Only Sane Man/Web Original

"Strong Sad: Look, you can tell me.
 * Joe in the the flash animations Arfenhouse and Arfenhouse 2 fits this trope.
 * The titular character in Charlie the Unicorn. It doesn't help that the other two unicorns, apart from their blissful acceptance (if not outright knowledge) of all the strange things that occur around them, are really only minor exaggerations.
 * Strong Bad, his brother Strong Sad, and Pom Pom on Homestar Runner. Pom Pom is essentially one of the smartest cast members, and often seems to be telling Homestar that everything he's saying is nonsense. Strong Bad, although he causes trouble, is at least smarter than most of his cohorts (and aware that nobody seems to wear pants). As for Strong Sad...

Homestar: I can't!

Strong Sad: Oh come on! What is it?

Homestar: I'm PWEGNANT!!!

Strong Sad: (pause) No... you're Homestar. Runner. The male.

Homestar: Oh, phew! Thought I was a pwegnant woman fow a second, thewe."

"Grif: "The sun never moves around here! Why does no one ever want to talk about that!?""
 * Marzipan also qualifies at times, although this trait is usually overshadowed by her eccentricity and strawman political zeal. Surprisingly, The Poopsmith is the only character who is always depicted as a rational voice of reason (not literally, of course, considering his vow of silence).
 * Church of Red vs. Blue isn't exactly level-headed, but considering the fact that most of the other regular soldiers in Blood Gulch display varying degrees of incompetence or insanity, he's easily the most down-to-earth character present. While this makes him more proactive than much of the cast, it's also the cause of the endlessly irate disposition that tends to overshadow the other aspects of his personality.
 * Grif would qualify in the respect that he's at least as sane as Church, were he not utterly apathetic to the crazy goings-on of Blood Gulch. Witness his logic in the Warthog argument, which were of course completely shot down by Sarge as being insane and made up. How much of his resulting personality is Flanderization or him just realizing that he cannot make a difference is debatable.

"Washington: I'm not crazy, OK? Now if you'll excuse me, I need to go blow up this dead body. (he proceeds to do so. Multiple times. In his defense, he really, really wanted to be sure she was dead.)"
 * Simmons has also shown himself to be fairly rational when he's not being a sycophant. One could make the argument that the position of Sane Man among Team Red depends on whether or not Simmons is sucking up to Sarge.
 * Washington from Recovery One ultimately fits this the best. It actually creates a weird dynamic where Church mocks the others for their stupidity and the Washingtom mocks him.
 * Again, however, it should be pointed out that in a show where every single member of the cast is crazy or an imbecile, "Only Sane Man" is a relative title. Wash is most assuredly not normal, but compared to everyone else, he's at least mostly all there. In any other fandom he'd be considered a nutcase.

"Narrator: How do I know if the KGB is watching me?
 * GBW in AH Dot Com the Series. About half the time this is played straight, while the other half it's subverted as the universe is so chaotic that a rational approach never yields the right answers.
 * Welshman in Englishman started out like this (and usually turned out to be wrong) while later on he seems to give up and accept the insanity of the Englishverse.
 * While the words "sanity" and "The Nostalgia Critic" don't often go together, he was this in That Guy With the Glasses's April Fool's Day prank, where he got completely freaked out by the questions Ask That Guy gets:

The Nostalgia Critic: Are these really the type of questions he gets? I mean, why do you need to know this? If the KGB is watching you, there's something wrong with you! Why is the KGB watching you? I don't know! Answer that!"


 * The Nostalgia Chick was the Only Sensible Woman before Characterization Marched On and had a bad effect on her sanity.
 * Guy of Life in A Game, being the only "real" person in his video game world, is the only one who questions the insane video game logic that everyone else seems to take for granted. It comes and goes, but the best example of it is in Episode 6-2.
 * Lita in Sailor Moon Abridged, sometimes... and 'she' is a Jive Turkey somehow dressing as a Japanese schoolgirl. Of course, compared to Serena, Raye or Mina...
 * In Dragon Ball Abridged, Vegeta is quite possibly the only sane one around at this point, but it may only appear that way in contrast to some of the idiots (Nappa and Goku specifically) he's put up to.
 * Freeza arguably counts as well. Or at least he's Genre Savvy.
 * Nathan from Shiny Objects Videos tends to fill this role.
 * In the first act of A Very Potter Musical, Hermione frantically tries to convince the other characters that the House Tournament is dangerous, but their reaction is pretty well summed up by Harry's line: "Duh, Hermione, I'm the Boy Who Lived, not Died". Later on, in the second act (after Hermione has been proved right), Harry gets a turn: Voldemort has returned, but whenever he tries to talk about it with someone, they change the subject to their love lives..
 * Dr. Tran fits this trope perfectly, especially when the narrator's around.
 * Cyd/Codex in The Guild appears to be the only member of the guild in tune with reality.
 * Tom fills this role in most episodes of We Need Girlfriends
 * Ab3, the Author Avatar in The Binder of Shame.
 * Used in Yu-Gi-Oh the Abridged Series: The Other Abridged Movie. The Only Sane Man here would be Gary Stu, who can't understand why people are so obsessed with card games -
 * Perhaps due to a Near Death Experience in the previous season ("I CAN'T BELIEVE I'M GOING TO DIE IN A SHOW ABOUT (BLEEP)ING CARD GAMES!"), Duke Devlin is starting to become more or less the Only Sane Man in season 3.
 * Dan O'Brien from Agents of Cracked is the only sane main character but is completely unbalanced compared to the periphery characters that are actually normal.
 * Gordon Freeman as depicted in Freemans Mind is not a sane individual by any standard, but everyone around him is so much more insane/stupid/violent that it's really hard not to see him this way. He even says flat out at the beginning of episode 13 "Everyone is crazy but me!".
 * Derek the Bard is surrounded by a crazy Lethal Chef, a truly pathetic vampire, a mad scientist supervillain, and Cthulhu. No wonder he hits the crystal skull vodka so much...
 * Dana. Tom is a Jerkass, Zack is a Cloudcuckoolander, Shannon is a Yandere, Porn Girl is... Porn Girl, and Mr. Administrator is a Bad Boss.
 * Sasha Hunter in Greek Ninja finds herself rolling her eyes all the time at her comrades' antics.
 * The Shark Pool trailer features one guy whose suggestion for stopping the shark from killing people is to not go into the pool it's trapped in. No one else seems to see it this way.
 * Coltaine from Dungeons and Drogans often laments this.
 * Yasaki in Transolar Galactica.