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{{trope}}
[[File:
{{quote|''"Does he really have to kill them to prove his point? Can't he just show them a pie chart?"''|'''Joel Robinson''', ''[[
Mad science isn't just about cool gadgets or revenge; it's a ''[[Chronic Villainy|compulsion]]''. The [[Mad Scientist]] really ''is'' insane, with an actual psychological disorder that causes both brilliance and madness.
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Although obviously more extreme than in real life, this sort of thing is [[Truth in Television]] (or other media): Some medications used to treat mental illness leave the patient drained of energy, unable to think clearly, cut off from the full use of the senses, or any combination thereof. This is one factor in some of the many [[Mad Artist|historical geniuses]] and others who refuse to take their medication, preferring insanity to a lackluster funk.
Named for the communicable form of mad science in the [[Web Comic]] ''[[
Compare [[With Great Power Comes Great Insanity]], which, depending on the series, may be either the cause or the result of SRMD. Likely to lead to a [[No Medication for Me]] / [[Flowers for Algernon Syndrome]] situation. Can quickly lead to [[The Madness Place]]. Not to be confused with [[Memetic Mutation]]. Also compare [[The Spark of Genius]], which is sometimes combined with this syndrome.
=== Known Vectors: ===▼
== [[Anime]] and [[Manga]] ==
* In ''[[
** Well, in Stein's case, you could say he was crazy and THEN took to science as he grew up. Young Stein is pure [[Slasher Smile]] [[Nightmare Fuel]], with a side of "Take it apart to see how it works." With 'it' often being a living, breathing thing.
*** He got pretty good at putting 'it' back together too.
* The Whispered in ''[[Full Metal Panic
* Doctor Jail Scaglietti, the [[Big Bad]] of ''[[Magical Girl Lyrical Nanoha
== [[Comic Books]] ==▼
▲== Comic Books ==
* Will Magnus, the creator of the [[Metal Men]] in the DC universe, suffers from bipolar disorder. Taking pills prevents him from acting irrational and creating machines of death - like making a robot out of uranium - but also stifles his creativity - like making a sexy robot out of platinum.
* In some of his incarnations, the Lizard form of Curt Connors in ''[[Spider-Man (Comic Book)|Spider-Man]]'' acts like a mad scientist, even though normally, he is a good guy. Complicating things is that on other occasions, the Lizard form is non-sentient.
* Most versions of ''[[The Incredible Hulk]]'' revolve around Bruce Banner's attempts to resolve his... shall we say, emotional issues?
* Hank "Ant-Man" Pym. As he has stated, he only takes on board scientific projects that interest him or stimulate his imagination. He is also somewhat prone to [[Freak
** One theory is that he's neurotically obsessed with ''being a super-hero'', despite being completely insane.
* Mento of [[Doom Patrol]] is arrogant and mentally unstable at the best of times. He's also a freaking genius with several doctorates and a business savant who makes Batman look broke. He started heroing both to impress his (then-future) wife and because he was ''bored.'' It was after he lost Rita that he really went downhill.
* Everett Ducklair from ''[[PKNA]]'' couldn't help himself with this trope, as near-everything he created turned out to be a weapon of mass destruction.
== [[Fan
* In the ''[[Narbonic]]''/''[[
== [[Film]] ==
* One character in ''Transylvania 6-5000'' is a normal scientist as long as he's outside his laboratory. On entering it, however, he proceeds to muss up his hair and go into full-blown [[Mad Scientist]] mode.
* It's implied that the title character of ''[[Young Frankenstein]]'' inherited his tendency toward mad science from his more famous predecessor.
** In the musical, it's stated outright. In fact, it's sung, in "Join The Family Business":
{{quote|
The Rothschilds are famous for their wines
Hersheys have their chocolates, and Liptons have their teas,
But when it comes to making monsters you can't beat the Frankensteins! }}
==
* Oliver Sacks' book ''The Man Who Mistook His Wife For A Hat'' mentions a jazz drummer who has Tourette's Syndrome. He would take his anti-Tourette meds during the week, and be less prone to compulsions; but stop taking them for the weekend so he could do the wild drum improvisations that made him a desirable musician.
