Fallout 3/Fridge

Fridge Brilliance

 * The names of the weapons in Mothership Zeta are incredibly generic and dull, "alien atomizer", "alien disintegrator", "drone cannon", etc. Then you realize these aren't their actual names, they're just the names your character has given them in-universe to tell them apart, they probably have proper names but there's no way you could ask the aliens to tell you.
 * East Coast super mutants getting Stronger with Age neatly justifies Fawkes being such a Game Breaker with Broken Steel: He's an original super mutant, nearly 200 years old, making him potentially much older than the muties you and he chew through. And he still has all his faculties.

Fridge Logic

 * Pretty much everything to do with Little Lamplight. The town has been around since the bombs hit, but where do the citizens come from since it is only populated by children and the adults are sent away? It also lies right next to the Vault the super mutants come from, and in fact a door in the town connects right to the Vault, so how is it they haven't been wiped out? And when you grow older you're sent to Big Town—it's halfway across the wasteland, why is it so far away and how did anyone survive the journey there when from what you see they're sent off with nothing but the clothes on their backs?
 * Assuming contemporary real-life standards, puberty generally occurs somewhere between 9 to 14 years of age. The Little Lamplight exile age is 16, so there's enough time for reproduction.