Paranoia Fuel/Web Comics

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In an episode of the Parking Lot is Full you are informed that you are one of only 23 real people in the world and everyone else is a fake, designed to keep you from the others. Taken to logical conclusions, this becomes even more terrifying. Everyone in your life, everyone you love, hate, talk to, work for, even all the tropers here are designed by some malignant force to keep you from making a genuine connection with one of the few other 'real people'.
For the 2007 Crossover Wars event, a fake comic was created as the birthplace of Villain Henchman Max Catnap, a cat furry with a disturbing hatred of his own kind. The fake comic's progression from crayon-drawn, innocently well-intended furry fare to brutal murder is enhanced by Max's erasing of himself from the archives, revealing the full story only in flashbacks.
This Saturday Morning Breakfast Cereal comic sums up this trope very well.
The recent Freefall arc in which Florence's short-term memory is impaired as part of an effort to check on her mind, since she's technically an artificial intelligence.
From Brawl in the Family : Peppy is EVERYWHERE.
- This strip puts a whole new spin on the Mushroom Kingdom.
In Homestuck, John and Rose (and possibly Dave) all have Rooms Full Of Crazy without them realising it for most of the plot so far. Apparently, the explanation is that they unconciously scribble on their walls and then their mind just filters out so they never notice it. Now look around the room that you're sitting in and think about what your subconcious mind has written...
- Draconic Dignitary is watching you.
- The narration starts to get a little bit too self-aware in act 5.

You suddenly wonder where Jadesprite went. You wonder that because I said you did. I know where she went.

- Are you next?
- Karkat: Highlight Don't turn your back on the body.
- S u c k e r s .
- The Alpha universe. They Live!.
- Lord English is behind the Fourth Wall. No one is safe.
This is what you get when everyone you've ever respected or cared about has conspired to hide your true identity from you your entire life. Strange things happen at Gunnerkrigg Court all the time, but Annie didn't see that coming.
Natalie Geln knows where you live...