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Mega Microbes (view source)

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== [[Film]] -- Live-Action ==
* [[Evolution (Filmfilm)|Evolution]] used a giant microbe. Technically, it's an amoeba...
* The B-Movie ''The Flesh Eaters'' features the titular micro-organisms joining together to become one large creature.
* ''[[Star Trek III: theThe Search For Spock]]'' has a set of microbes that get supersized thanks to the Genesis Effect. Later, they get so big that Captain Kruge gets to have a fight with one of them!
* In ''[[Fantastic Voyage]]'', the heros had to survive being caught in the crossfire of anti-bodies versus bacteria, "recticular fibers" that clog the intake ports, an direct attack on Grant and Cora by antibodies, and white corpuscles.
 
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== [[Live Action TV]] ==
* In an episode of [[Star Trek: theThe Original Series]], the Enterprise crew fight a space amoeba at least as big as a planet.
** There is another episode that involves [[Puppeteer Parasite|Puppeteer Parasites]] that are described as single cells that act as a [[Hive Mind]].
* An episode of ''[[Star Trek: Voyager]]'' has the crew dealing with [[You Fail Biology Forever|Giant Basketball-sized flying viruses]].
** On the subject of Star Trek, [[Star Trek: theThe Original Series|the original series]] had its own truly humongous, space-borne and of course ''Enterprise''-threatening example in "The Immunity Syndrome".
* Used in [[Fringe]], with a single-celled cold virus grown to the size of a cucumber. Yes, they did call it a "[[Taxonomic Term Confusion|single-celled virus]]".
 
== Tabletop Games ==
* There's a [[Yu-Gi-Oh Card Game]] card called [http://yugioh.wikia.com/wiki/Giant_Germ Giant Germ] that deals damage and acts like an [[Asteroids Monster]].
* Phyrexian Living Weapons in [[Magic: theThe Gathering]] come into play automatically attached to a 0/0 Germ token. The germ can't survive on its own outside of the weapon, but with a few buffs to its toughness and power it's possible to beat things up with a giant Germ.
 
== Toys ==
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== [[Video Games]] ==
* The third boss of ''[[El Viento (Video Game)|El Viento]]'' is a huge single-celled organism.
* Morpha from ''[[The Legend of Zelda: Ocarina of Time]]'', whose [[Boss Subtitles]] identify it as a Giant Aquatic Amoeba.
* ''[[City of Heroes]]'' has Hamidon, giant single-celled organism and endgame raid boss.
* In ''[[Xenoblade Chronicles]]'', these show up as enemies in the Bionis' Interior, and all possess the trait of being highly resistant to physical attacks.
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== [[Web Original]] ==
* [http://scp-wiki.wikidot.com/the-bacterium-part-one This story] at the [[SCP Foundation (Wiki)|SCP Foundation]] site.
** And now [http://scp-wiki.wikidot.com/scp-371 SCP-371].
 
== [[Western Animation]] ==
* ''[[Johnny Bravo]]'' episode "The Incredible Shrinking Johnny" ends with an amoeba accidentally enlarged to giant size, which proceeds to chase Johnny and Carl down the street.
* ''[[Superman: The Animated Series (Animation)|Superman the Animated Series]]'' featured a brief appearance by ameoba enlarged to human size in the episode that introduced the giant ape "Titano".
* The Amoeba Boys are a gang of three dimwitted crooks in ''[[The Powerpuff Girls (Animation)|The Powerpuff Girls]]''. They're about the size of humans, and sort of float along the ground.
* ''[[Swat Kats (Animation)|Swat Kats]]'' had a legion of [[Blob Monster|gigantic purple bacteria monsters]] in its second episode, "The Giant Bacteria". The trouble is, they didn't much look like germs, possessing eyes, mouths and a definite torso shape with arms and legs, due to the first one having originally been an ordinary guy ([[Extra Eyes|more or less]]) who gets mutated by [[Mad Scientist]] [[Complete Monster|Dr. Viper]].
 
== Real Life ==
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