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* ''[[Dead Rising]]''. Carlito dies if you continue the main storyline, but he has already destroyed one American city and has planted walking [[Zombie Infectee|children zombie bombs]] with host families all over the country.
* The third ending of ''[[Drakengard]]''. Manah gets the closest to succeeding in her plan—only to get defeated by the dragons, who suddenly decide that enough is enough and that [[Kill All Humans|humanity has to die]] before they end up dooming the world.
* So far in ''[[Adventure Quest Worlds]]'', the hero always arrives too late to stop the Chaos Lords from summoning their respective [[Sealed Evil in a Can|Chaos Beasts]] (in one case, he/shethey actually gave the item sought by the first lord of chaos, Escherion, to him so he could use it to free the Lake Hydra, and in another, Discordia was actually a fake Chaos Lord so he didn't have his own Chaos Beast - the real Chaos Lord, Kimberly, on the other hand, used her power of rock to send him/herthem back in time where her Pony Gary Yellow was enlarged and brought to life). He/sheThey defeatsdefeat the Chaos Beasts anyway, though.
* In ''[[The Legend of Zelda: Ocarina of Time|The Legend of Zelda Ocarina of Time]]'', Link's first serious task is to free the [[Wise Tree|Great Deku Tree]] from a potentially fatal curse. While Link kills the boss that was the source of the curse, the Deku Tree was doomed before Link even started. The Deku Tree knew this all along, he justand decided to make the best of a bad situation by getting Link started on his quest. It's later revealed that the Deku Tree reincarnated seven years later.
* In ''[[Hitman|Hitman: Contracts]]'', one of the targets in the second mission is Campbell Sturrock, aka the Meat King, - [[Fat Bastard|a morbidly obese Scottish crime boss]] who's so fat he needs a wheelchair simply to move. Clearly a monster, heHe was prosecuted for kidnapping a wealthy man's daughter (your client), only for his sleazy lawyer (your other target) to get him off on a technicality. The client asks you to rescue her, if possible.; Sadlysadly, you cannot, as the girl is dead by the time you get there, horribly dismembered and mutilated by Sturrock's sociopathic brother, Malcolm. You can kill Malcolm if you want, as he obviously deserves it, but doing so is not required to complete the mission.
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