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* In [[Neil Gaiman]]'s novel ''[[Neverwhere]]'', Villains Croup and Vandemar use the lower levels of an abandoned hospital as their hideout.
* In ''[[The Stand]]'' by [[Stephen King]], The Stovington Plague Center in Vermont turns into this [[After the End]].
** ''[[The Dark Tower (Literature)/Wolves of the Calla|Wolves of the Calla]]'' by the same writer features a hospital where {{spoiler|doctors extract something from twin children that feed the psychic abilities of others. The children end up as overgrown idiots}}. It also turns into the abandoned version of this a little later in ''[[The Dark Tower]]'' story.
* ''The Blackstone Chronicles'', a series of short horror stories by John Saul, revolve around an abandoned insane asylum whose patients and former staff end up connected to a series of murders. It was later made into a computer game.
* ''[[Hannibal]]''. FBI agent Clarice Starling returns to the mental institution, now closed down, where Hannibal Lecter was imprisoned to dig up some old files. Most chilling of all is the fact that one of the inmates (who'd cut off his mother's head) is now living there as a homeless outpatient, though nothing happens between them.
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