- Hey, It's That Guy!:
- Lane Myer upgraded from speeding in a station wagon to stunt driving in a limo. The again, this isn't the first time John Cusack was a limo driver.
- Speaking of which, the last time John Cusack and Amanda Peet were last seen together, he was said limo driver and she was a prostitute.
- Woody Harrelson is no stranger when it comes to dealing with end-of-the-world apocalypses. Unlike this one, he actually survives the last one.
- Dr.Phlox as a scientist.
- Chiwetel Ejiofor, probably best known here as The Operative.
- Thandie Newton
- George Segal as Tony, whose been in so many things, just check out his IMDB page.
- Harry, character and voice actor Blu Mankuma
- Det. Sgt. Murtaugh as the President.
- Mr. Lau and the Russian Prima Ballerina from The Dark Knight. The former is down on his luck and makes his living as a construction worker, the latter became the oligarch's girlfriend.
- For those fans of fake psychics and real detectives
and delicious flavor, we didn't wonder why Noah (alias Shawn Spencer, age 10ish) didn't figure it all out before.
- The Navy Thunder Ranger is one of the chefs on the boat Harry and Tony are on.
- Hollis Mason as the Captain of Ark 04.
- Dean Marshall, familiar to Stargate Atlantis fans, is the communications office on Ark 04