Shadowrun/Nightmare Fuel


 * Cyberzombies, which are metahumans implanted with so much cybernetics that they effectively die. Their souls are then forcefully tethered to their bodies through magic and technology. Few last longer than a year before cancer and necrosis rots their bodies away, and most of them aren't what you'd call sane. Oh, and all of this is done completely against their wills by corps who want a temporary asset.
 * Chicago, which ended up suffering an outbreak of nasty insect spirits. Much of the city was blown to hell trying to get rid of them, and what remained was quarantined by the UCAS military, leaving everyone still there to fend for themselves. And that was the good ending of this saga.
 * As an In-Joke, the nuke that was used in Chicago was centered at the location of FASA's headquarters.
 * Bunraku parlors: Yakuza agents acquire pretty girls, either by abducting them personally or through the international slave trade, and have black market surgeons install cyberware that allows the Yakuza to replace their personality with a digital chip. As far as the customers are concerned, the girls are perfectly happy to be there. If the girls are lucky, the chip suppresses their mind to the point of unconsciousness; otherwise...
 * And then there's the Horrors...