Perfect Blue/Tear Jerker

Believe it or not, this troper cried during the climax of Perfect Blue, when Rumi/Mima's Evil Twin was trying to kill Mima. Not because there was anything sad about it, but because at that point, the insanity was too much, especially to the overly-curious 16-year-old I was back then. I know, the insanity of that part wasn't as bad as the forces of Chaos, but it was pretty up there.
- "I guess I went to Harajuku today..." turned this troper's face into a heap of snotty mush, because it signifies Mima's absolute lowest point in terms of sanity - she doesn't trust her own perceptions at all any more (although, who can blame her? It's a Kon-sensei movie). Conversely, Mima's climactic cry of "Like I even care! I AM MYSELF!" was a thing of beauty that made this troper weep with joy.
  - What makes these moments more tear-jerking is that the movie is a rather disturbing example of Break the Cutie. In the first half of the movie, Mima is a very nice and pleasant lady (albeit a little ditzy), and I don't know if it was just in the English dub or not, but she only swore once in the whole movie even while the other characters were cursing like sailors. Plus she's kind of hot, especially in that costume she wore for the concert. I'd go out with her (if she weren't a fictional character, that is).
This troper felt sorry for MeMania. Yes, he was a serial killer and attempted rapist... But that's because he was a deformed, barely-functioning schizophrenic who lived only for his perfect image of Mima. The scene where we see his apartment is an enormous Stalker Shrine and that all he wants in life is "the real Mima's" affection was genuinely sad.
When Mima comes home and all of her pet fish are llying near the bottom of her aquarium, dead. She just stares at them in shock for a few seconds then tears up and proceeds to trash her room.