I Can't Believe It's Not Heroin!

""Hey, kid! Wanna smoke some candy with me?""

- Blue Laser Commander, Cheat Commandos

Sometimes a completely mundane substance is treated as if it had psychedelic effects and was highly addictive. Compare:
 * Alien Catnip, where mundane substances really are drugs to someone due to Bizarre Alien Biology;
 * Drunk On Milk, for drunkenness;
 * Evil Tastes Good, which might involve a completely mundane substance like Turkish Delight magically being made addictive;
 * Frothy Mugs of Water, where this happens because, originally, it was heroin, but was censored to a more G-Rated Drug;
 * Fantastic Drug, when the "drug" doesn't even exist in reality;
 * Addictive Magic: Magic is a drug.
 * The Dark Side: Evil is a drug.
 * G-Rated Drug, where a Moral Guardian approved "soft" drug's effects are vastly exaggerated to fit a storyline that would otherwise require harder drugs to work.
 * High On Catnip - when a catlike character ingests catnip
 * Intoxication Ensues, where otherwise straightlaced characters accidentally ingest a drug, or too much of their prescribed meds, and Hilarity Ensues;
 * Mushroom Samba, where characters "trip" on hallucinogens of some kind without meaning to;
 * Toad Licking, where a character gets high by licking toads.

Advertising
""Ridiculous Lucky Captain Rabbit King! Lucky Captain Rabbit King Nuggets are for the youth!""
 * Most breakfast cereals, if their commercials were taken at face value, would belong on the controlled substances list. They are depicted as astonishingly addictive and people will go to great lengths to obtain them. (Some of this may be a result of marketing to children, who have to beg or bargain with their parents rather than simply going down to the store and buying a box for themselves.)
 * Parodied and almost justified in an episode of The Powerpuff Girls, where a box of cereal actually contains a huge (stolen) diamond, and the thief will do anything to get it back... including dressing up as a cereal mascot and trying all the usual tricks, only to be thwarted again and again.


 * An American Public Service Announcement commercial about drug use has kids "sloming" (Sticking Leeches On Myself...ing) as an allegory for marijuana use. (Because obviously, no one would ever enjoy getting high if it weren't for peer pressure.)
 * A similar UK anti-smoking ad has "blue sticks".
 * A UK advert for "Burger King" featuring The Burger King has his burgers being treated this way, with the King acting as a man's imaginary friend and holding a burger all throughout his day, until he manages to eat one at Burger King.

Anime & Manga

 * Parodied in Welcome to The NHK, where Misaki, jealous of Satou's love for an older, hard drug-using woman, tries to overdose... on mints.
 * Like so many things in this series, it manages to be incredibly tragic and absolutely hilarious at the same time.
 * In Kogepan the anthropomorphic breads get drunk out of milk.
 * If Belldandy drinks even just a sip of cola, she gets drunk. On the other hand, real alcohol has no effect on her.
 * The American dub of Digimon has one episode wherein two of the main characters get an enemy red-faced and drunk on brown-bottled "soda" so they can sneak past him when he passes out. It is explained that "the bubbles go right to his head."

Comic Books
"Mary Violet: AAAGH! The bubbles! The bubbles are exploding in my BRAIN!
 * In the 1960s, Mad Magazine had a comic about a hippie trying to extract bananadine (see Real Life below) from a banana peel.
 * Uncle Ump's Umpty Candy is outlawed in Mega-City One as it's addictive. There's no narcotic in it-- it's just that good.
 * Joan from Amelia Rules creates a drink called Joan's Jet (half ginger ale, half grenadine and a mentos) at Amelias 11-year birthday party. The ensuring sugar rush after she gets one too many fully justifies the name. Apparently it can also cause bad trips:

Joan: Mary Violet! Wait! That's a normal reaction!"


 * There are two Donald Duck stories of which the older about Donald's fixation with soda is a rather obvious parallel to alcoholism, right down to his loved ones staging an intervention, and sending him to rehab. And secret stashes of soda in the house. The newer shows Scrooge McDuck addicted to coffee, now with parallels to drugs.
 * In an older Carl Barks story, Scrooge McDuck is depicted addicted to nutmeg-tea; interestingly, considering the real, drug-like effects of large doses of nutmeg. As a (possibly unintended) Subversion of sorts, he never cuts the habit, but gets a fresh supply of the substance at the end of the story. According to Don Rosa's canon, he still keeps indulging the stuff with the old enthusiasm.

Film

 * Laurel and Hardy manage to get "drunk" via wishful thinking in Blotto, even though their prohibition-era booze has been replaced by a noxious, but non-alcoholic, mixture by Mrs. Hardy.
 * The aliens in District 9 are addicted to cat food.
 * This is a reference to the rather horrible stereotypes about the inhabitants of slums such as the actual location where District 9 was shot.
 * Alternatively, it's because cat food is used as prawn bait; remember how the aliens are called Prawns?
 * The newcomers in Alien Nation get drunk on sour milk.
 * A peach does the job and knocks Sarah into a fever dream in Labyrinth. (A sexy fever dream?)

Literature
""You are a drug dealer. To tiny fairies. For shame.""
 * The Big Chocolate Bar features a ban on chocolates and sweets in a school camp resulting in every single allusion to drugs possible: hopelessly unhealthy students go into catastrophic withdrawal; "dealers" begin making homemade chocolates and selling them on the black market; groups of smugglers transport cases of sweets into the camp, using the limited supply to charge up to twenty dollars per product. Finally, a student robs a general store and overdoses on the stolen confectionery. It's hilarious.
 * The Boy Who Reversed Himself by William Sleator features travel in 4th and 5th dimensions. If one is not careful, one can get flipped around while in the fourth dimension, so that a 'reversed' version of yourself (think, mirror image, with L/D chirality) returns to the normal three dimensional world. The teenage protagonist does just this, and finds that the cafeteria food is much different than expected. The french fries taste like nail polish, but the ketchup...she ends up fairly drunk on reversed ketchup.
 * At one point one of the protagonists even takes some ketchup packets to the high dimension, flips them, then gives them to another kid, and says she'll give him more if he helps her out.
 * Jasper Fforde likes this trope. In the Nursery Crime book The Fourth Bear, the bears have problems with porridge, honey, buns and marmalade (in increasing order of addictiveness). Thursday Next has a sideline smuggling cheese from Wales, and there's a scene in First Among Sequels reminiscent of Pulp Fiction where she meets her contact and tests the product.
 * In The Dresden Files, the Little Folk (pixies) love pizza with a passion that is not rivaled by any in this world. Watching them devour it has been variously compared to Jaws and a school of piranhas. Harry Dresden pays them in pizza and in return they provide him with whatever services he asks of them. As Sanya puts it:


 * In The Underland Chronicles, a certain carnivorous plant subdues its victims by getting them high off its euphoric fumes.
 * In Villain.net,
 * In Harry Turtledove's Worldwar (Literature) series, the spice ginger has an addictive effect on the reptilian Race.

Live Action TV

 * On Being Human, blood is like drugs for vampires.
 * In Wizards of Waverly Place, you'd better think twice before giving an elf chocolate.
 * Almost every single episode from the first season of Smallville treats the Monster of the Week as a metaphor for drug addiction.
 * Bottom, Burglary. Richie ponders that the burglars are maybe looking for drugs, Eddie notes they don't have any - therein lies the problem as the burglars will continue to search in vain 'til sunrise. Thinking of an appeasement strategy, they try to think of the strongest thing throw down the stairs to make them go away. The best Eddie can think of is Lemsip.
 * The Frasier episode "Roe To Perdition" treats caviar as an addiction. Frasier and Niles become dealers (even considering buying inferior caviar and "cutting it with the good stuff"), while Roz turns into a strung-out fish-egg addict.
 * Parodied at the end of the episode where the Caviar smugglers turn out to be  smugglers.
 * Another episode has Niles purchase a brownie stuffed with marijuana, but after a mix up he eats a plain one while his father gets the spiked one. He acts stoned, but is largely confused by his father's odd behavior.
 * Parker Lewis Can't Lose once dealt with video game addiction. In an abrupt about-face, the episode ends with the characters not demonising video games or even the playing of them, but saying what matters is how you approach them.
 * In Freaks and Geeks, all of the Freaks get 'drunk' off of nonalcoholic beer. Lindsay's little brother has switched a keg of alcoholic beer for nonalcoholic beer under the influence (haha) of anti drug assemblies from school.
 * This is Truth in Television though, since the people drinking the nonalcoholic beer don't know it's nonalcoholic, resulting in the placebo effect.
 * In First Wave, Cade literally rubs some salt in Joshua's wounds; he proceeds to get all dreamy about how nice Earth is and give the reasoning for his soon-to-be revealed Heel Face Turn. Cade is shocked at his state of mind, realizing salt is their heroin. In a later episode, we even see a Gua hunting down another in a back alley, where he has been hanging out with human heroin junkies feeding his addiction to salt.
 * Spoofing the immense amount of media coverage Starbucks' three-hour nationwide shutdown received, Stephen Colbert did a segment on The Colbert Report in which he reacts to three hours without coffee by going into severe withdrawal. He physically attacks those around him, digs desperately through garbage cans for old Starbucks cups that he can burn and inhale, and, when Starbucks "finally" reopens, huddling naked in a shower stall and dousing himself in cup after cup of coffee.
 * In a Monty Python's Flying Circus sketch about hoodlum grandmothers, one of them is addicted to crochet. "She can't do without it. Twenty balls of wool a day, sometimes."
 * In 30 Rock, Kenneth the Page "Rides the brown serpent" when a cappuccino machine is introduced to his desk.
 * He also once said that he was "addicted to coke back in my wall street days". Cut to a flashback of him working at a video store (with a Wall Street poster on the wall), drinking a can of Coca-Cola, and giggling like a stoner.
 * Bill's 'lemon sherbet' in the early seasons of The Goodies, even to the extent of a policeman asking what he was on.
 * Possible Trope Namer, The Sketch Show had a brief sketch where a man smuggles heroin through customs in a bag labelled "I Can't Believe It's Not Heroin." It works, although it looks for a moment like it won't. Not only that, but moments earlier the customs officer had assured him that his tub of "I Can't Believe It's Not Butter" was fine.
 * In Malcolm in The Middle, Malcolm's obsession with fixing up a junker he bought is played like a substance addiction. He raids his savings for automotive parts, his grades drop because of all the time he's spending on the car, and his brother holds an intervention, complete with a guy from the AAA.
 * Seinfeld had shower-heads with illegally high pressure.
 * One of the characters in The Legend of Dick and Dom has a one-episode addiction to gingerbread; we don't see her actually intoxicated on it, but she hoards it, denies she has a problem, gets withdrawal symptoms when her friends take her stash away, obsessively hunts for more and finally starts seeing people as giant gingerbread men and dreamily chewing on them.
 * One of the characters in The Legend of Dick and Dom has a one-episode addiction to gingerbread; we don't see her actually intoxicated on it, but she hoards it, denies she has a problem, gets withdrawal symptoms when her friends take her stash away, obsessively hunts for more and finally starts seeing people as giant gingerbread men and dreamily chewing on them.

Music
"It's a game, that's what I tell myself
 * A promotional video for Melissa Lefton's debut album was a parody of Behind The Music and depicted her tragic decline into Sunny Delight orange juice addiction.
 * Josh Ramsey of Marianas Trench is infamous for the insane amounts of Coke Zero, never plain and certainly not diet, that he drinks
 * He is an ex-heroin addict.
 * Potatoes, as outlined in "Addicted to Spuds" (and in its original version, "Addicted to Love", love).
 * An earlier Weird Al example being "Pac-Man".
 * "Animal Forest" by 14 Year Old Girls portrays Animal Crossing this way:

But it has so much play, I think I might need help

I'm always late for class and I got fired too

But every day I'm hooked because there's always something new..."


 * Lemon Demon has a couple songs like this, respectively about crayons and explosives.
 * Sugar Rush by Anthony and Those Other Guys lives on this trope.

Newspaper Comics

 * Bloom County tackled the "War On Drugs" topic with various ways, but one of them was rather silly: "Snorting Dandelions".
 * In Get Fuzzy, Bucky occasionally gets high on catnip.

Video Games
""The Queen may one day lose her taste for peace, but her children will never lose their taste for cheese.""
 * Earthbound. Magic Cake. 'Nuff said.
 * Don't forget the Coffee and Tea the Mr. Saturns and Tenda give you. After all, the Coffee and Tea make you trip out.
 * The genie in King's Quest VI is addicted to mints and acts drunk when he's eaten too many. At the end of the game, you can give the genie.
 * The moai heads in the Sam and Max Freelance Police game "Moai Better Blues" get...well... stoned on basalt.
 * Soda Popinski in Punch Out. A single drop from his bottle causes him to spring up from being knocked down, get red and steamy and release a barrage of uppercuts.
 * Another example of Bowdlerization leading to this; Soda Popinski was originally the Trope Namer for Vodka Drunkenski.
 * In the background fiction of Sword of the Stars, Hivers find cheese intoxicating.


 * Yume Miru Kusuri never states outright what drug your protagonist get doped up with on one route, but it's apparently cocaine, according to the effect it has on your character and the description of it's appearance.
 * In the Edo portion of SaGa 2 on the Game Boy, several townspeople have banana cravings.
 * In Chibi Robo, Jenny's stuffed toy bear Sunshine goes absolutely crazy for flower nectar, to the point where it resembles cocaine addiction complete with withdrawals, hyperactivity, and mood swings.
 * Touch Fuzzy, Get Dizzy.
 * Also In Live Action...
 * Nuka Cola in Fallout is addictive for some reason.
 * Considering that in Fallout 3 you can visit the Washington factory and discover a tremendously long list of side effects from early Nuka-Cola formulae testing, including delirium tremens, dysentery, coma and death, it being ONLY addictive is actually pretty tame...

Web Animation

 * In Homestar Runner, Strong Bad can be seen getting trashed enough to think that Bubs' Concession Stand can take him to the moon... thanks to soy sauce.
 * There are also drinks that are quite obviously "adult beverages," but are always referred to as Cold Ones. Or perhaps Cool Ones on a mild spring day. This makes Coach Z's addiction to Listerine all the more baffling/humorous. Well, there is alcohol in mouth wash, of course.
 * There's also the Strong Bad e-mail "caffeine," where Strong Sad starts buzzing on the titular chemical. The kicker? The coffee he drinks is decaf. Of course, this is completely true to life.
 * In the third episode of Space Tree, Ghost Spider gives the Commander non-alcoholic beer, which causes him to go to jail for drunk flying.
 * Waverly Films made Flamin' Hot Cheetos into a G-rated drug, but it's not a G-rated short.
 * Nutty from Happy Tree Friends is addicted to sugar and behaves as if it were stronger than cocaine.
 * Larxene from Ansem Retort takes it Up to Eleven by getting kicked out of rehab for getting addicted to the placebos
 * In Xanauzumaki's The Legend of Zelda Ocarina of Time abridged series, magic beans are morphed into this:

Webcomics
"Gwynn: Why can't my friends abuse hardcore drugs like normal people?"
 * In Sluggy Freelance the MMORPG "Years of Yarncraft" is frequently treated like an addictive narcotic (how much that's Truth in Television is up to you.)

"Rocky: I CAN SEE ETERNITY."
 * For Kiki the hyperactive ferret, a small amount of sugar is roughly equivalent to a large dose of crystal meth.
 * Instant Classic has pop (especially diet pop) as a standard G-Rated Drug, with the worker at the movie theater concession stand acting as a bartender.
 * The characters in Calamities Of Nature experiment with the slurpee bong.
 * Showbiz from Achewood is addicted to, of all things, Rockford Fosgate automobile audio equipment. He does not have a car.
 * In Nip and Tuck, the Show Within a Show Rebel Cry features bans on caffeine and white sugar.
 * Rocky from Lackadaisy Cats has had an... interesting reaction to pancakes as a child.


 * Of course, having made this claim, the author goes on to posit that this may be incorrect, and it's just all the sugar he's getting from drenching them in syrup. Which is still this trope.
 * Subverted in the first strip of Drugsand Kisses, where the characters obtain a stock cube off their local dealer, only to find to their dismay that it has been partially cut with cannabis resin

Web Original

 * In episode 7 of The New Adventures of Captain S, the main character gets drunk after drinking four milk shakes.
 * Rob Paravonian (Better known as the Pachelbel Rant guy) wrote a song called Pushing Band Candy about his band's fundraiser candy bars, to the point where his ability to hustle these sweets made him something close to (and later an actual) Drug Dealer.
 * A three-part episode of Awesome Video Games has Ace and Chet's cousin Lester come over, essentially acting like a drug dealer, and introduces them to "codes" via the Game Genie for their NES. Side effects include smoke coming out of their NES, a really messed up Super Mario Bros, psychedelic hallucinations, and getting high...scores.

Western Animation
"Let's all smoke crack, instead!"
 * Clone High used raisins, which they rolled and smoked, turning some students into flower children and causing others to go on a bizarre "trip".
 * In a subversion, it turns out raisins don't get you high. It was all a scam by a raisin industry spokesperson to get people to buy them, and all the effects were psychosomatic.

"Krusty: "All this does is get me to normal.""
 * Clone High used that trope twice. In the pilot, Abe is forced to buy non-alcoholic beer for a party, but everyone acts drunk anyway.
 * Of course, this happens in real life, if the drinkers don't know it's non-alcoholic. Even with regular beer, drinkers tend to act drunk long before their body actually gets the chance to absorb the alcohol.
 * So does it mean that thinking yourself immune to alcohol LESSEN its effect on you?
 * In Jackie Chan Adventures, Jackie gets bitten by a poisonous snake, leaving him very thirsty and disoriented during a fight against the Terrible Trio... a perfect set-up for a family-friendly Shout-Out to his movie Legend of Drunken Master. They do this again later, with him getting the bends.
 * An episode of Family Guy had Stewie become addicted to crack pancakes.
 * Another episode has a one-shot gag featuring the Cookie Monster from Sesame Street heating cookie dough like it was heroin.
 * Yet another episode had Chester The Cheetah snorting up ground up Cheetos like cocaine while listening to Rush and proclaiming "there is no fucking drummer better than Neil Peart!" before smashing a glass table with his fist.
 * In the Spongebob SquarePants movie, ice cream was used to make Spongebob and Patrick drunk, complete with 5 o'clock shadow.
 * Something similar happens to Guano in an episode of Kappa Mikey.
 * When Mac from Fosters Home for Imaginary Friends goes into a sugar rush, he acts hyper, selfish and irresponsible, as well as willing to do anything for more. The aftermath is treated like a hangover.
 * People with blood sugar issues can and will experience painful crashes after a fairly intense suger high.
 * It's actually the sugar in alcohol that causes the hangover, so yeah.
 * It's actually the dehydration caused by alcohol that causes the hangover, but too much sugar in the drinks can give you a headache.
 * Rocko's Modern Life did the whole getting-drunk-on-ice-cream thing as well, at Filburt's bachelor party. Heffer even attempts to fly a plane while intoxicated.
 * Done also with Filburt's first taste of candy in the Halloween episode.
 * Rocko's nail-biting was treated like alcoholism, due to the disapproval and embarrassment of his friends and the difficulty he had quitting, which eventually required a 12-step program (in this case, involving a group of cartoonish critters who called themselves "The Twelve Steps").
 * One segment of The Simpsons episode "Love, Springfieldian Style" parodies the Sid Vicious biopic Sid And Nancy, with Nelson as Sid Vicious and Lisa as Nancy Spungen. Since both characters are kids, they use chocolate instead of heroin (they freebase it over spoons, snort it like cocaine, and immediately flush it down the toilet when the police show up). The episode even has a deliberately Anvilicious "Only losers put chocolate in their bodies!" speech.
 * The Simpsons does the not-really-a-drug thing repeatedly: for example, Bart and Milhouse's syrup-only Squishee, or Lisa drinking the "water" on the Little Land of Duff ride.
 * Krusty smokes ground-up moon rocks out of a crackpipe.

"Main Evil Guy: Gentlemen, we are about to make a lot of bread.
 * In Sweet And Sour Marge, Springfield's addiction to sugar is revealed. Disco Stu even refers to it as "the white stuff".
 * Bart and Lisa go on a trip after eating highly potent English chocolate while in London...
 * The trippy episode where Homer eats "The Merciless Hot Peppers of Quetzalshacatenango, grown deep in the jungle primeval by the inmates of a Guatemalan insane asylum", a.k.a. Guatemalan Insanity Peppers ("El Viaje Misterioso de Nuestro Jomer").
 * Getting drunk happens a fair bit in the Simpsons, such as when the family goes to a milkshake carnival and Homer drinks so many he ends up drunk.
 * Bart tricks Rod and Todd Flanders into trying Pixie Stix by telling them they're sugar-free. He then cackles as they instantly get hooked.
 * In "Marge vs. Singles, Seniors, Childless Couples and Teens, and Gays", babies pass around pacifiers like bongs.
 * In the Beavis and Butthead episode "Buy Beer", the boys think they've gotten drunk on non-alcoholic "near beer". They even completely fail a sobriety test, leading the cop to conclude that "You guys aren't drunk... you're just really stupid."
 * In the South Park, episode "Major Boobage", where the concentrated urine that male cats spray in the presence of other male cats gets people high. This causes hallucinations of a fantasy world based on Heavy Metal, where almost everything looks like breasts.
 * In "Guitar Queer-O", Stan goes from playing Guitar Hero at superstar quality to playing Heroin Hero, a game which consists of injecting heroin and chasing a dragon (which cannot be caught). He thinks it's awesome, but rapidly becomes addicted, ending up looking like a pathetic junkie waste, while his skill at Guitar Hero goes down the drain from lack of sleep and practice, and his attitude deterioates. It rapidly ruins his 'career' as a Guitar Hero player and results in him fouling up an important game in public, then throwing up and passing out on the 'stage'.
 * A recent episode lampshades this by treating KFC as an addictive substance, complete with withdrawal, rehab clinics, dealers, cartels, and an eventual chicken war. Hilariously, the episode started with the local KFC being replaced by a medical marijuana dispensary, and the massive influx of crime was blamed on marijuana prohibition being too lenient.
 * In Transformers Animated, oil is often treated as beer. The Constructicons try to get some of decent quality anytime they're not building anything, and Megatron even has his own "private blend" that he drank out of an oil barrel squeezed into the shape of a chalice. However, no one actually gets "drunk".
 * In a slightly more subtle drug analogy, the episode "Fistful of Energon" has the upgrade-craving bounty hunter Lockdown encouraging Prowl to try a few of his upgrades in order to catch Starscream. Prowl finds himself becoming dependent on them and despite his controlled, stoic nature he finds it hard to give them up again. Ratchet even comments that he's seen upgrade addiction before in other younger mechs.
 * However considering Lockdown pries his upgrades off of online bots, that might be more G-Rated cannibalism; and for Prowl and Bumblebee it's more about Pride and irresponsibility.
 * In the original series, episode "Microbots", the Deceptions "over-energized" on Energon and acted drunk.
 * One episode of Courage the Cowardly Dog had people brainwashed into flan addictions. It led to people rioting and raiding the store to get it and Eustace and Muriel stealing a flan truck.
 * An episode of Dexters Laboratory had a "flour" smuggling ring. They even used tacky puns:

Jamaican Guy: I can't wait to be rolling in that dough!"


 * In The Marvelous Misadventures of Flapjack, Captain K'nuckles is a borderline alcohol-esque addict to candy and maple syrup; he even keeps a pint of syrup in his coat pocket, a la whiskey. In the Flapjack universe, candy (or anything sweet) is treated as being somewhere between drugs/alcohol and treasure.
