem like a particularly awkward silence? James: Dude, Miriam's not saying anything. It's the end times, man."
 * From Out There, this moment when even Motor Mouth Miriam has nothing to say:

""But it can't be the Apocalypse today, the Mayan calendar says...""
 * From Penny and Aggie, when the two leads put their "Betty and Veronica" rivalry behind them and become friends:

Web Original
"Rumor has it that Jersey Shore's Snooki is preggers. Since this is clearly one of the seven signs of the Apocalypse, we’ll keep this short. How long before we see this magazine cover?"
 * A 2007 essay at Humorpress.com explicitly proclaims The Bachelor one of the seven signs.
 * Mad Magazine's website has a page about a 2012 rumor that Snooki from Jersey Shore was pregnant. It introduces a parody of a Vanity Fair cover with

"If the show had started any later, [Vogue editor Anna Wintour] might have started posing with people and delivering phone-cam shout-outs to their mothers. We believe that’s one of the seven signs of the apocalypse, so keep an eye out for it. The world can’t end before Fashion Week does."
 * A 2010 article about a fashion show at thecut.com, a spinoff of NYMag.com, ends with

"Taco Bell Is Making a Taco Shell Out of Fried Chicken Isn't this one of the seven signs of the apocalypse?"
 * And Maxim's website actually uses the phrase in the headline for an article:

"We've checked, and it's not actually one of the seven signs of the apocalypse (but we're pretty sure that was just an oversight by the Bible's authors. BECAUSE LOOK AT THEM)."
 * Comedy Central UK has an article on its website about a Japanese product -- flesh-colored tights with pre-printed toenail polish on them -- in which they say:

Web Video

 * In episode 3 of Bad Obsession Motorsport's Project Binky!, narrator Richard says, "I'm sure that Nik not using a grinder when the opportunity presents itself is one of the seven signs of the Apocalypse."

Western Animation
"Hordak: The end of the world is upon us, Grizzlor has had an idea!"
 * Humorously used in an episode of The Fairly OddParents. Timmy gets an "A", at which the other students panic, thinking it's the end of the world since he's normally a terrible student.
 * She-Ra: Princess of Power

""These are the end times.""
 * Justice League Unlimited, in the grand finale, when Flash learns that the Martian Manhunter is married: