Lucky Star/Funny

"Yutaka: "Oh, Tamura-san!" (with the most innocent smile on her face) "What does yaoi mean?"
 * From Lucky Star episode 19:

Hiyori: *reacts in shock* "That...depends on which one you mean!""

"Kagami: What's with the (bleep) D-like driving!?"
 * The ED theme for the same episode: "SUPPON! SUPPON! SUPPON!" ("NAKED! NAKED! NAKED!")
 * The other best moment in the series, from episode 12, also involves yaoi. "Gauron and Sousuke are..."
 * The dub line for Kagami on this sounds dirtier.
 * Link.
 * Episode 5 end credits. Konata does Dragonball Z. SPARKY!
 * The irony:
 * Ladies and Gentlemen, MEITO ANIZAWA and HIYORI TAMURA
 * Also FEINTO DESHITA,AAAAAAAAAAHHHHHHHH!!!!
 * The Initial D Parody on episode 6.

"Minoru: WERUCAM TU AIDAHOOOO!"
 * Or how about in the same episode when, after Tsukasa puts a seashell to her ear and imagines she's floating in the ocean, a crab pops out, prompting a very reasonable scream and making her run to her sister?
 * Patty describing "Otome Road" and Yutaka's Imagine Spot.
 * Of Minoru Shiraishi's live action endings, the end of Kaorin's Theme and Ore no Wasuremono as a whole probably take the cake. And Koi no Minoru Densetsu once learning the full version is a SPEED METAL REMIX of the song it's based off of.
 * I prefer how he starts a different ending:

"Konata: Hmm... if this dude's the main one... then the little ones around him... are all the Options! Kagami: You ever hear of divine punishment?"
 * Another favorite is in the "Wawawawasuremono..." ending, which includes Shiraishi singing next to a random couple (who seem to be trying their best to ignore him), and a subtitle pops up pointing at them which reads: "Random couple who readily agreed to be in this video."
 * The New Years episode was memorable because out of the blue, Tsukasa says some odd dialogue ("Rice cake goes wee!" and "Cheesecake?").
 * After Konata's famous "a flat chest is a status symbol" scene, Tsukasa replies "I guess I'm safe too".
 * In episode 21, where they go to the Daibutsu in Nara, and Konata calls the figures around the main statue "the options".

"Konata: But doujins are meant to be read...
 * The OVA:
 * "Tsukasa, press enter."
 * "I want to *a@%&! with Konata."
 * Tsukasa's moment of volleyball glory.
 * "Hitting the net hurts..."
 * "I seem to have become a treefrog."
 * Turning Kagami into Miku!
 * "Don't touch me~"
 * Hiyori's instantaneous Scary Shiny Glasses when Konata gives Minami a strange solution for her problem, and the ensuing conversation about Doujins early in chapter 23.

Hiyori: Not by the normal people! Please have mercy!"

"Fantasy!Yutaka: Minami-chan? (a little deeper) Minami-chan? (a LOT deeper) MINAMI-CHAAAAAAN!"
 * How come Hiyori's fantasy of Yutaka growing up isn't mentioned. It's THE funniest moment in the anime, in episode 19.

"Konata: Yeah, and you're already bitten."
 * Soujiro telling a mosquito "You are already dead.".


 * Tsukasa feeds deer. It's really really cute until about :17, where the most amazing deer ever happens.
 * STURONGGA!!!!
 * Izumi's Timotei. Hell, in the English version, she even says 'Bitchin!'
 * A blink-and-you'll-miss-it moment in the MMORPG part of the OVA: When Konata and co. do a team victory pose, a random male character joins in on the far right, and then just walks away without anyone noticing.
 * Konata's "I'M A SENIOR" in episode 18.