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This type of one-shot (no pun intended) drug use is far more likely to cause [[Hilarity Ensues|Hilarity]] than to be used in the service of a [[Drugs Are Bad]] aesop. If there's a [[Will They or Won't They?]] situation already established between two characters, the writers may be tempted to bring in [[Kissing Under the Influence]].
See also [[I Can't Believe It's Not Heroin!|I Can't Believe It's Not Heroin]]. If the substance in question goes beyond altering behavior and causes the characters to hallucinate, it's a [[Mushroom Samba]]. If the character passes out immediately afterwards, it's a [[Non Sequitur Thud]]. Sometimes Intoxication Ensues from a [[G-Rated Drug]]. If ''most'' of the cast are affected, this becomes [[Everybody Must Get Stoned]] - and if that leads to romance, it's [[Love Is in
The alcoholic subtrope is [[Unsuspectingly Soused]].
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== Anime and Manga ==
* In the manga & anime of ''[[Ah!
* This happens to Usagi twice in ''[[Sailor Moon]]'', in both cases she mixes up alcohol with juice. First in the first season in an episode based directly on a manga chapter she winds up [[Kissing Under the Influence]] [[What the Hell, Hero?|(bad Mamoru!)]]; and a second time in the third (S) where it's actually much funnier. In the second case she goes completely la-la and starts speaking gibberish in both Japanese and English at swanky party, the (English) guests find her delightful.
{{quote| '''Usagi:''' ''(butting into a discussion on the theory of relativity)'' The pudding of relativity? Let's see... Well, in other words, you take milk, eggs and sugar, and stir it all up. Then you put a lid on it, and for about 30 minutes, you steam it... Oh! And if you forget the whipped cream, you're no good as a woman. Yeah.}}
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* In ''[[Hidamari Sketch]]'', Hiro wrongly bought alcoholic juice at Yuno and Miyako's welcoming party, and the two freshmen got drunk. While Miyako is still [[Cloudcuckoolander|herself]], the generally innocent Yuno started ranting about [[It Just Bugs Me|It Just Bugs Me's]]... and Sae uttering an [[Engaging Conversation]] even she [[Ship Tease|was not drunk]]...
* Rock Lee's sake induced drunken kung fu in ''[[Naruto]]''.
* In ''[[
** Not helped at all by Akio finding the whole situation hilarious, and going out of his way to make it worse.
*** Until Sanae cheerfully tells him that she wasn't entirely joking about her attraction to Tomoya. He didn't find it so amusing after that.
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* In the first ''[[Dragonball Z]]'' Deadzone movie, Gohan eats a delicious looking apple from Garlic Jr.'s personal orchard. Turns out that "Children mustn't eat those". Cue the [[Mushroom Samba|drug trip montage]].
* ''[[Seto no Hanayome]]'' has all the female cast and Saru drinking Uoihatsu, a mermaid drink that makes a person "act on their instincts". This leads to a group of drunken junior high schoolers running around a movie set, and hilarity ensues.
* ''[[
** This is actually "Suppi-chan's" ''normal'' reaction to anything that has sugar with it, and the reason that he's not allowed sweets. Nakuru and Kero-chan, both lovers of all things sugary, find it utterly hilarious when they're not the targets of the resulting mouth lasers.
* ''[[Genshiken]]'' has a "New Member Party" in the first season, where one potential member gets soused and wanders the restaurant signing the theme song from [[Show Within a Show|''Kujibiki Unbalance'']] loudly. Granted, his character type is one that may do things like that anyway, regardless of alchohol consumption or public exposure.
* In one episode of [[Inuyasha]], the party is exposed to an alcoholic vapor which intoxicates those who breathe it. Several members of the party cannot [[Can't Hold His Liquor|hold their liquor]], apparently. Sango, in particular, starts behaving in a [[Mad Love|very]] [[Almost Kiss|interesting]] way towards Inuyasha. Cue the cries of "[[Restraining Bolt|Sit!]]"