* Supervillains often suffer from "Malign Hypercognition Disorder" in Austin Grossman's book ''[[Soon I Will Be Invincible]]''. It's stated that the [[Mad Scientist]] types will go this way when they are at the far right edge of the bell curve. Doctor Impossible knows his plans will be thwarted, knows he could use his inventions for other purposes, but has a psychological compulsion to try and rule the world. His alternating attempts to hide the painful truth from himself and justified self pity make him [[The Woobie]].
** Another [[Retired Monster|former villain]] with the same condition, Baron Ether, seems to have come to terms with the fact that he has an incurable condition and is burned out on the constant cycle of escape and doomed plans of world conquest: he needs to be kept under house arrest, and would of course escape in a heartbeat given the chance, but he really doesn't want to. He tries to get Dr. Impossible to understand, but it [[Cassandra Truth|bounces right off his dementia.]]
* In one of [[Larry Niven]]'s ''[[Known Space]]'' short stories, appropriately titled "Madness Has its Place," it's revealed that ARM (the technology-suppressing [[Secret Police]] branch of the UN) deliberately employs sociopaths and paranoid schizophrenics, though they're issued mandatory medication. The main character is one (he's implied to be a former serial killer), but in order to help prepare a defense against the approaching Kzinti aliens, he goes off his medication. His descent into paranoia and sociopathy make him frighteningly competent at war preparations for a humanity that hasn't known war in centuries. The ARM also creates treatments to ''artificially'' induce paranoid schizophrenia and other disorders in its agents, in case enough naturally occurring crazies of the right sort are unavailable.
* Although they're rarely developed characters, any Marthter that any Igor has worked for on the ''[[Discworld]]''. Either they start out mad, or become mad, as a result of their scientific activities. ''[[Thief of Time]]'' has an example of a developed character of this sort.
* In the [[David Brin]] novel ''Kiln People'', Mad Science is caused by one of several psychological complexes. The protagonist, a private detective with an interest in psychology, listens to the villain ramble and mentally goes down a list of symptoms, eventually diagnosing him with a textbook case of one of the complexes.
* Played straight in the ''[[Morganville Vampires]]'' books, Myrnin is a [[Mad Scientist]] vampire who has developed a disease that only targets vampires, he tries to find a cure and managed to develop medication to slow it down, but often forgets to take it, turning him into a bloodthirsty monster, which is why he needs someone there to help him remember, but hiring an assistant often doesn't go well.
*
== [[Live
* One episode of ''[[
* The title character of ''[[House (TV series)|House]]'' seems to need his physical pain and emotional bitterness in order to keep his remarkable (if unorthodox) medical talent. When he tries methadone he finds himself pain-free, cleans himself up, and seems genuinely happy... until he realizes he's lost his edge.
** Actually, it was that being pain-free made him act uncharacteristically nice and accommodating to the worried parents of his patient which directly resulted in creating a health problem when the kid had actually just been dehydrated (he had a reaction to the contrast dye in their first test, everything else stemmed from that). That House believes he would have caught this right away otherwise was probably at least partly a rationalization on his part; The truth is being pain-free made him nicer, not dumber, and he's really just scared to find out how much of his personality and worldview was a result of his constant pain (the guy is terrified of change).
== [[Tabletop Games]] ==
* In the tabletop RPG setting ''[[Deadlands]]'', "[[Mad Scientist]]" is actually a type of playable character. While it isn't a disease in the classic sense, being a [[Mad Scientist]] in this setting is an incurable condition, as {{spoiler|demons whisper clues about devices that should not work, but do, into the ears of eager listeners, all in an attempt to hasten [[The End of the World
* Although all [[Our Orcs Are Different|Orks]] in ''[[Warhammer
* ''[[
** In ''[[
** In ''[[
* In ''[[
* ''[[
* ''[[Dungeons
==
* Cave Johnson, the founding mind behind Aperture Science, in ''[[Portal (
** In [[
* ''[[
* The genetic condition of Mad Science (aka hypercognitive dementia, also known as Walton's Disorder, also known popularly as Mad Genius; DSM-IV numeric code 29533) and its eventual treatment is also the major theme in ''[[
** Because of their apparently shared [[The Verse|'verse]], Mad Scientists show up in [[Skin Horse]] as well. [[Sassy Black Woman|Tigerlily]] and Captain Bram so far, but there's a whole "Institute for the [[Blatant Lies|Sane]] Study of Mad Genius" out there.
