Shut UP, Hannibal/Live-Action TV

Examples of a reaction in  include:

"Simmons: Bridge to engine room, come in. Conrad: What is it? Simmons: Are we gonna get into hyperdrive any time soon, here? Conrad: I'm working on it. The design is incredibly crude. It amazes me that a race as backward as yours could even think of attempting interstellar travel. Simmons: Spare me the super-villain riff. We're on the clock here."
 * In the Stargate SG-1 episode "Prometheus", there is a wonderful exchange between Simmons and Conrad :

"Heru'ur: You DARE DEFY ME? O'Neill: I was thinkin' about it. (throws knife into Heru'ur's ribbon device)"
 * There's also this exchange between Heru'ur and O'Neill:

"The First: I’m not a demon, little girl. I am something you cannot even conceive. The First Evil. Beyond sin, beyond death. I am the thing the darkness fears. You’ll never see me but I am everywhere. Every being, every thought, every drop of hate - Buffy: All right, I get it. You're evil. Do we have to chat about it all day?"
 * In the Buffy the Vampire Slayer episode "Lie to Me", Buffy's old friend is going to hand her and a bunch of innocent people over to Spike in exchange for being made a vampire. He gives Buffy a long speech about how he's dying and in pain. Buffy listens, and tells him she feels sorry for him... but if he goes through with it, she'll kill him herself. Commence ass-kicking.
 * This is something of a speciality of Buffy's. Buffy's sass has won out over even the most carefully constructed Break Them by Talking.
 * "You have fruit punch mouth."
 * Season Three, "Amends":

""Looks good, doesn't it? They're trapped in here. Terrified, meat for the beast, and there's nothing they can do but wait. That's all they've been doing for days, waiting to be picked off, having nightmares about monsters that can't be killed. But I don't believe in that. I always find a way. I'm the thing that monsters have nightmares about. And right now, you and me are gonna show 'em why."
 * One of her boyfriends picks up on it too. Recurring human villain Ethan Rayne walks away while delivering a lecture on why Buffy can't kill him. He walks straight into Riley, who arrests him.
 * Subverted in the scene where Willow cuts Warren's excuses with "bored now" and kills him. The subversion is that by doing so, she becomes a bigger villain than he.

"Crow: Keep the money. Use it to buy a funeral. It doesn't matter where you go or how far you fly. I will hunt you down, and the last thing you see will be my blade. Mal: Darn. (kicks Crow into Serenity's engine)"
 * There are probably a lot of examples in Firefly, but this one from "The Train Job" stands out:

"Lund: The In'e'pen'ents were a bunch of inbred, cowardly piss-pots. Should've been killed off of every world spinnin'. Mal: [turns] Say that to my face. Lund: I said you're a coward and a piss-pot. Now what are you gonna do about it? Mal: [smiles] Nothing. I just wanted you to face me so she could get behind you. [Lund turns, and Zoe knocks him out with the butt of her rifle]"
 * Also in "Train Job"

"Zoe: Him. Oh, I'm sorry, you were going to ask me to choose, right? Do you want to finish?"
 * Similarly, in "War Stories", when Zoe deprives Niska of his speech when she chooses.

"Zoe, Wash, and Jayne come across Mal's struggle with his tormentor. Jayne raises his pistol, but Zoe stops him. Zoe: Jayne. This somethin' the Captain has to do for himself. Mal: No! No, it's not! Zoe: [surprised] Oh. They open fire, killing the torturer."
 * Another in War Stories, where it is subverted; Mal has to invoke a Shut Up Hannibal from his crew:

"Davros: I will transform Skaro's sun into a source of unimaginable power and with that power at my disposal the Daleks shall sweep away Gallifrey and its impotent quorum of Time Lords! The Daleks shall become lords of time! We shall become all- The Doctor: Powerful! Crush the lesser races! Conquer the galaxy! Unimaginable power! Unlimited rice pudding! Et cetera, et cetera!"
 * In the pilot, where Dobson is holding a gun to River's head, the Fed starts in on what he's going to do if anyone moves. Mal, who is just heading aboard the ship, ends the speech by shooting him in the head. Without even breaking stride.
 * In Scrubs, Cox's therapist gave him a Break Them by Talking after Cox constantly made fun of him instead of listening. It went about something like why Cox is how he is and how pathetic and sad he really is behind his Jerkass Facade. Dr. Cox replied with crying like a baby in an overly sarcastic manner, saying "Give me a break" and leaving.
 * Later Laverne gives Cox one, so it goes both ways.
 * Doctor Who: in "Remembrance of the Daleks" the Doctor got what may be the greatest example of this yet.

