Oniisama e.../Nightmare Fuel

For a very melodramatic shoujo originally from The Seventies, the animated version of Oniisama E (from 1991) gives some REALLY creepy scenes.

"Rei: I waited. Forever. Forever."
 * 's apartment, which only has mirrors and Creepy Dolls aside of two/three furniture pieces. And this is without counting ... Room Full of Crazy, indeed. Doubles as a Tear Jerker, considering the circumstances in which we find out about it.
 * Also, the scene in which  Of course , but it was still SO FUCKING CREEPY.
 * Nanako has a nightmare in which Fukiko picks up the kenzan she dropped onto Rei's hand and maims her with it. We're never shown explicity what she does, but Nanako does give a chilling scream, clutching at her eyes.
 * It's even creepier in the anime. (around 2:15)
 * The scene where Rei, after being overloaded on drugs and with a high fever, mistakes Nanako for Fukiko and  Then turns into a Tear Jerker
 * In the manga, Fukiko is very good at pulling Nightmare Faces.
 * While comparatively mild, after Nanako runs out of her birthday party, Mariko grows depressed and refuses to eat anything. Kaoru notices and tries to cheer her up, but Mariko angrily rejects her, saying "What good is health? Who cares about health!". The usually level-headed Kaoru becomes so infuriated that she lifts her into the air, shaking her and screaming into her face.
 * In episode 13, after we just hear Mariko telling Nanako and Tomoko a tale of Star-Crossed Lovers committing suicide, Fukiko hears music playing and investigates. While first seeing nothing, we then see a shot of Rei appearing out of nowhere, her silhouette pressed against the window and looking utterly terrifying. And when we do see her expression, she looks half-dead. That same scene ends with Rei laughing hysterically and jumping out a window.