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* [[Yotsuba&! (Manga)|Yotsuba&!]] has Yanda, whom she instantly hates with a hatey five-year-old hate but other characters merely find annoying. It doesn't help that Yanda takes a [[Adult Child|childish glee]] in figuratively yanking her pigtails.
* Piyoko from ''[[Di Gi Charat (Anime)|Di Gi Charat]]'' and the Digi Devil from ''Panyo Panyo Di Gi Charat'' really ''try'' to be legitimate [[Big Bad|Big Bads]], but being inept villains in humor series whose schemes rarely rise above the level of [[Poke the Poodle]] dooms them to be this instead.
* Watanuki from ''[[Xxx HO Li C (Anime)|Xxx HO Li C]]'' hates Doumeki for no adequately explained reason, and just refers to him as annoying him since the moment they met. Unfortunately for Watanuki, Doumeki is also a living spirit repellent, while Watanuki's very blood attracts spirit, so he's often forced into [[Teeth
* In ''[[Kekkaishi (Manga)|Kekkaishi]]'', Shigemori and Tokiko spent their mornings attacking each other with gardens hoses; it's part of their feud about the 'legitimate heir' of the Kekkaishi founder. Both are rather upset that their grandchildren don't share their grudge.
* ''[[Boku wa Tomodachi ga Sukunai (Anime)|Boku wa Tomodachi ga Sukunai]]''
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* In ''[[Frasier]]'', Frasier had Cam Winston. The two were virtually ''identical'' to each other, in that they were pompous, snooty, articulate egomaniacs. When they finally called a truce because they thought their parents were dating, their "treaty" included them agreeing to share grooming and personal care advice on features the other one had noticed.
* In ''[[News Radio]]'', Jimmy James had Johnny Johnson.
* In ''[[
* In ''[[Wizards of Waverly Place]]'', the [[Magnificent Bastard]] [[Anti-Hero|Alex Russo]] has [[Alpha Bitch|Gigi]].
* In ''[[Cheers]]'', Sam's nemesis was the rival bar "Gary's Old Town Tavern".
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== Web Comics ==
* ''[[
** Later on Cole admits that he doesn't even really have a good reason for hating Max, he's just petty and begrudges Max the fact that he's an overall good guy ''and'' more successful than Cole<ref>the only hint of anything less than exemplary character on Max's part, in fact, was an inability to see Skull the troll, and this is hinted to be more self-absorbtion than any legitimate sin on Max's part</ref>. This admission prompts Max to [[Put On a Bus|go on walkabout, as the Australians call it]], and he eventually comes back with the grating edges sanded off his personality, and the staff of the magazine grow to think of him as a good friend<ref>He can see Skull too</ref>.
* In ''[[Sluggy Freelance (Webcomic)|Sluggy Freelance]]'' Gwynn seems to feel she and Torg have this relationship at times. Torg actually thinks of her as a really good friend, if maybe a little too hot-headed.
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** Ron Stoppable and Mr. Barkin
* ''[[Angela Anaconda (Animation)|Angela Anaconda]]'': "Oh no, it's [[Alpha Bitch|Ninny-Poo]]."
* Bessie Higgenbottom of ''[[The Mighty B]]'' has three of these. The first being [[Alpha Bitch]] Portsia. The second being Portsia's [[Yes
* ''[[My Gym Partner's a Monkey (Animation)|My Gym Partners a Monkey]]'' [[The Protagonist|Protagonist]] Adam Lyon has Principal Pixiefrog, Bull Sharkoski and Chad.
* Trudy Beekman from [[Archer]] who's [[The Ghost|never actually been seenl]] on the show, but Mallory almost constantly complains about her.
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[[Category:Characters As Device]]
[[Category:Sitcom Arch Nemesis]]
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