Do you think you could add this example as an extension of Double's entry?:
"Mention also goes to the titular Skullgirls themselves. They are the result of an Artifact of Doom known as the Skull Heart transforming women who use it to make ill-considered wishes. And since it sees all wishes to be ill-considered by nature, it will transform them no matter what they wish for. Bloody Marie, the current Skullgirl, looks fairly normal (aside from her deathly pale skin, exposed rib-cage, creepy monotone, white hair and glowing red eyes that form skull-shaped irises, that is) until she is greatly threatened, at which point she transforms into a hideous mass of bones."