 * One episode of The Snorks featured Bigweed replacing the Snorks' "reefberry" crop with berries that made them act like they were on pot.
 * Codename Kids Next Door treats root beer as regular beer, complete with age restrictions, prohibition-era-style speakeasies that serve it, and kids drinking it at keg parties.
 * There's also the episode Operation: L.I.C.O.R.I.C.E. where Numbah 5 and Black John Licorice have an all-out drinkin match to the death! Did I mention that the drinks of choice were frothy mugs of PURE SUGAR?! To the death, indeed... of your blood-sugar level, that is!
 * In Operation: S.P.A.N.K.E.N.S.T.I.N.E. Numbah 2 reveals in a voice-over that he used to be addicted to chocolate sauce.
 * Monterey Jack in Chip 'n Dale Rescue Rangers has an ongoing addiction to cheese and immediately goes into a bizarre trance whenever he sees or smells it (it's one of the show's running gags), then goes after it, unaware of humans (or anthropomorphic animals) trying to capture him. It's the center of the plot in "Mind Your Cheese and Q's" (probably the only 1980s-1990s "addiction episode" that wasn't Anvilicious, as ), when he tries to give it up.
 * Dale had a similar reaction to chocolate in one episode, which Monterey Jack finds disgusting.
 * Both Drawn Together and Robot Chicken had episodes that revolved around sugar being treated like a cocaine analogue.
 * And Robot Chicken had the "Styx" Rabbit accidentally call it cocaine before quickly correcting himself, Breaking the Fourth Wall in the process.
 * Riley Daring from The Replacements has a full-blown sugar addiction that causes her to go hyper and hallucinate (if her babbling abut being surrounded by dinosaurs is anything to go by).
 * Two Words: Scooby Snacks. That is all.
 * Gumby had a serious milkshake problem.
 * An episode of The Powerpuff Girls has the girls getting a single piece of candy as a reward for saving the day. They instantly get addicted, and make a shady deal with Mojo Jojo to get more. When Mojo steals the candy himself, they beat him to an inch of his life over it.
 * Home Movies has Jason get drunk off candy and trying to seduce Melissa with a kiss.
 * Mrs Flatbottom's lemonade in the Squirrel Boy episode "Flatbottom's Up". The effects of drinking it are displayed as an LSD-style trip.
 * Chocolate Boy on Hey Arnold gets his name from his massive addiction to chocolate, which he often acts like someone who is addicted to crack.
 * The Frosty Freeze Freeze slushie is featured as a major plot point in Fanboy and Chum Chum too many times to let it slip. For an incredibly exaggerated example, see the episode "Berry Sick" - or, for that matter, this sequence.
 * In the Sam and Max Freelance Police cartoon, there were two separate references to a character spending a portion of their life in a hallucinatory daze after eating a bad cheese sandwich.
 * In one Teen Titans episode, Cyborg's dependency on a new Processor was treated like a drug addiction.
 * In the "Over a Barrel" episode of My Little Pony Friendship Is Magic there's a saloon called "The Salt Lick" that apparently serves... salt licks, judging from the bartender's comment when he tossed an apparent drunk out.
 * Then again, in part one of the pilot, Twilight Sparkle pours what looks like an alcoholic beverage into a glass, especially judging by her expression.
 * Subverted by The Looney Tunes Show. When Bugs Bunny starts drinking the soft-drink Spargle, he becomes incredibly manic and goes crazy trying to get more when his stash runs out. But it turns out Spargle's not just a soft-drink; at the end of the episode, the makers of Spargle get arrested for secretly putting "dangerous, highly addictive chemicals" in their product.

