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{{trope}}
[[File:desugriniq0.jpg|link=Rozen Maiden|
[[wikipedia:Heterochromia|Complete heterochromia iridis]] is a medical condition where an individual has different-colored eyes.
In fiction, this often indicates a character with special powers, perhaps a [[Shape Shifter]] or magical being of some sort: traditionally, people with different colored eyes were literally assumed to be a witch, or a (possibly evil) spirit. If so, they [[Glamour Failure|can't mask]] their distinctive eye in any form. Unlike [[Red Eyes, Take Warning|red eyes]], this may be merely a sign of a [[Trickster]], or someone with hidden attributes.
Alternately, it may indicate a [[Half-Human Hybrid|dual nature or origin]]. Given the prevalence of [[You Gotta Have Blue Hair|odd hair colors]] and albinism in animation, just being pale with red eyes isn't symbolic enough anymore. Sometimes this is the budget version of [[Half-Human Hybrid|Half Human Hybrids]], but in any case it's some easily remembered [[Fashionable Asymmetry]] that doesn't aggravate the artists much (unless they have trouble remembering which eye is which color).
In real life, there are exceptionally rare instances where each eye might have multiple colors, but this usually doesn't show up in fiction.
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As said above, it exists in real life, but in fiction, it will often use an impossible color for at least one eye.
A subtrope of [[Technicolor Eyes]], related to [[Good Eyes, Evil Eyes]]. If a villain has these, it's a [[Red Right Hand]]. If one of the [[Eyes of Gold|eyes is Gold]], your ass is grass.
Sometimes referred to as "boat lights", a reference to the red and green lights that mark port and starboard on boats and aircraft. Note that for proper boat lights the red eye would be the left eye. Souseiseki's eyes
Note the [[Real Life]] diseases of which [[heterochromia]] is often a symptom do not appear much in fiction. This trope is not to be confused with [[Fish Eyes]].
{{examples}}
== [[Anime]] and [[Manga]] ==
* In ''[[11eyes]]'', Kakeru has a [[Eyes of Gold|blind right eye]], covered by an [[Eyepatch of Power|an overly large eyepatch]] and a completely normal blue left eye.
* Jio Freed from ''[[666 Satan]]'' has one blue and one red eye, as well as half-and-half hair. This is mainly to symbolize the fact that he [[Super-Powered Evil Side|is a host to Demon 1i, Satan]].
* Tokidoki from ''[[Amatsuki]]'' has one brown eye and one red eye; the red one indicates that his vision was stolen from it by a nue.
* Arios, the [[White
* Kanade from ''[[Asura Cryin]]'' normally has blue eyes, but when she uses her powers, one of them turns to green.
* Nei in ''[[Avenger]]'' has heterochromia to indicate that {{spoiler|she (or he, it ain't exactly clear, either) is both a [[Robot Girl]] and a real human. Well, actually, she/he is neither but has the potential to become one of the two.}}
* Sven from ''[[Black Cat (
** His mismatched eyes are also [[Justified Trope|justified]] in a
* In ''[[Black Lagoon]]'', Balalaika is occasionally shown with her right eye glowing yellow-ish.
* [[Cloudcuckoolander|Nenene]] and [[Handsome Lech|Toki]] from ''[[Code Breaker]]'' both have one blue and one brown eye. This almost gets Nenene killed when fire <s>
* {{spoiler|Jeremiah Gottwald}} in ''[[Code Geass]]'' ends up as this after he is made into a cyborg, with one orange eye and the replacement one being green. Arguably, Geass users as well, as when the [[Power Incontinence]] hits, it's usually only in one eye at first, meaning one eye will be its normal color, and the other will have the Geass symbol permanently imprinted on the iris.
* Almost-example: Spike's eyes on ''[[Cowboy Bebop]]'' are slightly different shades of brown. It's very hard, but possible, to notice this before he brings it up to Faye. The reason is that one is a [[Artificial Limbs|cybernetic replacement]] for an eye he lost in a very symbolic and personal tragedy.
** Spike's
** This feature was brought up rather explicitly in the climax of episode 20, "Pierrot le Fou", where it is revealed that {{spoiler|the cat that was present during the title character's horrific experiments (and was responsible for his [[Why Did It Have to Be Snakes?|ailurophobia]]), had heterochromia, leading to him freezing up at a crucial moment during the final showdown with Spike due to the light making his cyber-eye glow in a similar fashion to the cat's, allowing Spike to defeat him}}.
