Gotta Kill Them All

Gotta Catch Them All with a twist. The Plot Coupons or MacGuffins in question have to be found... and then destroyed. Perhaps they are Artifacts Of Doom that menace the existence of the world as we know it, or maybe they are a group of Villains that just appeared and instead of ganging up and going against The Hero, they decide to spread and be evil elsewhere.

Many a Roaring Rampage of Revenge plot will involve the hero hunting down each bad guy on his hit-list in Gotta Kill Them All fashion and slowly working his way up to the Big Bad behind it all for the final showdown.

Compare There Can Be Only One and Shoot Everything That Moves.

Not related to Kill'Em All — directly, anyway.

Examples of Gotta Kill Them All include:

Anime and Manga

The last Story Arc in Dragonball GT has Goku and Pan looking for the Seven Dragons formed by the bad energies gathered by the Dragonballs, and they have to destroy them to purify the balls and make them usable again.
- This could have presented a bit of a problem for them when one of the "evil" Dragons turned out to actually be a fairly decent guy...but they were saved from any moral dilemma when he got defeated and absorbed by the most evil Dragon of all.
  - It may not have been a problem at all. From what I can tell, Shadow Dragons can live without Dragon Balls, they probably just get weaker or something from doing so, since that's the source of their power.
    - Funny thing is the Story Arc makes a point at the very start that the high concentrations of negative energy were destroying the planet and the shadow dragons are literally those negative energy concentrations given physical form and life. They would have to kill him sooner or later because while nuova shenron is a nice guy, he is also still a (for lack of a better term) walking bio-hazard by virtue of being a massive collection of the very energies that were currently causing the problem.
In Star Driver, Takuto's goal is to destroy all of the Glittering Crux's Cybodies so that Wako will be allowed to leave the island and fulfill her dream of becoming a pop idol in Tokyo. It Makes Sense in Context.
The Angels of Neon Genesis Evangelion: NERV's strategy is to kill them one by one as they invade.
- Not to mention that from some points of view this is the intended result of Instrumentality
  - Or in the case of the manga, a recent chapter seems to make this into Gendo's ultimate aim, regardless of what the original plan may have been.
The Poseidon saga of Saint Seiya had the heroes go and destroy 7 giant pillars below each ocean, to be able to destroy an even larger pillar in which Saori was trapped. Each pillar had a guardian of course, and 5 of those guards ended up dead.
Villainous example in D.Gray-man, where the Millennium Earl wants to destroy all Innocence. This may be made easier by the fact that one of the 109 Innocences is the Heart, which will destroy all the rest if it is destroyed.
A slight subversion of this trope is the central plot of Gash Bell. Although you don't technically kill your enemies (you just send them back to the alternate dimension where they came from), the effect is the same.
Rave Master uses this, where the group's quest is to destroy the Dark Bring (Shadow Stones).
In Bakuman｡, the main characters show their editor, Hattori, a story idea for a series about a world infested with demon dragons that has a sword with many demon dragons sealed inside. Every time one is killed, another emerges from the sword, and if the hero kills all of them without losing the sword to them, peace will be restored. Mashiro finds the story to be old-fashioned and stereotypical, but thinks it's worth showing to Hattori, and Hattori tells them they'll have to come up with a better idea than that if they want to go mainstream.
Villainous example in Naruto- the Akatsuki are seeking to collect and extract all nine tailed beasts in order to form the original ten tailed beast. The extraction process is fatal to the Jinchuriki.

Comic Books

In the X-Men novel series Time's Arrow, our heroes have to take out the Time Arrows that threaten to delete parallel universes a la DC's Crisis on Infinite Earths. Or at least that's what it's supposed to look like at first.
ROM Spaceknight was on a quest to wipe out all the Exclusively Evil Dire Wraiths in the universe... or at least banish them to Limbo. He does encounter one Wraith who did a Heel Face Turn after disguising himself as a family man and Becoming the Mask, but this Wraith gets killed by his comrades when they discover he isn't evil any more.
The Crow, in all its adaptations, sticks with the Back from the Dead version of this.
The premise of Scott Pilgrim, albeit a quirky spin on it in terms of the trope and its execution. In order to date the (literal) girl of his dreams, Scott has to defeat her League of Evil Exes. In this case, "defeat" roughly translates to "inflict bodily harm until they explode in a shower of coins".