Real Life

 * The legend of bananadine. Popularized by the Anarchist Cookbook, this drug was allegedly extracted from banana peels. Unfortunately for people looking to get an easy, legal high, researchers at NYU found that banana peels had no intoxicating chemicals. (They have, however, been known to cause severe headaches when smoked.) This hasn't stopped the urban legend from persisting to this day.
 * Refined sugar, when first introduced into a culture, often produces addictions. One could argue it doesn't really stop...
 * Another form of household "white stuff," plain old salt, can get so firmly entrenched in a culture's palette that people end up consuming much more than is healthy just because they're used to it. It can take months to reduce one's desire for sugar and salt in food, and just get used to what food tastes like without heaps of one or the other. It doesn't help that most prepared food comes loaded with both already.
 * When asked in an interview what his first drug experience was, Eric Clapton said sugar, noting that he used to spread it on bread as a child.
 * The Beatles' "Savoy Truffle" was George Harrison's Take That to Clapton's sugar jones ("Good News" is a UK brand of chocolates). The increasingly-potent Nightmare Fuel sounds realistically enough like a bad trip to the dentist: but it's difficult not to wonder whether some other sort of white powder was being referenced, covertly.
 * Nutmeg is a dissociative hallucinogen, like DXM (which is found in some cough syrup) or datura; it tends to produce solid, realistic, and unpleasant hallucinations indistinguishable from reality. Unlike other drugs, there are very few habitual users - almost nobody who tries nutmeg once ever wants to do it again, even if they enjoy the more "mellow" kinds of hallucinogens, plus, you have to eat several heaping spoonfuls of the stuff to make it work, and even then it can cause difficulty urinating, nausea, cottonmouth, and, most of all, eating all that nutmeg at once tastes pretty bad.
 * Severe overhydration can lead to neurological misfires in the brain, inducing symptoms similar to drunkenness, a.k.a. "water intoxication". Yep, you can get wasted on water, but only if you guzzle enough to overload your kidneys and seriously endanger your body's fluid balance.
 * This is called hyponatremia, and it will kill you. Don't try it.
 * In one standup session, comedian Ralphie May recounts his first experience with "Cuban Coffee" - a Cuban espresso shot reputed to be three times as strong as a regular espresso. At the time he was unaware of this, and so demanded his Cuban coffee - first brought to him as a shot - be returned as a full cup. "For the first thirty minutes, I could see into the future!" he declares, followed by, "and then I put the cup down, and crapped my pants." (Laughter.) "Yes, without any warning, I dropped a deuce. Or as they call it, a dos."
 * Turkish coffee can be extremely potent and serves almost as a replacement for alcohol, which is forbidden according to Islamic law. In fact, when coffee was first introduced into the Ottoman Empire (or it might have been the Seljuks), some Islamic scholars did in fact declare it an intoxicant, and so haram. The government attempted to ban it, which worked even less well than our own equivalents, despite the executions. Another Islamic scholar finally declared that coffee should be allowed because, while alcohol made you lose your focus, coffee increased it, so you would have more energy for your prayers and good deeds. (Which begs the question of whether coffee would be legal for those who weren't intending to do any good deeds...)
 * Gunsmoke to some people. Real gun nuts crave the smell of burnt powder and may let out an exorbitant whoop after firing off their first burst in a long while.
 * Somewhat related (in that burning things are involved,) the distinctive smell of burnt two-stroke oil is one of the main reasons some people are so fond of the two-stroke engine.
 * Sex. Well, for some people.
 * Also love (and, for the more cynical, infatuation). Increased heart rate, lessened coherence and judgemental ability, and dangerous withdrawals? I Can't Believe It's Not Heroin!!
 * World of Warcraft. There's a reason why they call it "Warcrack". By the same token, a lot of things on the Crack is Cheaper page.
 * Diablo II as well. Just google "Diablo II ruined my life". 54,100 results.
 * In Korea, it's Starcraft.
 * Blizzard is an evil, evil company GOD.
 * EverCrack
 * Sid Meiers Alpha Centauri or, as appropriately-initialed SMAC.
 * Bejeweled
 * Minecraft
 * TV Tropes Wiki, see Tropes Will Ruin Your Life and TV Tropes Ruined Your Life for examples.
 * For that matter, any ordinary household drug can be used to get high. Just read about the stories of teens and young adults who have abused all kinds of over the counter medications, from aspirin to cough syrup. It gets even worse when you think about all the medications a doctor can prescribe which are perfectly legal and anyone can get their hands on and abuse without the proper supervision, such as painkillers and antidepressants, which can produce a high very similar to that of those found in street drugs if consumed in large quantities.
 * Some people can actually get high due to a very small amount of prescribed painkillers... especially if they rarely take medication for anything before then.
 * The most commonly abused pharmaceuticals (Rx only) are narcotic painkillers (opiates, i.e. Percocet, Vicodin, Oxy Contin, Morphine, etc), benzodiazepines (anxiolytics/sedatives/hypnotics, i.e. Valium, Xanax, Klonopin, etc), and stimulants (ADD/ADHD/narcolepsy/weight-loss, i.e. Adderall (amphetamine salts), Dexedrine (dextro-amphetamine), Desoxyn (dextro-methamphetamine), etc). Each class has its own specific effects, and different drugs in each class can have remarkably different effects from one-another.
 * Also, some people lack certain enzymes in their liver that are required to metabolize certain drugs/medications at a normal rate, and thus the drug will build up in their system to a higher level than normal, and will remain active for much longer. This is similar to the "red flush" that a percentage of Asian-descent experience when consuming even a relatively small amount of alcohol. Tolerance also plays a significant role, in that while say one 5mg oxycodone tablet may produce significant effects in someone who has never taken any opiates before (and ~50-90mg could be potentially fatal), most people who are on opiate medications long-term (chronic pain, cancer, etc) develop tolerance to where they're taking as much as, if not more than, 80mg of oxycodone 4-6 times per day (close to 500mg daily, 100x the dose of an opiate-naive patient). Same goes for many other medications, and it's also prevalent in addiction.
 * Capsaicin, the active ingredient in hot chili peppers, can make you euphoric, if eaten in enough quantity, as it causes the body to release endorphins. The same principle lends a degree of addictivity to strenuous exercise ("runner's high") and even activities that would seem unpleasant, like cutting oneself.
 * In the absence (or shortage) of oxygen, human cells are supposed to resort to lactic acid fermentation. With the right genetic quirk, they may resort to alcohol fermentation instead (a similar, but not identical process) - so if your personal biochemistry is slightly off, exercise will get you drunk. Try explaining that one to the officer who just pulled you over for a DUI.
 * Chocolate is occasionally mistaken for cannabis by sniffer-dogs and other cannabis tests. This is not made any easier by the fact cannabis is often smuggled inside chocolate, to try to take advantage of this confusion.
 * The placebo effect: Researchers have discovered that if you think you're getting drunk, you'll act drunk even if the drink doesn't actually contain any alcohol.
 * Shown hilariously in this classic Beavis and Butthead clip.
 * A diabetic person with insulin shock looks and acts a lot like a person who's drunk.