Cookie Clicker

Cookie Clicker is an Idle Game by Orteil and Opti.

Click the big cookie, get a cookie. Click it again, get another cookie. Get enough and you can spend cookies on more cursors to click the cookie for you. A few hours of upgrades later, the grandmas that you hired to work in your cookie factory are doing occult rituals in the bingo parlor and warping time and space just to make billions of cookies per second for you.

"defective alchemy lab shut down, found to convert cookies to useless gold."
 * Cursed with Awesome: Wrinklers appear to reduce your production by nibbling on the big cookie, reducing production to 50% once all ten have attached. But they work as a team to keep your facilities clean, and once they get fattened up, you can harvest the crumbs that they have nibbled for what amounts to a 600% multiplier.
 * Defictionalization: Of the game show "Hit The Buzzer, Win A Cookie" from the Garfield and Friends episode "Astrocat".
 * Difficult but Awesome: If you enter Christmas season and carefully plan how long you wait before clicking the red cookies, you can occasionally score an "Eldeer" (reindeer during Elder Frenzy), which is worth nearly a day's worth of production.
 * Granny Classic: The standard grandma and the "Grandmas' grandmas" associated with time machines.
 * Number of the Beast: The initial price of the Portal and the prices of its upgrades have a 666 theme. This sort of implies that the "Cookieverse" is hell.
 * Save Scumming: Saving and reloading the game to diminish bad effects from red cookies.
 * The Wiki Rule: Cookie Clicker Wiki on Wikia
 * Worthless Yellow Rocks: Subverted with the alchemy labs. Everyone thinks gold is worthless.