Film

In Kind Hearts and Coronets, Louis Mazzini, illegitemate member of the D'Ascoyne family, kills off eight members of the family in order to become the Duke of D'Ascoyne. Bonus—the eight D'Ascoynes are all played by Alec Guiness!
The Immortals from Highlander. In the end, There Can Be Only One. Some, like the protagonists, are content to coexist peacefully for the time being, but the evil ones are constantly coming out of the woodwork to cause trouble.
Because Skynet has little information about Sarah Connor's 1980s whereabouts other than that she lived in Los Angeles at the time, as soon as he arrives the Terminator simply looks up "Sarah Connor" in the phone book and goes down the list killing anyone with that name - it even gets him labelled the "phone book killer" by the media.
Beatrix Kiddo of Kill Bill literally has a list.
Tombstone - After Wyatt Earp's family is attacked by the red-sash wearing Cowboys, he declares, "From now on I see a red sash, I kill the man wearing it."
If you don't kill all Gremlins, you'd better try to get them all next time they come around.
Battle Royale. Not a revenge plot, but the students definitively have to be the last one alive.
This is half the plot of Faster (The other half being those chasing Driver).
This is the basic premise of the film Kill List—two Professional Killers are given a list and contracted to kill everyone on it.

Literature

Harry's quest in Harry Potter and the Deathly Hallows have him searching for Voldemort's Horcruxes, which keep him alive while they are intact.
The Four Sisters in Deltora Quest.
The Dangerous Days Of Daniel X - The whole premise of the book series. Danny essentially has a big wanted list of alien criminals on Earth, and surprise surprise the one that killed his parents is number one on the list. The entire series basically revolves around him killing off or capturing the aliens on the list one by one, making his way to the one who killed his parents.
In The Wheel of Time, although not necessarily required, Rand & Co. are killing off the 13 Forsaken one by one since they are trying to release the Dark One.
Jack Vance's The Demon Princes quintology has the protagonist tracking down each of the 5 beings who destroyed his Doomed Hometown and enslaved all the survivors except for him and his grandfather.
In A Madness of Angels, each section of the book consists of Matthew tracking down and killing or defeating the head of one of the subsidiaries of the Tower, until the climactic scene where he fights the head of the Tower itself. More or less.
In the original novel Dracula, the vampire hunters have to track down and destroy the 50 boxes of earth Dracula transported to London from Transylvania and scattered throughout the city so that he will have no safe haven to go to when the sun rises or to change his shape.
In the Star Trek Deep Space Nine Relaunch novels, Iliana Ghemor is on a mission to kill every version of Kira Nerys in the multiverse .

“I don’t fault you for not seeing the big picture, Captain. After what was done to me, it took me a while to understand what I needed to do so that I could be whole again. But when I meet the Prophets, they’ll see inside me, just as they did with your Emissary. They’ll understand what I need to get my life back. And I’ll use the Soul Key to find every other Kira that has laid claim to a piece of my soul”.

In The Hunger Games, 24 children are pitted into an arena to fight to the death. Throughout the book, the main character frequently recounts how many children are left to compete with.