* ''[[To Love Ru]]'' OAV 5 has all the harem acting this trope out, except Rito, who's trying to figure out why they're acting like they are.
* A chapter of ''[[
* In [[Detective Conan]] Heiji gives Conan some chinese wine as a medicine, and is scolded by Ran when he becomes totally wasted. Made funnier in the dub because Conan starts hitting on Ran.
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{{quote| '''Superman''': Wait, do you smell that? Somebody's making ''brownies''. *''Runs to the window and looks out across the vast gulf of space between the Watchtower and Earth''* Yes! Brownies! In ''North Dakota!'' We have to go to North Dakota. ''Right. Now.'' ([http://asylums.insanejournal.com/scans_daily/1073332.html here is a LJ post of the comic])}}
* In Jeff Smith's ''[[Bone]]'', Thorn and Fone Bone get tipsy from hiding in the woods and eating nothing but berries. The berries could have fermented. This happens in [[Real Life]], and birds get drunk from the juice and fly into things. [[Hilarity Ensues]]
* A drug which does this appears in the early ''[[Tintin
* In ''[[Dork Tower]]'', this happens to Ken after he tries one of Igor's sugar-overloaded "[http://www.dorkstock.com/IgorBars.html Igor bars]". He passes out four seconds later...
* In [[Stone Soup]], the eldest daughter tastes parts of the batter for a cake her grandma was making for the holidays. She then proceeds to slur her words (more specifically, she starts slurring "few"), with the grandmother being unaware until after she starts slurring. Then it cuts to the grandmother's daughters expressing shock that the grandmother let the eldest granddaughter taste the batter for the rum cake she was making, and wondered how much she ended up tasting as the grandmother looks sheepishly while the granddaughter is stating she loves her grandma in a very loopy manner.
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* A ''[[Yu Yu Hakusho]]'' fanfic ''Purple High'' is entirely this, when Kurama attempted to breed a Makai plant capable of curing burn wounds, and instead creates a powerful hallucinogen that, among other things, prompts Kurama to reveal his stash of green spandex, gives Hiei the munchies, compels Botan to prostrate herself before Kurama to learn his hair-care techniques, and turns Yukina into an [[Ax Crazy]], [[Cloudcuckoolander]] [[Card-Carrying Villain]].
* The [[DC Nation]] plot "The Lotus Eaters," the Titans come to a planet used as a place of healing and vacation spot for Tamaranians when Starfire fails to check in. While [[Government Drug Enforcement|it turns out Blackfire sent some mercs to turn the place into a soma factory]], a snoot-ful of the toxin in question sends Gar and Kon into giggly, happy drunk territory, complete with the "I love you man." Best line ever from Superboy when Beast Boy changes into a squid, "I am NOT a Japanese Schoolgirl!"
* In the ''[[X
* In the [[Yu-Gi-Oh!:
* A ''[[Kirby]]'' fanfic, ''[[
== Film ==
* Alan Tudyk's character in ''[[Death
* ''[[Joe Dirt]]'': Joe gets the idea to ask a police sketch artist to make a portrait of his missing parents. He raises the money, but... "Somethin' happened to my head. See, I spent the night in what I ''thought'' was an abandoned circus tent... I guess there was no circus." Cue the gibberish singing and crazy nudity as Joe is whacked out on bug bombs. Needless to say, this throws off the sketch artist considerably.
* In ''Dick'', the two [[The Ditz|air-headed]] female leads, who are working as White House interns during the Nixon administration, use their older brother's "secret ingredient" - which they don't realize is marijuana - when making brownies. Nixon loves the brownies and serves them during an important meeting with officials from the Soviet Union. (It goes rather well.)
** Not just officials -- his famous summit with Russian Premier Leonid Brezhnev is a success thanks to this trope.
* Subverted in ''[[
* In ''[[Bad Boys]] II'', Marcus accidentally ingests Ecstasy, and starts acting weirdly - just as he and Mike get to their boss' house to report progresses in investigation...