"Davros: It is time we talked, Doctor, after so very long... The Doctor: No no no no no, we're not doing the nostalgia tour! I want to know what's happening right here, right now."
 * Another one between the Doctor and Davros is in "Journey's End", the last episode of season four of the new series:

"The Doctor: After all this time, after everything we saw, everything we lost, I have only one thing to say to you... BYE!"
 * And earlier, after Davros tries another lecture:

"The Master: I am the Master! Peri: So what? I'm Perpugilliam Brown and I can shout just as loud as you can."
 * "Planet of Fire" features this wonderful exchange when Peri first encounters the Master:

"The Editor: Well, now, there's an interesting point. Is a slave a slave, if he doesn't know he's enslaved? The Doctor: Yes. The Editor: Oh, I was hoping for a philosophical debate. Is that all I'm going to get, "yes"? The Doctor: Yes."
 * Especially good as he was trying to hypnotize her at the time. It is also the only time The Master ever fails to hypnotize a human being straight out, and no reason for this is ever given. Apart from the fact that she can shout just as loud as he can.
 * Another example is in the episode, "The Long Game", when the Ninth Doctor is captured by the Editor of an evil news channel, secretly controlling the thoughts of every single human.

"The Doctor: If you want orders, follow this one. Kill yourself. Dalek: The Daleks must survive!! The Doctor: (literally foaming at the mouth) The Daleks have failed! Now why don't you finish the job, and make the Daleks extinct?! Rid the universe of your filth! WHY DON'T YOU JUST DIE?! Dalek: (Beat) You would make a good Dalek."
 * There's a very good one in 'Dalek':

"Son of Mine: War is coming. In foreign fields, war of the whole wide world, with all your boys falling down in the mud. Do you think they will thank the man who taught them it was glorious? Headmaster: Don't you forget, boy, I've been a soldier; I was in South Africa. I used my dead mates for sandbags. I fought with the butt of my rifle when the bullets ran out and I would go back there tomorrow! For King and Country!"
 * A non-verbal villain-on-villain one occurs in "End of Time Part 2".
 * In episode 6 of The Reign of Terror, Robespierre is arrested. He is about to make a speech when he is shot in the jaw.
 * Let's not forget the first confrontation with the Dalek Emperor in The Parting of the Ways. The Daleks begin shouting at the Doctor after he 'blasphemes' to which he turns round, shouts 'SHUT UP!' and says 'Sorry about that, where were me?'
 * The Headmaster delivers a good one to Son of Mine in Family of Blood. It ends the discussion and Son of Mine has to pull out his weapon.

"Cannibal: (to Booth) You don't understand; it's a spiritual right to share the life force... Booth: Look, you're nuts, okay? We get it. We don't need to hear the rambling psycho speech on why you did it. Cannibal: (to Bones) You're an anthropologist. You know that ancient civilizations would sacrifice some in order to preserve the strength... (Bones knocks him out with a bedpan) Booth: What'd you do that for? Bones: Nobody wants to hear that rambling psycho speech."
 * Rory Williams gets A Shut Up Hitler moment. Then puts him in a cupboard.
 * House: Cole finally earns House's respect when he counters House's mind games by punching him in the jaw.
 * On Prison Break, after Mahone's Heel Face Turn his son is killed out of retribution. Mahone captures the man who did it, gets insanely brutal in torturing him until he calls Mahone's wife and apologizes, then leads him to a dock tied to a bunch of weights. The killer starts a speech to Mahone about how they aren't any different, only for Mahone to push him into the water after just a few words.
 * In the Stargate Verse, the heroes are way too Genre Savvy to put up with the hammy villains. O'Neill is probably the exemplar here.
 * A double Shut UP, Hannibal from the "Man in the Bear" episode of Bones involving, appropriately enough, a cannibal:

"Bones: I've noticed that very few people are scary once they've been poked in the eye."
 * Also Bones. In the episode The Man in the Morgue, set in New Orleans, the killer starts going into a harangue about the power of Voodoo. Bones shuts him up by poking him in the eye.

