One of the Seven Signs of the Apocalypse

Something of a Stock Phrase, this is a common humorous hyperbole used to emphasize how unlikely a given event or action is in the current context. Alternately, it can be used to suggest that something is so awful that must be a sign of the impending end of the world, usually with a knowing wink at the exaggeration.

In use it takes either a declarative form ("X is One of the Seven Signs of the Apocalypse.") or an interrogative ("Isn't X One of the Seven Signs of the Apocalypse?").

The Trope Namer (but not an example), of course, is The Bible, and references the Seven seals which are opened in Chapters 5-8 of the Book of Revelation; as each is opened a judgment is released or an apocalyptic event occurs, which are the actual signs.

Note that this trope is not about the serious use or identification of current or historical events as literal signs of an (or the) Apocalypse, or speculation on the same. It is only about amusing hyperbole.

Literature
""Well, hell," Tod hooted. "Allen disagrees with you, Maya. Isn't that one of the seven signs of the apocalypse?""
 * In Zombie Zero: The First Zombie by J.K. Norry, there is the following passage:

"While most people look toward a nuclear Iran or melting ice caps to get a heads-up on the end of the world, I train my eye on the programming of the Hallmark Channel. The more modern the time frame and the more cynical the casting, the closer we are to the end of the world. For example, if you see a Hallmark movie entitled The Search for Mrs. Santa starring Liza Minnelli and Simon Cowell, consider it one of the seven signs of the Apocalypse."
 * The Dangerous Animals Club by Stephan Tobolowsky has this comment at the beginning of its 22nd chapter:

""Did Mama just hand me a cup of human blood and then make a joke about a horror movie?" I asked Jenny, who nodded, all astonishment. "Doesn't the Bible list that as one of the seven signs of the Apocalypse?" "Well, not in the King James version," Jenny said."
 * In Nice Girls Don't Bite Their Neighbors by Molly Harper:

Live-Action Television
"Judy: [to Christina] Hey, you're falling in love, it's not one of the seven signs of the apocalypse... Is it?"
 * In episode 10 of the 2005 FOX series Point Pleasant, there was this line of dialogue:

Web Original
"Rumor has it that Jersey Shore's Snooki is preggers. Since this is clearly one of the seven signs of the Apocalypse, we’ll keep this short. How long before we see this magazine cover?"
 * A 2007 essay at Humorpress.com explicitly proclaims The Bachelor one of the seven signs.
 * Mad Magazine's website has a page about a 2012 rumor that Snooki from Jersey Shore was pregnant. It introduces a parody of a Vanity Fair cover with

"If the show had started any later, [Vogue editor Anna Wintour] might have started posing with people and delivering phone-cam shout-outs to their mothers. We believe that’s one of the seven signs of the apocalypse, so keep an eye out for it. The world can’t end before Fashion Week does."
 * A 2010 article about a fashion show at thecut.com, a spinoff of NYMag.com, ends with

"Taco Bell Is Making a Taco Shell Out of Fried Chicken Isn't this one of the seven signs of the apocalypse?"
 * And Maxim's website actually uses the phrase in the headline for an article:

Web Video

 * In episode 3 of Bad Obsession Motorsport's Project Binky, narrator Richard says, "I'm sure that Nik not using a grinder when the opportunity presents itself is one of the seven signs of the Apocalypse."