* ''I love you Alice B. Toklas'': She had a freaky cookbook.
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Su-Chin: "I heard that was you." }}
* In ''Saving Grace'' the two old ladies who run the village store are told that a marijuana plant is an exotic tea. They steal a few leaves and brew them up so they can taste this new tea. They proceed to get stoned, much to the bewilderment of their customers. <ref>THC not being water soluble, this must be tea with milk.</ref>
* [[Harry Potter (
** What about Ron after he ate chocolates filled with a love potion?
* ''[[The Hangover]]'' starts out this way. The majority of the movie is the protagonists trying to unravel the resulting [[Noodle Incident]].
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* In [[Charlie Chaplin]]'s short film ''The Cure'', the protagonist has gone to a health spring resort to cure himself of alcoholism. The management finds his secret stash of alcohol and gets rid of it . . . by throwing it out the window, and right into the health spring. A wild party ensues.
* In Chaplin's ''[[Modern Times]]'', he mistakes cocaine for salt and ingests a generous dose. In the ensuing frenzy he ends up foiling a prison break and is hailed as a hero.
* In ''[[Transformers (
* In ''Them Thar Hills'', [[Laurel and Hardy]] take a trailer to the country for health reasons, and camp out by a well that's just been used as a moonshine dump. They attribute the funny taste of the water to healthy minerals. Soon they're snockered along with a young lady who's staying with them while her husband looks for gasoline. [[Hilarity Ensues]] Then, in ''Blotto'' it's subverted when they set out to get drunk, and get giddy, silly, and maudlin, before finding out their wives had switched their hooch with a nonalcoholic substitute.
* In ''[[Taking Woodstock]]'', the transvestite security guard arrives with hash brownies. Elliot figures it out, and doesn't eat one. However, his stodgy parents take his angry suggestion to eat a brownie or two, and end up dancing in the rain.
* In the vampire spoof ''[[Love
* In ''[[
* In ''[[Bon Cop, Bad Cop]]'', our heroes barely escape from a house that was set on fire by a booby trap in the marijuana farm in the basement. Once they get out, catch their breath, and look on the destruction, they start giggling uncontrollably, and continue to do so through the entire next scene as [[Da Chief]] chews them out for burning down said house.
* In ''[[Young Guns]]'', When Chavez gets the other main characters to drink Peyote to get them in touch with the "spirit world", they start talking in slow motion and keep seeing chickens. This also leads into a hilarious scene where they ride through an Indian settlement, high as a kite.
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* A [[Running Gag]] throughout ''[[The Areas of My Expertise]]'' is "getting either very high or very autistic".
* ''[[I, Claudius]]'' has a rare serious version where after Claudius finds out that his wife Messalina has been cuckolding him (something everyone else in Rome has known for years) and that she is on the verge of having him overthrown, his [[Evil Chancellor|evil]] [[Poisonous Friend|but loyal chancellor]] gives him some drug which is supposed to calm his nerves. While on the substance, Claudius experiences delusions of grandeur and is able to calmly sign the death warrants of Messalina and the other 500 people at a party she held when plotting treason, something he would have been too kindly to do with a clear head.
* [[Neil Gaiman]]'s ''[[Neverwhere]]'' has a scene where Richard and Door drink some wine from Atlantis: apparently, when wine ages, it gets more potent. Richard gets tipsy on the way out and wonders if Door wants him to [[Kissing Under the Influence|kiss her]]. Thankfully, he doesn't go for it.
* In ''[[
* In [[
* Max on Valium, from ''[[Maximum Ride]]''. She has to get drugged up {{spoiler|to get rid of the chip in her arm}}. [[Hilarity Ensues]].