"Sylar: (feigning shock) From cheerleader to stone-cold killer! Who's the monster now? (Claire pauses. She pumps the shotgun, looks at Angela, then suddenly turns and blows the phone away. Sylar stares at his cell phone as it beeps a busy signal at him.) Claire: You are."
 * In The Man on Death Row while Bones and Booth face the revealed killer in prison, he begins a rant about how their actions have ensured the success of his plans and his continued life. When they turn to leave, he tries to stop them so he can continue his monologue... only for Brennan to break his arm on the table.
 * In the third volume finale of Heroes, Sylar takes over the Company building in one long, drawn-out attempt to push its few remaining inhabitants over the edge and prove that they're all as bad as he is. It eventually reaches the point where makes an over-the-phone offer to let them go free if Claire will just be a dear and shoot Angela. Claire, enraged, threatens to kill him if she gets out alive.

"Caine: Because you're evil, you enjoy death, I hope you enjoy your own."
 * An episode of CSI: Miami ended with a serial-killing sniper being arrested and asking if Caine wants to know why he did it. Caine declines, not wanting to know the intent because the man's a sick fuck, and orders the officers to take him away.
 * Even better, he threw the guy's real motives back in his face with a Lecture To Hannibal:

"Nicole: Who helped you concoct that theory, your mother? Goren: In her wildest delusions she never spawned anything like you, Nicole."
 * In a crossover with CSI New York, a psychopath, after going on a killing spree in two states, thanks Mac for "looking after him" when no one else would. Mac tells him to shove it, saying that many people have had worse lives and didn't turn out evil.
 * Law and Order: Criminal Intent: Det. Robert Goren's Arch Nemesis Nicole Wallace taunts Goren about his schizophrenic mother and his neglectful, philandering father on various occasions, only to have Goren turn the tables on her each time. In "Anti-Thesis" and "A Person of Interest", Goren switches the topic to Nicole's sexually abusive father. In "Great Barrier", the following exchange takes place when Goren accuses Nicole of :

"Dale: Hey! Come back here! I'm not finished! Monk: (quietly) Oh yes, you are."
 * Battlestar Galactica: Lee is confronting Phelan, the head of the fleet's Black Market. The black market gets things such as food and medical supplies to people who need them. But Phelan has also pressured people into giving up their children to be child prostitutes as payment. Often for the medicines. Phelan gives Lee a Hannibal Lecture ("It's hard to see the high ground when we're all standing in the mud...") and Lee points a gun at him. Phelan is completely unfazed, convinced that Lee won't shoot as they are not alike... and Lee shoots him in the chest. He then tells Phelan's cronies that the child prostitution and the withholding of medicines stops NOW. If it doesn't, he'll know. And he'll be back.
 * At the end of "Mr. Monk is on the Run", Monk confronts his arch-nemesis Dale the Whale, who is in prison due to Monk's actions. Dale gloats at Monk, telling him that while he (Dale) is in jail, it's Monk who is a prisoner, trapped by is own hang-ups and neurosis. Monk looks at Dale, then simply turns his back and walks away.

