NEO-TOKYO IS ABOUT TO EXPLODE
Akira (sometimes spelled AKIRA to differentiate between the work and the title character) is the name of a post apocalyptic sci-fi manga first released in 1980 and its movie adaption released in 1988. It is the most recognizable of Katsuhiro Otomo's works.
In July of 1988 (or at 2:17 P.M. on December 6th, 1992), a mysterious black-domed explosion destroys Tokyo and sets off World War III. Thirty-one (or thirty-eight, depending on whether it's the manga or the film you're dealing with) years later, the rebuilt city, now known as "Neo Tokyo" has fallen into decay.
Two rival biker gangs, the Capsules and the Clowns, are having a turf war one night, when one of the youngest Capsule members, Tetsuo, almost literally runs into an escaped government test subject. Moments later, the test subject is taken back into custody by the army. However, they also decide to take Tetsuo with them. He then becomes the newest test subject for the "Akira Project." But when Tetsuo's powers awaken, the combination of an inferiority complex harbored since childhood with power beyond Tetsuo's wildest dreams waste no time in driving him insane. He escapes the lab and goes on a super-powered rampage through Neo Tokyo, killing and destroying everything in his path. It falls to a handful of people, including Capsule leader and Tetsuo's friend Kaneda, to put a stop to the destruction.