Blind Musician

Ray Charles: one of the founding fathers of soul, and blind since the age of seven.

Music is a common career of choice for people without sight, both in real life and in the realms of fiction. In many cases, the musician's lack of vision will actually enhance his musical abilities.

Examples of Blind Musician include:

Anime and Manga

Yin from Darker than Black. Also a Blind Seer.

Film

Blind Mag from Repo! The Genetic Opera
- Though the fact she's in-universe promoted as "Blind Mag" may be a bit of a lampshade, as she's not actually blind anymore, and hasn't been for seventeen years. That's hardly a secret, either. Perhaps Gene Co itself is playing on this trope?
In Get Crazy, we meet a B.B. King expy at a fellow blues man's funeral. All the other blues men in attendance are blind, throwing flowers, well, blindly. One of them walks into an open grave.
In Suspiria, there's Daniel, the blind pianist.
In Slumdog Millionaire they blind boys who can sing because blind singers earn more.
An entire band in Hop.

Literature

Rosemary Sutcliff's historical novels use this trope often. Sometimes the blind musician, always a harper, is blind from birth, but usually, in whatever culture she's writing about, it's a custom to blind a boy found to have musical gifts, so that his gift can grow stronger and he can become the next village harper, a revered position. She does have plenty of harpers who aren't blind, too, though.
Linus Wynter from Eoin Colfer's Airman - a blind spy who etches out an entire opera on the walls of his cell.
Aurelio, the blind Manoush who first appears in City of Stars, the second book in Mary Hoffman's Stravaganza sequence.

Music / Real Life

Ray Charles
Jeff Healey
Happened a lot in blues music. Blind Willie Johnson, Blind Willie McTell, Blind Lemon Jefferson...
Stevie Wonder
The 18th-century Irish harpist/composer Turlough Carolan.
José Feliciano
Ronnie Milsap
Diane Schuur has proved that gender is no object for this trope.
Lyricist Fanny Crosby.
Terri Gibbs
The Blind Boys of Alabama
Jazz pianists George Shearing and Lennie Tristano.
Rahsaan Roland Kirk, who sometimes played two or three saxophones at once.
Art Tatum
Ken Medema
Andrea Bocelli
Blind Tom Wiggins, an enslaved autistic piano savant popular during the 19th century
Brother Ali, a blind, albino, Muslim, Caucasian rapper
One episode of Stan Lee's Superhumans featured Derek Paravicini, a blind autistic man who can remember and accurately replay any song he's ever heard in his life.
Gao Jianli, a musician during the rein of the Chinese Emperor Qin Shi Huang (259-210 BC), which means this trope is recorded to be Older Than Feudalism, no big surprise. Gao Jianli had his eyes put out by the emperor, who feared an assassination attempt but liked his music. Sure enough, Gao Jianli tried to assassinate the emperor by attacking him with his lute. Yeah. Unfortunately, he failed. But he still might also count as a Handicapped Badass despite that.

Live Action TV

One episode of Quantum Leap was about a fictional blind pianist.
The Rutles had retired New Orleans bluesman (IIRC) Blind Lemon Pie, who claimed to have invented The Rutles' music, although his wife retorted that he made this and similar claims only for the benefit of TV documentary crews.
One episode of Jonathan Creek had a musician pretending to be blind in order to enhance his reputation... not to mention using it as an excuse to feel up women because that's how he "sees" what they look like.
Jason "Jace" Newfield of the Disney Channel Original Movie Going to the Mat. Lampshaded when he expresses frustration at his lack of success on the wrestling team, saying he wanted "to be a part of one thing where [his] disability was totally irrelevant," and adds that the fact that he's a musician as well makes him a "walking cliche."

Video Games

Apollo Justice: Machi is a fake one. Lamiroir was a blind singer, but had surgery to regain her vision.
It's one of the innocent bystanders in The Punisher NES game. Killing him will remove a chunk of health from you.

Western Animation

An episode of The Simpsons also makes reference to a jazz sax player called "Blind Willie" Witherspoon. He was so good he became a jazz legend even though he'd been unwittingly playing an umbrella for the duration of his career. Nobody told him because they thought it was funny.
A Cow and Chicken episode has a blind black jazz player neighbor who lives in a swamp.
The "Toby Danger" cartoon in Freakazoid! had a brief gag where a dead ringer for Ray Charles continued performing, oblivious to the power being cut.
Toots (Joan's foster dad) from Clone High.