Shameless/Funny

"He seems nice" Karens first impression of Ian.
"We've been burgled- someone's nicked me Grandma!" (After Carl and Marty's Zany Scheme involving burgling some burglars went wrong. They stole an urn, under the impression that it was a football trophy)
Mimi Maguire forcing her way upstairs in series 3, with the Gallaghers trying to hold her back by throwing furniture at her. One of them resorted to Looney Tunes tactics and stuck a child's rubber ring over her head.
Every other scene with Kev and Veronica.
Every other scene with Micky Maguire.

Frank blinding his eye with a Luger pistol after loading it with the wrong bullet.
Lucy Jo chasing Fiona down the street with a baseball bat in one hand and her baby in the other.
- Fiona later telling her to just beat her with the damn bat.
From "A Bottle of Jean Nate", Kevin getting high on cocaine and Jody's crying after sex and listening to Kiss From A Rose by Seal during sex.
Estefania kicking Lip in the back of the head while having wild sex with Marco in the back seat of Steve's car, who is her husband, until Lip just straight up leaves.
The glorious Mood Whiplash of seeing a bare-ass naked Marco pinning Steve to the floor with his foot, with a corkscrew in his ass, right after Lip gives an emotional goodbye video message to his child.
Carl kills a bald eagle so the family decides to have it for Thanksgiving and save the turkey for later. After finding out how illegal what they doign is, they quickly dispose of the tracker the bird has attached to its leg.
"I reloaded. .Twice."