"Dr. Daniel: You're ambitious, more than you let anyone see. A girl from nowheresville, desperate to make it big, but you're worried that you'll always be smalltown, smalltime, you haven't got what it takes, and that's why you're so shut down to everything but this job. Van Pelt: Dr. Daniel, no offense, but I've been working with Patrick Jane for nine months now. You wanna get under my skin, you're gonna have to up your game."
 * Smallville: In the episode "Lara", Clark Kent gets exposed to kryptonite and falls on his face. A government agent approaches him with handcuffs and rants about how aliens are all dangers to national security, only for Clark to pop up and deck him.
 * In the episode "Spell", the evil witch Isobel mocks Clark, ranting about how his powers are nothing compared to her reality-bending magic, only for Clark to incinerate her spellbook with a shot of heat vision.
 * Lionel Luthor gets at least one too. In one Saw-like episode, called "Mercy", a crazy employee is forcing Lionel to go through an obstacle course to fight for his life while boasting over a loudspeaker about how Lionel will probably die instead of escaping. At one point, Lionel's captor asks "So have you learned anything yet?", to which Lionel sneers "Yeah. You talk too much. Shut up," right before successfully completing the task at hand and moving to the next stage of the obstacle course.
 * Subverted in the episode "Supergirl". Gordon Godfrey is giving a villainous speech about how humans are frail and pathetic and that heroes cannot accomplish anything when Clark tells him to cut the crap and tell him where Lois Lane is being held prisoner. Godfrey ignores him and continues where he left off, causing Clark to lose his temper.
 * In the final episode of Angel both hero and villain get a turn at this. First, in the midst of their climactic fight, Angel lectures Hamilton on how people who don't care about other people will never understand people like Angel, who do. Hamilton dismisses this in five brilliant words: . Then, as the fight continues, and Hamilton gains the upper hand over the vampire, he begins to boast about his own awesomeness, ending with: "The power of the Senior Partners runs through my blood!" Angel picks himself up, and smiles almost pitying at him before saying And then, with his Game Face still on, he gets another perfect one-liner after draining him. "Wow, you really are full of it." (licks his finger). There is one final one at the end of their fight, when Hamilton boasts: "We are legion. We are forever." Angel breaks Hamilton's grip, and proceeds to pound him saying "Then I guess forever, just got a hell of a lot shorter".
 * In the final episode of The Wire, when.
 * Done very bluntly in "Private Plane" from Blackadder Goes Forth - on being caught by Baron von Richthoven, Captain Flashheart appears to listen to the Baron's gloating speech for about a minute before suddenly shooting him dead mid-sentence with the observation "What a poof!"
 * Possibly to the point of being a subversion, since the Baron's speech is more along the lines of "Wow, I finally get to meet the great Lord Flashheart! As men of honour, we'll surely have so much in common and will have a glorious and dignified duel with each other!" than a Break Them by Talking, thus making the Lord look like a bit of a dishonourable prick.
 * Dean Winchester isn't about to fall for "that sympathy-for-the-devil crap," not even when the actual Devil tries it on him. But then, Dean is a simple man and figures that if someone  then no matter how much he tries to argue that Humans Are the Real Monsters and that God was unfair to him, he's still what is commonly known as "the bad guy."
 * Jessie, the  tells the Demon who is possessing his mom to sit down and shut up, who was in the process of telling him that everyone he ever knew lied to him. This is after Sam tried telling the truth. After Sam tells him the truth, Jessie banishes the demon from his mother. Doubles as a Crowning Moment of Awesome for the little guy too.
 * The Mentalist: Watching Patrick Jane in action has made his colleagues less awed by others doing a Sherlock Scan.

"Delenn: "You are a creature who has received pain and given pain, and taken too much joy in its application. You have aspired to dreams and been disappointed because you are not strong enough, or worthy enough, or righteous enough, so you lash out at anyone who believes they can make a difference, because it reminds you of your own failure. You have to prove they're just as bad, just as flawed as you are. Am I close, Mr. Sebastian?" Inquisitor [hits his Magitech cane on the floor, electrocuting Delenn]: Bang!"
 * Funny, because Daniel's speech closely mirrors the original Hannibal Lecture.
 * Criminal Minds: At the end of "100",  Which is a preamble to the show's ultimate What You Are in the Dark moment:
 * A rare (sort of) villain-to-hero example occures in Babylon 5, episode "Comes the inquisitor". After a lengthly questioning/torture/ by the titular inquisitor his inerviewee Delenn decides to feed him some of his own medicine and deconstruct his cruel and nihilistic performance. It doesn't come out too well (or perhaps it does come out too well, it's just that he is not inclined to allow it to pass).

