X Meets Y/New Media

Creativity meets the Interweb:

Web Animation

 * Red vs. Blue was described by critics as "Star Wars meets Clerks''."
 * Really, it's more like Halo meets Clerks.
 * Super Mario Bros Z is Super Mario Bros. meets Sonic the Hedgehog with Dragonball Z physics.
 * Awesome Series is Brawl in the Family meets Ren and Stimpy meets FLCL.
 * APPLE.MOV answers the question "What would My Little Pony Friendship Is Magic be like if it was created by Jon Kricfalusi instead of Lauren Faust?"
 * Minus John K's rampaging ego.
 * Collegehumor.com did CSI meets Scooby Doo in this video.
 * An animation called "Heroes" is Clerks the Animated Series meets the Marvel Universe.

Web Comics

 * Abby's Agency: James Bond meets Dilbert.
 * Exterminatus Now: Sonic the Hedgehog meets Warhammer 40,000.
 * Hello Cthulhu: The Cthulhu Mythos meets Hello Kitty. Which is basically the entire point.
 * Darling Destroyer: Lulu Cthulhu: The Cthulhu Mythos meets Magical Girl Mythos.
 * Captain SNES: Captain N: The Game Master meets Chrono Trigger... as a Sprite Comic with a very strange set of fourth walls.
 * Irregular Webcomic: Dungeons & Dragons meets Crocodile Hunter meets Shakespeare meets Indiana Jones meets MythBusters meets GURPS in space meets Star Wars meets Harry Potter meets James Bond meets Terry Pratchett meets H.P. Lovecraft. Literally.
 * There is also an Ancient Rome section, though it doesn't show up that often. Also, the different aspects of the strip sometimes do crossovers. (They're normally separate. It's like ten or twelve comics in one.) Also, every Christmas brings H.P. Lovecraft meets a classic Christmas carol.
 * Order of the Stick post-Cerebus Syndrome: Eight Bit Theater meets Fire Emblem.
 * According to Cortland, Dilbert + gaming = PvP.
 * Last Res0rt: The bastard child of Ratchet and Clank and Gold Digger (and raised by The Running Man, we think).
 * Shadowgirls: Explicitly described on the main page as "H.P. Lovecraft meets the Gilmore Girls."
 * Code Name: Hunter: Danger Mouse meets The Dresden Files.
 * Bear Nuts: Care Bears meets Happy Tree Friends meets The Hair Bear Bunch.
 * Gunnerkrigg Court is best described as Harry Potter meets X Files.
 * With a little Nancy Drew thrown in there.
 * Aoi House: Genshiken meets Love Hina... in America!
 * Guardians: Land of Legends has often been described by the author as Avatar: The Last Airbender meets Chronicles of Narnia.
 * Lucid TV is Perry Bible Fellowship mating with Scrubs. Cheerfully.
 * College Roomies from Hell!!! used to be described by the author as Friends if it was written by H.P. Lovecraft.
 * Freak U is Revenge of the Nerds meets Misfits of Science meets Sabrina And The Groovy Ghoulies.
 * Thomas K. Dye's weekly comic Something Happens is usually described as The Far Side meets Monty Python.
 * Sonichu started out as Sonic the Hedgehog meets Pokémon, as drawn by your kid brother. Since then, it's become "Everyone Else Has Had More Sex Than Me" meets The Punisher, as drawn by your kid brother.
 * Homestuck = EarthBound + Spore + The Sims, according to Word of God.
 * Double K = Tengen Toppa Gurren Lagann + Starsky and Hutch
 * Hanna Is Not a Boy's Name is Dresden Codak meets Angel in a sausage factory.
 * Collar 6 is a Shonen manga meets BDSM.
 * Bittersweet Candy Bowl is Degrassi the Next Generation meets Housepets
 * Sparkling Generation Valkyrie Yuuki is The Mighty Thor meets Sailor Moon meets Ranma ½
 * Superego is Nine Hours, Nine Persons, Nine Doors meets House of Leaves meets the Persona series.
 * Spinnerette is Empowered meets Spider-Man
 * Ron Planet is Space Cowboys meets Invader Zim meets Homestar Runner.
 * Fans: Genshiken meets The Lone Gunmen.
 * Digger: Bone meets Discworld.
 * Precocious: Ozy and Millie meets Cul De Sac.
 * Seventy Seas: One Piece meets Usagi Yojimbo

