Dragon Age: Origins
The world is at threat from a Exclusively Evil race of subterranean monsters called Darkspawn. Every so often, the Darkspawn form armies and surge to the surface en-masse, an event known as a "Blight". In response, an elite band of warriors called the Grey Wardens was formed specifically for the purpose of fighting Darkspawn and defeating the Blight.
The story of Origins effectively consists of three parts. The first places you in the role of a newly conscripted Grey Warden as you take arms against the Fifth Blight, only to find yourself in a nasty Last of His Kind situation and tasked with uniting the fractured political landscape of Ferelden against the Darkspawn threat.
The second part unfolds in the Expansion Pack, Dragon Age: Awakening. The plot concerns the efforts of a Grey Warden (which can be the same one from Origins) to rebuild the forces of the Grey Wardens in Ferelden while dealing with the aftermath of the Fifth Blight and delving deeper into the motivations and origins of the Darkspawn.
The third part is told in the DLC "Witch Hunt", which takes place two or three years after the end of Origins. It chronicles the search for Morrigan, an enigmatic companion (and possible love interest) in Origins who disappeared after the conclusion of the Fifth Blight.
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