File:Gyllenhaalsromcom 7746.jpg

This looks to be a heavily-edited parody of the Entertainment Weekly #1130 cover, dated 26 Nov 2010. The original cover had caption "Jake and Anne: On sex scenes, chemistry and their surprising new movie LOVE & OTHER DRUGS.

It is unclear *who* created the derivative work. The original cover photo depicted Jake Gyllenhaal, Anne Hathaway from this film.