{{quote| "I love you! I love you sooo much!!!"}}
* In ''[[Harry Potter]] and the Order of the Phoenix'', Ron gets hit with a curse that makes him silly for a time. Later, in ''[[Harry Potter]] and the Half Blood Prince.'' Ron accidentally consumes an entire box of sweets dosed with a powerful love potion (originally meant for Harry.)
** The curse is a bit of [[Fridge Horror]]. Between his incoherency and the fact that blood was coming out of his mouth, it was implied that his loopy behavior might have been caused by internal bleeding.
* In one of [[
* In [[David Foster Wallace]]'s ''[[Infinite Jest]]'', one of Michael Pemulis' favorite methods of revenge ([[Best Served Cold|served pleasantly chilled]]) is spiking your drink with something mind-altering. Preferably a psychedelic or deliriant.
* The fandom isn't sure ''just'' what happened in the ''[[
* In ''[[The Wise
* In ''[[Hilary Tamar|The Shortest Way To Hades]]'' by Sarah Caudwell, Julia and Selena eat pot-laced fudge while at [[A Party - Also Known
* In the first book of ''[[The Dresden Files]]'', Harry is in his apartment when his love interest, Susan shows up, followed shortly by a demon set on killing him. Harry tells Susan to go into the basement and drink an escape potion while he deals with the demon...only to find out shortly after that she accidentally drank the "super tequila" love potion he had brewed earlier instead.
* Happens to ''Obi-Wan Kenobi'', of all people, in the [[Star Wars Expanded Universe]] novel [[Labyrinth Of Evil]]. He inhales Neimoidian spores and proceeds to demolish a squad of battle droids [[What Do You Mean It's Not Awesome?|while stoned out of his mind]]. (This is the "business on Cato Neimodia" Obi-Wan is so embarrassed about in Episode III.)
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** Another episode had Maya accidentally get high off of Nina's nicotine patch when she mistakes it for a Band-Aid. Another episode had the office being bombed for bugs while Nina was still inside, causing the letter she was writing in voice over to descend into gibberish.
* In the episode "Vital Signs" on [[White Collar]], the usually composed Neal is drugged after [[It Makes Sense in Context|breaking into a medical clinic]], and ends up singing Frank Sinatra, confessing to past crimes, and just acting [[Crowning Moment of Funny|high as a kite in general]]. Peter is not amused.
* ''[[
* On ''[[I Love Lucy]]'', Lucy does a commercial for health tonic Vitameatavegamin, which, unknown to her, is 23% alcohol. The director keeps asking her to do extra takes, and each time, Lucy takes a <s>shot</s> tablespoonful to demonstrate that it tastes "Just like candy". This results in her becoming drunk and making increasingly comedic bloopers. Possibly the [[Trope Makers|first example]] of the trope.
* ''[[Seinfeld]]'', Elaine takes too many pain pills, laughs at everything, yells "[[A Streetcar Named Desire|Stella!]]" a lot.
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** Also, when Booth hurts his back in "The Princess and the Pear," Vicodin "makes the furniture feel friendly"
* President Bartlet on ''[[The West Wing]]'' complains in a first-season episode that his back medication makes him loopy...and is proven right, as when on the painkillers (two different opiates) at the end of the episode, he spaces out, confuses the names of his staff, and announces -- with all the gravitas of the President of the United States -- that he's been seriously thinking about getting a dog.
* In ''[[Malcolm in
* In the ''[[
* On one episode of ''[[WWE]] Smackdown!'', John Bradshaw Layfield accidentally shot himself with a tranquilizer dart he had intended to use on The Big Show. While high on tranquilizers, he came out to the ring in a jacket, tie, and boxer shorts, and cut an extremely surreal promo, in which he beat up an inflatable dinosaur, claiming it was Godzilla, and commented repeatedly that The Big Show "eats pizza".