Live Action TV

Sylar to other superpowered people in Heroes, although it's more like a combination of both this and Gotta Catch Them All.
- And in season 2, Adam Monroe targets the original founders of the Company as part of a Roaring Rampage of Revenge.
Uther's Roaring Rampage of Revenge against magic users in Merlin probably counts.
Kamen Rider Decade has the titular hero being told that, in order to avert the collapse of The Multiverse, he has to travel to the realities of the last nine Kamen Rider series and kill all of the heroes. He refuses, of course, and helps the Riders. It turns out that the collapse proceeded apace, accelerated by the villains but inevitable with or without them. When Decade was provoked into going to his Super-Powered Evil Side, slaughtering all Riders as Decade Fury, the worlds, no longer being forced together by the Riders' powers, were all restored to their original states - including the slain Riders. It turned out plan A was the right one and Everybody Lives in the end.
The nineties show Brimstone features a policeman brought back from hell (it's complicated) by the devil to return a number of escapees to hell the hard way (killing them, though the vast majority are only vulnerable in the eyes.)
Alya's list on Game of Thrones; not a physical list, but one she recites every night before sleeping to remember the names. All names on the list are people who committed some sort of severe crime against her family. A grand total of 13 intended victims have been on the list at one time or another; four of them she deleted after forgiving the crime, six are dead (two by someone other than Anya) and one deleted because she believes him to be dead. (Maybe. The Hound survived, and she specifically said she wanted him to suffer.) As of the second to last episode of Season 8, every victim on the list is dead, and Alya - who survived the Final Battle no longer needs it.

Tabletop Games

In FASA's Earthdawn, in order to kill a Horror one must first kill its physical body, then travel to the astral plane and kill its astral body.
- Not quite the case; depending on the Horror, you might only need to be a Badass Normal fighter and kill it physically like any other critter. Other Horrors on the weaker end of things only exist on the astral plane, and therefore can only be killed there. Only the REALLY BAD Horrors (i.e.: the more powerful Named ones that will quite happily kill your party with ease if you bump into one of them) must indeed be killed on both planes of existence to be declared Deader Than Dead.
The ultimate goal of the Necrons in Warhammer 40,000: by exterminating all life (including bacteria), they close off the Warp (an alternate dimension essentially made of emotion), pretty much the only power that can stop them. Fortunately, most of the Necrons are still dormant.

Video Games

The Colossi in Shadow of the Colossus.
The evil path in Knights of the Old Republic 2 is hunting down and assassinating what is left of the Jedi Council.
The four elemental Fiends from the first Final Fantasy game.
- And the ninth.
- Also, a sidequest involving the eight dragons in the sixth, and the advanced versions in the Updated Rerelease.
The various Metroid evolutions in Metroid 2: The Return Of Samus.
- And, consequentially, the various forms of X in Metroid Fusion.
The initial goal of SEES in Persona 3 is to defeat the twelve Full Moon Shadows that have been popping up ever since the protagonist first joined the party. Unfortunately, in doing so, they release the herald of Nyx, the Anthropomorphic Personification of death, who had been split in twelve by Aigis and sealed inside the protagonist ten years ago.
The members of the United Assassins Association in No More Heroes. As the main character, Travis has to murder the top ten ranked assassins in the nation, one by one, to rise through the ranks and gain the top spot for himself.
Most of the NES and SNES Mega Man games have the titular character hunting down Robot Masters to take their powers and eventually fight their evil master, Dr. Wily himself.
In Sonic Adventure 1, E-102 Gamma's story following his rebellion against Robotnik is to find and "liberate" his fellow E-100 series robots. "Liberate" in quotes because he destroys them and frees the captured animal powering them. The last one to die is, of course, Gamma himself.
Halfway through Seiken Densetsu 3, the eight God Beasts are released into the world, and the heroes are forced to go out and slay each one of them. Of course, that just plays straight into the villain's plan.
The six dragons in Chrono Cross. Well, you can get by without beating the Black Dragon, but that's only if you fail to do it the right way.
To some extent, the four sentinels in Wild ARMs 5. They're guarding four towers that have to be destroyed before you can fight the Big Bad Volsung.
Magical Girl Lyrical Nanoha A's Portable: The Battle of Aces has the Dark Pieces and Materials, beings formed from the remnants of the Darkness of the Book of Darkness that must be taken down lest the Darkness of the Book of Darkness return.
Though you don't actually kill them, the whole point of the main series Pokémon games is to defeat the Gym Leaders in each city by knocking out their Pokémon, so you can defeat the Elite Four and subsequently, the regional Champion. The Frontier Brains can qualify as Bonus Bosses in regard to this goal, though.
The Desert Treasure Quest in RuneScape involves running around the whole continent and defeating four guardians who hold four diamonds you need to access an ancient pyramid, where the eponymous treasure is located.
The "Gnomes Are Evil!" sidequest in Fable 3. Due to a magical spell gone wrong, 50 garden gnomes were given sentience and then teleported all over Albion. You have to hunt them down and shoot them, which transports them back to their owner. Fortunately the gnomes are foul-mouthed, annoying little jerks.
- Fable 2 is similar, with 50 foul-mouthed stone gargoyles who you must shoot.
The Assassin's Creed series basically embodies this trope. From the main plot of all three games revolving around assassinating a group of villains, to the optional sidequest of killing the 60 Templar Knights in the 1st game.
The Gold Skulltulas in The Legend of Zelda: Ocarina of Time. Good luck finding the whole hundred of them. Also doubles as Gotta Catch Them All as you must collect all the tokens they drop as well.
- To a greater extent, in Majora's Mask, you have to destroy the guardians of all four Termina temples to free the Giants.
- Twilight Princess has 60 Poe souls for you to collect in a side quest by killing Poes. They're pretty much everywhere and some are only visible at night. Happy ghost hunting!
The goal of Crackdown is simply to kill about 20 different gang bosses, and a skilled player could simply charge off and get to work immediately upon starting a new game. Of course, leveling up your skills and finding new weapons will help out a lot.
If one goes through the Ruling End of Hyperdimension Neptunia mk2, one must kill ALL the other goddesses just to power up a sword to finally kill Magiquone. However, it fails.
Going for 100% Completion in Grand Theft Auto IV? Among other things, you'll need to kill all ten most wanted criminals on each island (Broker/Dukes, Algonquin, Alderney), and you'll also need to kill all two hundred pigeons scattered across Liberty City.
Pretty much the main objective of Arena mode in Team Fortress 2, your team's goal is to kill everyone on the opposing team while they try to do the same to you. Whichever team still has at least one player standing at the end wins.
Half-Life 2 has an achievement where you need to kill 333 Antlion grubs. It's easily the most infuriating achievement in the game.
In Dark Souls, the player needs to collect the remaining Lord Souls to open the way to the First Flame. How do you get the Lord Souls? By killing the Badass gods you see in the Action Prologue.

