Brain Powerd

One of the most bizarre anime by Yoshiyuki Tomino, Brain Powerd takes place in a future Earth ravaged by earthquakes and flood, all of which are the result of the activity of a mysterious sentient alien spacecraft called Orphan, buried in the depths of the Pacific Ocean and home to a group of scientists and researchers known to the world as Reclaimers. Orphan's true objective is to eventually rise from the ocean and start a new journey into space... which, however, would cause The End of the World As We Know It, since Orphan needs to feed on the organic energy of all living beings to sustain itself in its journey. The Reclaimers do not seem to care much, though, and are willing to go through with Orphan's plans, seeing themselves as Orphan's chosen ones that will become the seeds of a new humanity. To fulfill their plans, Reclaimers make use of Empathic Weapons, living organic mechas known as Antibodies or Gran Chers, and endlessly search for the Plates from which they originate, in order to swell their numbers. However, not all is lost, since the Novice Noah, a group of Antibody pilots using the Brain Powerd, infant forms of Gran Cher, rises to stop the Reclaimers' plans.

The series mostly follows the adventures of Yuu Isami, a renegade Reclaimer seeking freedom from Orphan's oppressive environment and his family's aloofness, and Hime Utsumiya, an orphaned girl who accidentally stumbles upon a Plate under Revival process and finds her own Brain Powerd, which she almost immediately makes friends with. After their first encounter results in a battle, the two teenagers find themselves reunited when Yuu escapes Orphan and a group of Reclaimers gunning for his blood; this is only the start of an adventure rife with surprising reveals, well-developed characters and government conspiracies, which will allow Yuu and Hime to understand more about themselves, the world around them and the complexities of human feelings and mutual relationships.

Brain Powerd focuses quite a bit more on Character Development than Humongous Mecha action compared to many other anime of this genre.

The series is also notable for being Yoshiyuki Tomino & Mamoru Nagano's first collaboration in over a decade. They had allegedly had a falling out during the production of Mobile Suit Zeta Gundam over a woman, probably seiyuu Maria Kawamura who eventually became Nagano's wife.

The show is basically Tomino's take on Neon Genesis Evangelion.

This series provides examples of:

 * Action Girl (Hime. Higgins and Kanan also count.)
 * Aloof Big Brother (Played straight and subverted: Quincy is an Aloof Big Sister (to Yuu) when she's the fanatical leader of the Antibody attack squads, but a warm and caring individual when showing her true personality)
 * Anti Villain (The Reclaimers aren't really bad guys, with the exception of Igor. They're mostly people with a tragic past who were drawn to Orphan in an attempt to find a place where they could belong and ease their suffering. Come to think of it, is very much an Anti Villain.
 * Arab Oil Sheikh (Mohammed, assumedly.)
 * Big Screwed Up Family (The Isami and Glenn families. Not really that big, but most definitely screwed up.)
 * Broken Bird (Sheila. )
 * Calling the Old Man Out (Both Yuu and Jonathan do this. )
 * Character Development
 * Chessmaster
 * Cool Ship (The Novus Noah)
 * Dark Action Girl (Quincy and Sheila)
 * Deadly Upgrade (the Baronz, an evolved form of Antibody who results from the revival of a Gran Cher. )
 * Dysfunction Junction (Pretty much everyone except Hime and the children have problems with their life. Mostly Freudian.)
 * Eagle Land (The United States at one point attempts to claim Orphan for themselves, going so far as to call it their "51st State." )
 * Even Bad Men Love Their Mamas
 * Everybody Lives (The death count for this show, apart from backstories, is pretty much nil. Shocking considering that Tomino worked on it.)
 * Face Heel Turn
 * Fake Out Spoiler Opening: (The opening animation is filled with naked girls and maybe three shots of the Humongous Mecha, along with a song about a woman dreaming of endlessly being made love to. The series itself barely has shirtless males. On the other hand, it does show all of the female pilots, regardless of when they appear in the series.)
 * Fan Nickname (Jonathan = Johnny Boy; Quincy = DTR Girl, short for 'Deaf To Reason Girl')
 * First Kiss (Hime got hers in a manner she probably didn't expect at all...)
 * Freudian Excuse (Everyone has one in this series)
 * Gentle Giant (Nanga)
 * Giant Robot Hands Save Lives (all over the place...)
 * Heel Face Turn (Kanan. )
 * Heroes Want Redheads
 * Heroic Sacrifice
 * Humongous Mecha
 * I Banged Your Mom
 * Ill Girl (Nelly. Also, )
 * Improbable Age (Kant is a world authority of Organic energy and the Vital Net... and he's only 10 years old!)
 * Ineffectual Loner (Yuu at the beginning)
 * Jerkass (Jonathan)
 * Jerk With a Heart of Gold (Nakki Guys. Some fans refer to him as "the anti-Jonathan")
 * Karma Houdini (Debatable. )
 * Kick the Dog (We did say Jonathan is a jerkass, right?)
 * To be fair, he does have a Pet the Dog moment with Kumazo at the end of episode 9. Even Jonathan has standards
 * Killed Off for Real
 * Kill Em All
 * Love Makes You Evil
 * Mad Scientist (Yuu's parents show traces of this)
 * Mama Bear (Probably the most twisted version of this ever )
 * Mask Power (Baron Maximillian, )
 * Mildly Military: (The Novis Noah doesn't exactly have the strictest discipline)
 * Nipple and Dimed (Pretty much the entire OP.)
 * Not Quite Dead
 * Not So Different (Higgins and Sheila are more alike than either would care to admit...)
 * Official Couple (Quite a few. )
 * Parental Abandonment (Pretty much this anime's breath, bread and water!)
 * Pigeonholed Voice Actor (Quincy is played by Watanabe Kumiko, who usually plays very mean characters if the said character is a girl (but usually good if the said character is boy). Don't believe it? Look at another bitch in Tomino's other work)
 * Rousseau Was Right
 * Screw Destiny ("We make our own fate!", says Sheila to Higgins.)
 * Shout Out (mostly to Aura Battler Dunbine, one of Tomino's earlier works)
 * Slap Slap Kiss (Yuu and Hime)
 * Sliding Scale of Idealism Versus Cynicism (Definitely on the idealistic side of it)
 * Smug Snake (Jonathan)
 * Split Personality (Quincy Issa. Or is it Iiko Isami? Oh, well...)
 * The Social Darwinist (the Reclaimers)
 * Super Robot Wars (Has appeared in J and Alpha 2)
 * Another Centurys Episode (Appears in the first three games, but only gets plot in the first two.)
 * (Pre)-Teen Genius (Kant)
 * The End of the World As We Know It (What will happen if Orphan leaves the atmosphere)
 * The Messiah (Both Hime and Nelly)
 * The Power of Friendship
 * The Power of Love
 * The Reveal (So, so many of these...)
 * Tsundere (Definitely Hime. Also, Higgins, who is an aloof-warm type)
 * Well Intentioned Extremist
 * Wig Dress Accent (Taken to an extreme with
 * With Great Power Comes Great Insanity (Jonathan, Quincy and Baron Maximillian are much more unhinged when piloting a Baronz. Earlier on, Igor also plays this trope)