* Spike, in his first appearance in ''[[Buffy the Vampire Slayer]]'', recounts an incident where he "fed off a flower person" at Woodstock. ("...and I spent the next four hours watching my hand move.") Vampires in the Buffyverse are especially susceptible to unwittingly taking drugs by drinking the blood of users, and one episode depicts a designer drug meant to be shared by a human and a vampire.
* In a darker inversion, a lonely movie star on season one of ''[[
* The first episode of ''Walking With Beasts'' has some proto-horses getting drunk off fermented berries. Their reflexes are so dulled by this that one of them gets eaten by a [[Feathered Fiend|bird]].
* In an episode of ''[[The Naked Brothers Band]]'', Nat acts like this after going to the dentist.
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** In the episode "Reverend Jim: A Space Odyssey", Jim slips a tranquilizer (or at least something that is ''not'' a Chiclet) into Louie's coffee while the others are trying to figure out how to get Jim a job at the taxi company. It takes effect almost immediately, causing Louie to act significantly nicer than he usually is, start singing, pass out on the hood of one of the taxis, ''and'' agree to giving Jim a job when Bobby asks him.
** In a third episode, Alex is given some uppers and told that they are a headache remedy. He is then summoned to see the boss to explain a minor accident he had been involved in earlier while talking a million miles an hour.
* In the ''[[
{{quote| '''Jayne:''' Now we're finishing this deal, and then maybe, ''maybe'' we'll come back for those morons... got themselves caught... and you can't change that by getting all... bendy.<br />
'''Wash:''' All what?<br />
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** Another episode, "The Big Lock-Out" has Manny trapped in the bookstore with nothing but a bottle of Absinthe, which he drinks and in the ensuing dementia roasts and eats the bees he finds on the windowsill.
** In the first episode, Manny, as well as excessive amounts of espresso, accidentally swallows ''The Little Book of Calm'', making him into a sort of stoned, platitude-spouting, Zen... thing.
* In one episode of ''[[House (TV series)|House]]'', House slips a little something in Wilson's coffee...
{{quote| '''Wilson''': I'm not on antidepressants, [[Memetic Mutation|I'm on]] ''[[Memetic Mutation|speeeeeeeeeed]]''!}}
** Milder versions occur all the time on this show, especially with House himself, who at one point takes Methadone for his pain and nearly dies when he falls asleep. One moment he's cheery, the next he's at death's door. Another possible example is when too much Vicodin {{spoiler|causes House to have a powerful halluciation of now-dead Amber, as well as imagining an entire day of Vicodin withdrawal followed by sex with Cuddy. When he realizes it was all just a hallucination, he's so freaked out he voluntarily goes to rehab}}.
** A recent episode had Parks and Taub going to a patient's home to see what was wrong with him. Parks has some ice cream which was laced with LSD. The resulting acid trip is hilarious.
* In an episode of ''[[
* Appears in the "Who can keep a dead octopus on their head the longest?" episode of ''[[Kenny vs. Spenny]]'', only enhancing the weirdness already present in the challenge.
* In the episode of ''[[Arrested Development (TV series)|Arrested Development]]'' called "Afternoon Delight", Michael asks Oscar to give Lucille some "afternoon delight" so she wouldn't be stressed out. While the delight in question is sex, Oscar thinks he talks about marijuana, and gives her some marijuana-laced brownies. Later, completely stoned, she drives to Balboa Island in her car, runs over Tobias without realizing it, and crashes the car into the Frozen Banana stand.
* In ''[[Dollhouse]]'', episode 7 - "Echoes" - a hallucinogen that is transmitted by touch wreaks havoc on the dignities of several Dollhouse security guys as well as Ms. Dewitt and Topher.
* ''The Knights of Prosperity'' didn't last long, but lasted long enough to follow this trope. One episode had the Knights getting stuck in a panic room. Esperanza, who's claustrophobic, takes some medication and subsequently becomes very loopy. Louis observes "I think she took more than the recommended dosage."