Webcomics

Othar Tryggvassen, Gentleman Adventurer! from Girl Genius has this as his primary goal concerning sparks. Yes, including himself (last).
Elven Lacryment. The lead character is on a quest to rid the world of the orcs that destroyed her village.

Web Original

The Dark Generals in Sailor Nothing.
The Holders Series - of course, it's a tossup as to whether the results of bringing them together or preventing them coming together are worse, and if they are all destroyed they will "unite in the destroyed state", so it's rather a no-win situation.

Western Animation

In the second season of the Harley Quinn series, Harley keeps a "Kill Board" where she keeps pictures of Gotham villains she plans revenge on: Joker, Penguin, Riddler, Two-Face, Mr. Freeze, and Bane. Although, as Poison Ivy reminds her, the Joker is presumed dead and Penguin is definitely dead even before she puts it up. Although, while she calls it a "Kill Board", she seems open to ideas other than murder to gain revenge, as the Riddler found out when they put him in his own human hamster wheel to power their generator.

Real Life

Antibiotics and pesticides: The danger of bacteria and pests developing immunity to chemicals make it important that these chemicals be used sparingly, but when they are used, they should be used in sufficient amounts and for sufficient durations that the pests are truly wiped out.
Vaccines: Same as above, the ultimate finish line would be the complete erradication of a/all disease. Still a long way to go but making progress.
This regularly happened on Pacific islands in World War 2. Not only would Japanese refuse to surrender but even the wounded would clasp grenades forcing victors to dispatch them as they passed in self-defense. On Saipan it got so bad that the garrison was slaughtering their own civilians or pressuring them into suicide right in front of the Americans. Even hardened troops were sometimes horrified by how far they would take it and not just because it increased their personal danger.
- While Hitler wanted Germans to behave that way(of course HE would), this was more intermittent in Europe. Still the SS were known for that and would sometimes force other Germans to follow along with them even toward the end of the war when most wanted to give up. As in the Pacific there were some cases where there was no choice but to kill them all.