Web Original

 * Sailor Nothing: Sailor Moon meets Watchmen, or perhaps Neon Genesis Evangelion.
 * Re\Visioned: Tomb Raider - Pre-Teen Raider: Tomb Raider meets Kim Possible
 * There Will Be Brawl: Sin City meets Super Smash Bros.. with a good helping of The Silence of the Lambs thrown in.
 * Laconic: TV Tropes meets Twitter.
 * Whateley Universe: Gender Bending and Author Appeal/Fetish Fuel meet X-Men, with some occasional Cthulhu Mythos.
 * Unskippable: MST3K meets... more MST3K.
 * Wormtooth Nation: A Midsummer Night's Dream meets Dark City IN A SUBTERRAINEAN STEAMPUNK WORLD!
 * Fandom Secrets: Post Secret meets....TV Tropes.
 * Darwin's Soldiers is Die Hard meets X-Men meets Half Life meets Resident Evil meets furries.
 * Candle Cove is The Marvelous Misadventures of Flapjack meets The Twilight Zone.
 * Harry Potter and the Methods of Rationality is Harry Potter meets Ender's Game.
 * The Slender Man Mythos as a whole are Cthulhu Mythos meets The Internet.
 * Marble Hornets is The Blair Witch Project meets The Ring, with a dash of The Chzo Mythos on top.
 * Seeking Truth is Dirty Harry meets A Study in Emerald.
 * The Global Guardians PBEM Universe: Justice League of America meets The Young and The Restless.
 * Checkpoint (formerly Escapist News Network) is X-Play meets The Daily Show.
 * Yu-Gi-Oh!: The Abridged Series is Mystery Science Theater 3000 and Space Ghost Coast to Coast meets Yu-Gi-Oh!.
 * Chaos Fighters II-Cyberion Strike is Chaos Fighters meets Mega Man Battle Network and Mega Man Star Force. Chaos Fighters II-Chemical Siege and Chaos Fighters: Chemical Warriors-KIMIA are Chaos Fighters meets Element Hunters.
 * The Chimera Bazaar is Cthulhu Mythos & Ancient Mythologies meet xxxHolic with a hint of Fruits Basket
 * The Salvation War is 'World War Z' meets The Book of Revelation
 * Apocalypse Johto is Poke Wars running under Nuzlocke Comics rules.
 * CollegeHumor's Troopers is Bob & Steve meets Star Wars.
 * Incognito Cinema Warriors XP is Mystery Science Theater 3000 meets Resident Evil
 * Journey Through the Multiverse is Kingdom Hearts as written by Gen Urobuchi and Yoshiyuki Tomino.
 * At the Modules of Madness: pseudorandom text generated from documentation of Puppet (software delivery and infrastructure system) and the assorted works of H. P. Lovecraft. (“Puppet always uses the same default ACLs as puppet master, which allow access to the marvellous golden spires of Thran.”)

Web Comics

 * Black Mage Evilwizardington: Lina Inverse (especially her Revolution characterisation) meets Eric Cartman, with a dash of Bender's personality.
 * According to the man himself, 8-Bit Theater's Fighter + swordchucks = "...like Bruce Lee meets Musashi, only better!"
 * Xykon: The Joker meets Lord Voldemort.
 * Vriska Serket: Sho Minamimoto tempered by Morrigan.
 * Rayne: Ethan meets Charlie Harper.
 * Vexxarr: Zim meets Rincewind

Web Original

 * HABIT: totheark meets Killer BOB.
 * Doctor Sloth is The Grinch meets Doctor Neo Cortex.
 * Rick Wolf is Mike Nelson meets Chris Redfield.