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* The envy and inadequacy suffered by Kirstie Alley's character Marjorie as a woman who has married into an entire family of doctors is the catalyst for the entire plot of ''[[Sibling Rivalry]]''.
* Speaking of the MD vs DO debate, the movie ''[[Alien Apocalypse]]'' has Bruce Campbell as a DO who saves the world from alien conquest using the power of osteopathy and pointed sticks. He continually complains about no one takes him seriously because he's a DO.
* [[Lampshade Hanging|Lampshaded]] in ''[[Star Trek IV: The Voyage Home|Star Trek IV the Voyage Home]]'': When Dr. McCoy starts to diagnose Chekov's condition, the other MD in the room [[Deadpan Snarker|snarks]]: "What's your degree in? [[Not That Kind of Doctor|Dentistry?]]" Of course [[
{{quote| ''"The doctor gave me a pill and I grew a new kidney!!"''}}
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