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== [[Live Action TV]] ==
* In ''[[Chuck]]'', the penultimate episode sees Chuck realizing that something is deeply wrong when a {{spoiler|mind-wiped Sarah gets snappish over a massage and then turns away from him in bed at night}}. He convinces himself that it's just the result of {{spoiler|her traumatic escape from Quinn}}, but he can't explain {{spoiler|what she's doing with the Intersect glasses in her bag}}.
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* In the second season of ''[[Angel]]'', Angel turns on his friends and finds himself without hope.
** Not to mention his role in the second season of ''Buffy'', after experiencing a moment of pure happiness (ie sex) with Buffy caused him to lose his soul.
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* ''[[Winx Club]]'': 4Kids turned Stella being a bit bitchy with her roomies from being part of her character to being the result of a spell, thus making it funnier. ([http://www.youtube.com/watch?v=EJa5UWOJDOg Clip]) There have been a few instances that are in both versions, though.
* Briefly in the ''[[Danny Phantom]]'' episode "The Ultimate Enemy" where Danny's [[Future Me Scares Me|evil self]], Dark Danny, goes to the past (present time) and disguises as his old fourteen-year-old self. His friends wonder what's up with him when he starts speaking rather eloquently, but being a [[Consummate Liar|smart bastard]], Dark Danny quickly fixes this and their suspects drop.
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** Danny also holds the dubious honor of at one point doing this ''twice'' at the same time. An accident splits his personality into the overly dramatic, comic style Hero Danny, and the laid back, mundane (and I quote) 'Fun Danny'. Confusion (and hilarity) briefly ensues.
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* Several illnesses or psychological factors can lead to a person's behavior changing dramatically. One of the most well known examples would be Phineas Gage, a railroad worker who was said to have been honest and reliable prior to an accident which lead to a metal pole being ''blasted through his head, damaging both his frontal lobes''. Afterwards, he became a much nastier person. The accident shed light on the effects that frontal lobe damage can have on personality.
** Maybe it wasn't the accident. In the words of the clearly well-researched website Cracked:
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** He wasn't competent to run his crew anymore. He didn't have ''respect'' anymore. Plenty to get mad about.
** He lost hypothalamus and frontal lobe connection, meaning less stuff was routed through the frontal lobes, particularly emotion.
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