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** In ''The Last Continent'', the cowardly and cynical Rincewind turns into a boisterous optimist after a few Ecksian beers.
** ''Carpe Jugulum'' has timid [[Non-Action Guy|Non Action King]] Verence transforming into [[The Berserker]] after having a single sample of the Nac Mac Feegles' "brose," which is [[Gargle Blaster|specifically designed to do just that]]. These are the fairies that consider Nanny Ogg's "sui-cider" a delicacy, after all. It's also lampshaded that giving him fifty times the brose, just because he's bigger, probably wasn't the best idea.
** Subverted with Lord Vetinari. In ''[[Discworld/Unseen Academicals|Unseen Academicals]]'' he gets stone drunk. It's mentioned that men twice his size with a reputation for being able to hold their drink had been hauled home in wheelbarrows, but despite having drank just as much as they had the only noticeable difference in Vetinari's behavior is that he's a bit more talkative than usual, and it's a bit harder the next day for him to do the crosswords in the morning paper. Apparently, he's very good at acting sober. Or very, very Knurd. However, that's not really his only reaction. In one part of that scene, he seems a lot more sad and philosophical than usual, giving a short, depressing monologue on the ubiquity of evil and staring into his drink. He acts quite normally otherwise, though.
*** Played straight in that same book, where the normally strait-laced Glenda finally starts to loosen up after a few glasses of sherry.
* A major plot point in ''[[The Three Musketeers (novel)|The Three Musketeers]]'' hinges on a devastating autobiographical story Athos tells while drunk.
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* The basic concept behind most real life [[Truth Serum]]s is that they render a person more likely to talk in general and less able to come up with a convincing lie. Incidentally, the only two substances that have been proven to be fairly consistently effective as (relative) [[Truth Serum]]s are alcohol and marijuana. The former was a favorite of the KGB, whose agents were [[Vodka Drunkenski|able to keep cover while their Western opposite numbers started gushing]]. The latter was tried out by the FBI, in the form of THC-laced cigarettes, on a member of [[The Mafia]], who spilled the beans on a heist, embarrassing the [[CIA]]'s [[Government Conspiracy|MKULTRA]] (which was trying to do the same thing with more exotic substances like acid) in the process.
* Kamikaze pilots were given a shot of sake as part of an honor ceremony before they left on their suicide mission. It is most likely that this drink was included in the ceremony to dull their nerves and heighten their courage to go through with the mission.
* In normally strictly hierarchalhierarchical Japanese corporate culture, the ''nomikai'' after -work drinking party is one of the few occasions workers can give free rein to their true thoughts, and anything uttered in the course of such that would face censure at any other time is usually excused as the result of a drink-loosened tongue.
 
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