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* In an episode of ''[[The Closer]]'', Brenda's niece, visiting for a few weeks as a "straighten up and fly right" experiment on the part of her parents, receives a "package" from a friend back home, which she bakes into brownies. When Brenda comes back, her impeccable nose for all things sweet conspires with her sweet tooth to lead her to the brownies in the niece's room. Brenda eats three, and while she appears to have a wonderful time, her husband Fritz was ''not'' amused when he returned.
* In a third-season episode of ''[[Kingdom]]'', the title character, Peter Kingdom, eats an omelet containing some special mushrooms. It's doubly funny because it's [[Stephen Fry]].
* Carlton experiences this in an episode of ''[[The Fresh Prince of Bel
* ''[[Drop the Dead Donkey]]''. Damien [http://www.youtube.com/watch?v=hgwvuLg7jOU gets high while reporting] on soldiers burning a huge pile of confiscated marijuania.
* One of the best examples happened in the Australian show ''[[Frontline]]'', in the episode "My Generation". Mike, the host, has a headache, and when Shelley the receptionist looks for some Panadol for him, she finds the ecstasy tablets Marty confiscated from one of the camera dudes. The ending is ''hilarious''.
* The female alien protagonist in the short-lived series ''Something is Out There'' has this reaction to caffeine. Later she's smart enough to ask for decaf, but on one occasion the coffee shop attendent has run out, so he secretly gives her the normal stuff, which causes problems as she's talking to a [[Serial Killer]] at the time.
* ''[[The X
{{quote| '''Langley''': So what killed him?<br />
'''Scully''': In my professional opinion? Beeeeeeeeeeep, crash! }}
** The episode [[Rashomon Style|Bad]] [[Our Vampires Are Different|Blood]] featured a drugged Mulder [[Crowning Moment of Funny|singing the theme from "Shaft"]].
* Several instances from ''[[The Big Bang Theory]]''
** Leonard, Raj and Howard are camping out to observe the Leonid meteor shower when they eat some cookies from what Howard claims are two old schoolteachers (the schoolteachers in questions are implied to be old enough to be going to a [[
*** In the same episode, Penny dislocates her shoulder and ends up on strong painkillers, eventually forcing Sheldon to sing "Soft Kitty" [[Crowning Moment of Funny|as a round]]
** Another example is Sheldon under the influence of Valium. [[Crowning Moment of Funny|"I'm Batman! Shhh!"]]
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** "''I'm'' not the one who stabbed the captain with a pickle!"
** And later, when Elliot {{spoiler|fakes mushroom intoxication in court}}: "It's so hot in here. I didn't order that pizza. I'm not even a fan of anchovies!"
* After [[3rd Rock
{{quote| '''TOMMY:''' So how was work today, Dick?<br />
'''DICK:''' (stoned) Oh, just fine.<br />
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* One episode of ''[[Stargate Atlantis]]'' has Rodney injecting himself with a massive dose of [[Psycho Serum|Wraith enzyme]] to take out his guards and escape. [http://www.youtube.com/watch?v=8V_k66CEap0 Once he gets home however...]
* This seems to happen ''a lot'' on ''[[Party Down]]''. There's Roman high on weed brownies, Lydia accidentally powdering her nose with cocaine, Ron downing a bottle of Henry's Vicodin, Ron high on marijuanu fumes while spending time with rappers, Bobbie on 'shrooms, Constance... on various drugs pretty much all of the time...
* Happens in the second-season finale of ''[[
{{quote| '''Stark:''' Thaaasssit, D'Argo.<br />
'''D'Argo:''' I caaaa' feel my tongue.<br />
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== Visual Novels ==
* ''[[
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** The real kicker? {{spoiler|Strong Bad referred to the substance in his younger brother's juice as Sanka. Strong Sad was somehow buzzing on ''decaffeinated coffee''. Which, admittedly, does have trace amounts of caffeine in it, and Strong Bad did say he added "several heaping spoonfuls" of the stuff.}}
** Additionally, Strong Bad and the Cheat both drink straight soy sauce with hilarious results in one episode. Strong Bad attempts to fly Bubs' Concession Stand to the moon, while the Cheat tries his best to eat it.
