CUTE×GUY

Sumi Takaoka is a generically cute girl with a problem, she has a crush on guy - Mitsuru Sudou - who rumour says prefers buxom and mature and sexy types... everything she isn't. However, she thinks may just be in luck as her Mad Scientist father has just invented a medicine that he has promised will give her the mature and sexy attributes she desires. So, heart pounding as it it always does when she's near Misturu she downs the formula in once gulp...

...and it transforms her into a mature looking, tall, and sexy... man! And it will do so now every time her heart races as that was her condition when she drank the medicine and she'll stay male each time she does until the effects have worn off two hours later. On top of all this her father is not only out of the country but also deeply unhelpful whenever she contacts him as he's more interested in using her as a lab rat for his new medicine (designed to replace sex change operations) and her mother who is a stylist just wants to use her as male model. Also she finds herself aggressively lusted after by the vampish school nurse. On the plus side Misturu looks up to her male self (who she seems to present a more confident front as than she does as herself) and wants to be friends, figuring she'll get to know him better this way she decides to become his mentor, aquiring the name Jun Tadano by accident.

Soon other gender benders show up, mostly male-to-female, who have either been similarly conned by her father, or in one case are related to his biggest rival - all of them with different triggers and one of whom who develops a crush on Sumi. Thus commencing the (as yet not yet officially translated) manga Cute X Guy by Makoto Tateno.

This program provides examples of:

 * Abusive Parents Sumi and Shizuka's fathers force gender dysphoria on their children just to use them as lab rats, and Sumi's mother is more interested in making her daughter dress up as a male model as she wanted a boy anyway.
 * Attractive Bent Gender Sumi is your cute but averagely so looking shojo lead. Jun on the other hand is tall, toned, and looks older than his years in a good way. Sumi also carries herself better as Jun and seems effortless cool and charming - then you cut to a (still male) Jun freaking out and wondering why just as he's running off somewhere.
 * Gender Bender
 * Gender Bender Friendship the main premise for the plot, at least until other gender benders show up
 * First Law of Gender Bending despite the main lead being a rare example of a female to male gender bent character who has it as a recurring problem rather than a one off, most of the other gender bent people she meets are male to female. The only other female to male she meets is cured fairly quickly and forgets it ever happened to her.
 * Hospital Hottie Kyoko-sensei, blonde, buxom, sultry and a (in this case school) nurse
 * Hot for Student Kyoko-sensei the school nurse comes on very heavily to Jun even though she initially thinks he is a (older looking) student.
 * Hot for Teacher Kyoko-sensei is very popular amongst the male students at Sumi's school
 * Mad Scientist Sumi's father, and his rival the father of Nishizawa Shizuka
 * Mistaken for Gay whenever Jun is out with Mitsuru giving him 'manliness tips' due to the fact that they look like the archetypical Seme and Uke, they keep attracting crowds of fujoshi
 * Sue Donym this how Jun end's up with his surname, the name Jun is a different reading of the same Kanji as Sumi but "Tadano" came into play when Kyoko-sensei asked for Jun's full name again got "Ta da no Jun!" or "It's just Jun!" and misheard it as "Tadano Jun".
 * The Vamp Kyoko-sensei the school nurse, not only is beloved by the schools male population (most of them anyway) but almost forces herself of Jun/male Sumi until she gets the brush off.
 * Yaoi Fangirl small crowds of them flock to Jun and Mitsuru whenever they are out together as the two really look (and act) the part of a Seme and Uke
 * Yaoi Fangirl small crowds of them flock to Jun and Mitsuru whenever they are out together as the two really look (and act) the part of a Seme and Uke