"Picard: You say you are true evil? Shall I tell you what true evil is? It is to submit to you. It is when we surrender our freedom, our dignity, instead of defying you. Armus: I will kill you and those in there. Picard: But you will still be in this place. Forever, alone, immortal. (Armus begins growling) That's your real fear, never to die. Never again to be united with those who left you here. (Armus begins screaming) I'm not taking you anywhere."
 * In the Star Trek: The Next Generation episode "Skin of Evil", Picard gives an epic speech to Armus, the malicious being who murdered Tasha Yar and tortured Riker and gloated about it to a trapped Counselor Troi:

"Borg: "We are the Borg. Existence as you know it is over. We will add your biological and technological distinctiveness to our own. Resistance is fu--" [Species 8472 promptly obliterates both cubes.]"
 * Star Trek: Voyager had an Evil vs. Evil variant with two Borg cubes hailing Species 8472 in one of the shortest (and possibly funniest) teaser openings ever.

"Maxwell: You know, Frank, I'm getting bloody tired of kissing up to you... C.C.: (interrupting) I'm not. Let me do it... Maxwell: Miss Fine was right from the beginning. I should never have forced my little girl to play with your son. Quite clearly, he deserved everything he got. And I don't care for what you think of my play, and frankly, I don't care much for you, either. Now, let me show you the door. (gesturing behind him without turning) It's over there."
 * A recent storyline on Neighbours had Susan stalked by someone who turned out to be her University lecturer, who blamed her for failing him when he was a student teacher at Erinsborough High. Despite the hell he had put her in recent weeks, Susan refused to take any crap from him, telling him that he had no one to blame but himself for repeated failures to learn from his mistakes.
 * Tsukasa from Kamen Rider Decade is a master of this, to the point it happens at least once per story arc, normally leading to his Catch Phrase "I'm just a passing through Kamen Rider, remember that!"
 * NCIS delivered a very effective one to Abby's Stalker with a Crush without saying a word. As he's being interrogated at the end, the stalker keeps addressing the two-way mirror, taunting Abby with claims that they're drawn to each other -- "Right now, you can't take your eyes off me, can you?" Gibbs responds to this by leaving the interrogation room, reaching into the other, and flipping on the lights, revealing that nobody's there watching. Loser stalker doesn't take it well.
 * In The Nanny episode "Sunday in the Park with Fran", Maxwell Sheffield and C.C. Babcock, his business partner, try to curry favor with theatre critic Frank Bradley by having Maxwell's daughter Gracie go on a play-date with the critic's son, Frank Jr., even though Gracie insists she doesn't like him and Fran supports her. During the play-date, Fran hits Frank Jr. with a baguette because he was bullying Gracie, so Maxwell arranges for a meeting with Frank Sr. for Fran to apologize. But when he becomes incredibly hostile towards Fran, Maxwell decides enough is enough:

"Genetically Engineered Thug: 452... Max: Just bring it!"
 * Glee: Will gets a moment after Sue bursts into the Glee club's room with a trophy in her hand, loudly talking about how she'll turn it into a trophy room. After she gives a little rant about how they have no chance at Regionals, Will walks up to her, grabs the trophy out of her hands, then throws it against the room's wall, smashing it to pieces. Shut UP, Hannibal! at its finest.
 * On one episode of Blue Bloods, a serial rapist is holding Erin hostage at gunpoint and tells Frank to Put Down His Gun and Step Away. Frank shoots him in the head in mid-sentence.
 * Max ("452") cuts short an opponent's pre-fight monologue in the series finale of Dark Angel.

"Raylan: Why wait?"
 * On Justified the increasingly unstable mobster Quarles approaches Raylan in a bar and tells him that he is going to kill him sometime in the future when Raylan least expects him. Raylan's response is to pull out his gun and fire a shot into the ceiling.