** In another email Strong Bad starts acting stranger than usual, and Strong Sad asks if he took "some of my pills again", suggesting that this sort of thing is [[Oh, No, Not Again|a regular occurrence]].
** In the sbemail "long pants", Homestar freaks out worse than usual upon being told that he looks like he isn't wearing any pants at all. In the later sbemail "email thunder", Homestar refers to that incident as the time he accidentally took some of Strong Sad's pills.
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* In [http://www.unshelved.com/2006-1-23 the sequence] from ''[[Unshelved]]'' where Dewey had mixed his muscle relaxants with his painkillers.
* In ''[[
* In [http://www.questionablecontent.net/view.php?comic=800 this strip] of ''[[Questionable Content]]'', a change in Hannelore's anti-anxiety medication (for her OCD) causes her to get all the way to the coffee shop without realizing that she was still in her underwear. [http://questionablecontent.net/view.php?comic=1279 This] strip lets us see what's making Tai so giggly while she's singing LSD's praises. "When you use big words, smoke comes out your nostrils!"
* In ''[[
** Much later Annie looked suspiciously like this after the [[Cuddle Bug|warm welcome]] of Foley kids in Chapter 36. It's not quite clear whether this happens because she let her emotions run free in a [[Heartwarming Moment]] or because she was {{spoiler|[[Astral Projection|out-of-body]]'ed in a crowd of ex-fairies}}.
* In ''[[Two Kinds]]'', [[Petting Zoo People|Keidrans]] can get insanely drunk off a couple slugs of normal beer. Then they start to talk like [[LOLcats]].
* In a Christmas arc in ''[[PvP]]'', Skull gets stoned on a bad orange julius and ends up taking a job as a [[Mall Santa]].
* [http://bukucomics.com/loserz/go/197 This strip] of ''[[Loserz]]''. And it was just ''coffee''.
* ''[[
* ''[[College Roomies
* The title character of ''[[
== Web Original ==
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== Western Animation ==
* Meatwad of ''[[
* In ''[[Daria]]'', Jake picks several unfamiliar berries while the family is out camping, which all but Daria eat. Soon, Jake and Helen are chasing after his spirit animal, while Quinn tries to use a mudpuddle as makeup; in the end, Daria has to call for them to be airlifted to a hospital.
{{quote| '''Quinn:''' But why did they go insane?<br />
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{{quote| [[Contemplating Your Hands|Clack... clack.]] And then minutes later: "Oh God, ''I'm coming down!!''"}}
** The essence of pure flavor is nothing more than water. Water laced with LSD.
* An episode of ''[[
* Happens in ''[[Beavis and Butthead]]''. Whenever the eponymous Beavis consumes too much sugar -- which doesn't actually seem to be that much -- he slips into his hyperactive alter-ego Cornholio. Part of the transformation involves pulling the back collar of his shirt over his head, holding both hands up, and commencing a quest to find "TP for my bung-hole!".
** In one episode the characters see an ad for non-alcoholic beer, which excites them when they find out you don't have to be 21 to buy it. After purchasing a pack, they sit on a sidewalk and try to become drunk ("We're fhit-saced!"). A cop comes by and gives them a test ("I'm too drunk to take a test!") which they naturally fail. The cop eventually sees that the beer isn't alcoholic, and tells them that they aren't drunk; they're just stupid. Disappointed that they aren't drunk, the two decide that all they need to do is drink more beer.
** There's also [[The Movie]], in which Beavis takes a bite of peyote in a desert and experiences [http://www.youtube.com/watch?v=A95qnv-oIuo a musical trip.]