* ''[[
** Baron Klaus Wulfenbach is notable because he is the only Spark seen that is mostly ''immune'' to this, though he still has his moments. As Tarvek says to Gil {{spoiler|when he realizes that the Baron has been slaver-wasped but is somehow [[Fighting From the Inside]]}}, Klaus Wulfenbach is special and breaks all of the "rules" concerning Sparks.
* The "inventor's gene" in ''[[General Protection Fault]]'' is a relatively benign form of this.
* Hannelore's father in ''[[
▲== Web Original ==
== [[Web Original]] ==
* In the ''[[Whateley Universe]]'' webfiction, there exists a disorder by the name of Diedrick's Syndrome, in which an imbalance of neurotransmitters can, to paraphrase another troper, lead to the sufferer screaming insanely about destroying the planet because, say, he originally just lost his car keys. (Such an episode is referred to as "dricking out".) A devisor named Mega-Death is the current trope demonstrator. Ironically, he's a REALLY nice, friendly guy. Normally. It's been suggested that the Alphas are screwing with his inventions to induce more frequent 'drick-outs [[For the Evulz|because they think it's funny]].
** Devisors also frequently forget to do things like eat or
* In the web novel ''Star Harbor Nights'', people who have the Darkwell gene are somewhat mad-scientisty, moreso if they've inherited it from both their parents. The most normal of the double Darkwells we've met so far carries a stuffed rabbit with her everywhere and talks to it, and has a... very well-equipped lab in her basement:
{{quote|
* [[The Spoony Experiment
* One episode of ''[[American Dad (Animation)|American Dad]]'' had the son's mentally disabled best friend go off his meds. He went from being a sweet mentally disabled child to being a [[Evil Brit]] Mad Genius. It turns out those pills have been keeping his [[Super-Powered Evil Side]] in check for years.▼
== Video Games ==▼
▲* Cave Johnson, the founding mind behind Aperture Science, in ''[[Portal (Video Game)|Portal]]''. It's [[All There in the Manual]] that he inadvertently came up with an idea for a quantum hole in the space-time continuum, which he thought could have applications as a shower curtain.
▲** In [[Portal 2 (Video Game)|Portal 2]] it's revealed that the central programming for testing produces a data burst akin to pleasure for the main AI when a test is completed, but the AI rapidly develop an immunity to it. This becomes a plot point when {{spoiler|Wheatley takes over and begins to suffer "test withdrawal"}}.
==
▲* One episode of ''[[
* [[Nikola Tesla]] may have had a bit of this.
* John Nash, the schizophrenic mathematician portrayed in ''[[A Beautiful Mind]]'', found that his medications drained his energy and left him unable to accomplish anything, so he stopped taking them, electing instead to battle his mental illness with cold, methodical logic.
* A lot of sufferers of bipolar disorder (formerly known as manic depression) or other mental disorders complain that the medication keeping them stable stifles their creativity.
** Subcritical manic state (hypomania) has shown distinct connection with heightened
* Studies have shown that there's a slight trend for people with creative jobs to have a mental disorder. (For the science people: It's actually really slight, but supposedly outside their margin of error.) This isn't "everyone who does something well is insane," more like "if you do something well, you're statistically slightly more insane than everyone else."
** People who are better at thinking outside the box than others may not realize when thinking ''inside'' the box is more appropriate, leading to perceived eccentricities.
* Paul Erdős, a mathematician known for publishing more papers than any other mathematician to date and collaborating with damn near everyone in the field, took amphetamines. He was offered a sum of money by a friend to give up the habit for a month. He did, took the money, then went right back on amphetamines, claiming his sobriety impeded his ability to think.
{{quote|
{{reflist}}
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[[Category:Tropes On Science and Unscience]]
[[Category:Intelligence Tropes]]
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