{{quote| '''Beavis:''' Woah, this is cool! It's like... it's like everything looks all weird, and... ''woah!'' It's like there's all these weird shapes an'... it's sorta like... it's like a... [[Mythology Gag|it's like a music video!!]]}}
* Whenever Mac from ''[[
* In the ''[[Space Ghost Coast to Coast]]'' episode "Flipmode", Space Ghost gets high on gas fumes:
{{quote| '''Space Ghost''': Look: bean prints on the wrench. But what is the wrench for?<br />
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** In "D'oh-in in the Wind", he destroys the hippies' vegetable juice business by accidentally jamming the bottling machine with a <s>Frisbee</s> novelty flying disc. He makes up for it by picking all the other vegetables and putting them in the juicer, which turn out to be the hippies' "private vegetables;" we see a montage of townsfolk hallucinations and such, and Chief Wiggum tastes it and comments that "it's nothing but carrot juice and peyote."
** Bart goes on another sugar-induced bender with Lisa, when the family are on holiday in London. The shop-keeper warns them that English candy/chocolate "is sweeter than what they're used to" but the pair stuff their faces, and within seconds their pupils are dilated, and chaos ensues.
* ''[[Teen Titans (
* Sokka in ''[[Avatar: The Last Airbender]]'' winds up drinking some raw [[All Deserts Have Cacti|cactus juice in the middle of a desert]]. As a side note, many have heard of [[wikipedia:Peyote|Peyote]] but few realize that it is a cactus. Cue camera switching to Fish-Eye as Sokka becomes a [[Talkative Loon]]. He offers to share the wealth, insisting that cactus juice is the "Quenchiest!" His (much wiser) friends decline.
** "It's a ''giant mushroom''! Maybe it's friendly!!"
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'''Hogarth''': So she says, "Uh-uh, You don't have a challenge, you need a challenge." So now I'm challenged, all right, I'm challenged to hold on to my lunch money because of all the big mooses who wanna pound me, 'cause they think I'm a shrimpy dork who thinks he's smarter than them! But I don't think I'm smarter, I just do the stupid homework! If everyone else JUST DID THE STUPID HOMEWORK, they could move up a grade and get pounded, too! Is there any more coffee? }}
* In an episode of ''[[Ruby Gloom]]'', Misery overdoses on sugar. This being Misery, she starts running around the house, hyperactively reeling off disasters as they come to mind. ("Holland, 1134 -- SEA FLOOD! ''That's a lot of water...''")
* Happens in the ''[[
* [[Bugs Bunny]], typically [[Only Sane Man|one of the only sane characters]] in ''[[The Looney Tunes Show]]'', gets high on energy drinks in one episode and goes completely off the rails.
* Done a couple of times in ''[[Family Guy]]'' examples being when a young Peter was given LSD and told its a "cheesburger", he nearly kills himself from leaping off a tower believing he could fly had the Black Knight not saved him. Another episode, Peter and Lois smoke weed so they could get the inspiration for a talent show (which doesn't help them in the slightest as when they perform, from there POV, it was done beautiful. But in reality they were singing gibberish). Brian getting Stewie drunk to show him the effects of drinking with both getting hammered and crashing their car into the local bar. And Peter at one point trying cocaine, Brian tries to talk him out of it but typically Peter doesn't listen and when Brian comes to check on him later, Peter huddled on the couch shuddering and claiming "the gub'ment took my baby!".
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** Just in case you were thinking of going off and getting high on diet pills, the result of this is often death.
* [http://www.bbc.co.uk/news/world-us-canada-14770359 This happened to several people in an office] in Victoria, British Columbia, Canada in 2011, when one woman who worked there brought some brownies from home that she had found in her freezer. The folks who ate them thought that they had been poisoned; it turns out that the woman's son had baked pot brownies some time ago, tossed them in the freezer, and forgotten about them.
* This can happen to people when they drink on planes or just before getting on them. Travelers who turn out to be mean drunks often end up forcing the pilots to turn the plane back so the person causing the disturbance can be removed. In the [[The War
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