* Allen Walker from ''[[D
* A minor [[Differently
* Luki and Noki from ''[[DOGS Bullets and Carnage]]'' have very weird eyes (gold with a black iris, black with a gold iris, with the actual which-eye-is-which swapped between twins). They're [[Enfant Terrible|enfants terribles]].
* The Count from ''[[Gankutsuou]]''. This symbolizes not only his moral ambiguity and inner conflicts, but also the fact that he is {{spoiler|[[Ninja Pirate Zombie Robot|part-human, part-monster, part-alive, part-undead and part-earthling, part-alien]] through his symbiosis with Gankutsuou}}. The duality symbolism is also present in some representations of his crest, a stylized heart divided into two clear compartments with different colours to represent {{spoiler|his remaining human feelings and the fact that he is gradually turning into a cold-hearted monster}}.
* Vetti Svorza of ''[[Glass Fleet]]'' has one purple eye and one [[Eyes of Gold|shiny gold one]]. It's one of the early indicators that he's [[Royally Screwed
* Urumi Kanzaki from ''[[Great Teacher Onizuka]]'' is heterochromatic and {{spoiler|was conceived via artificial insemination}}.
* Allelujah Haptism from ''[[Mobile Suit Gundam 00]]'' has a [[Gray Eyes]] and a [[Eyes of Gold|gold]] one. His hair always obscures one of the two, cluing any viewers into whether it is he or his evil [[Split Personality]] Hallelujah that is currently in control. {{spoiler|In the end, he ends up pulling his hair back to reveal both eyes, allowing both [[Split Personality Merge|personalities to simultaneously control his body, giving him the reflexes of two people]].}}
* Albireo from ''[[.hack
* The [[Artificial Human]] [[Onmyodo|onmyouji]] Abe no Yasuaki and his [[Expy]] Abe no Yasutsugu from the ''[[Harukanaru Toki no Naka
** The fifth game in the series seems to be continuing the tradition with Amami (blue and purple). (It's a lot more obvious on Tohko Mizuno's illustration than on the CG image.)
* Posaydal from ''[[Heavy Metal L
* ''[[Kamichama Karin]]'' has Michiru, a brunette with one purple eye (his natural color) and one blue eye ({{spoiler|which was implanted by Professor Kujyou after his eye was [[Eye Scream|crushed beyond repair]] in a car accident when he was a kid}}).
* In ''[[Katekyo Hitman Reborn]]'' Rokudo Mukuro has a red right eye with kanji in it and a normal, blue left eye. His right eye changes the kanji to suit the number of which path's (six paths of hell) powers he is using at that moment.
* Heterochromia becomes an important clue in one of the extremely difficult mysteries ''[[The Kindaichi Case Files|Kindaichi]]'' is forced to unravel.
* Ciel Phantomhive from ''[[
** Alois later gets these when he {{spoiler|makes a contract with Hannah, Claude, and Sebastian.}}
* Mika Ayanokoji from ''[[Kyoshiro to Towa no Sora]]'', whose right iris is purple and the left, orange (though, the latter may be an implant). Her dual nature seems to be that she is simultaneously [[Manipulative Bastard|manipulative and scheming]] and [[Psycho Lesbian|dangerously passionate for Kaon]].
* Oskar von Reuentahl from ''[[Legend of Galactic Heroes]]'' has one blue and one brown eye, which is the bane of his life -- {{spoiler|it reminded his mother of her illicit affair and drove her to suicide, which caused his father to hate him with a passion.}}
* Rosario from ''[[Lupin III]]: The Columbus Files'' has different colored eyes for plot-relevant reasons. {{spoiler|her left eye was discolored by the laboratory explosion that killed her mother and the peculiar red-brown color allows her estranged [[Mad Scientist]] father to identify her as his child.}}
* Vivio, from ''[[Magical Girl Lyrical Nanoha StrikerS]]
** In ''[[Magical Girl Lyrical Nanoha
* Asuna from ''[[Mahou Sensei Negima]]'' has heterochromia. The exact significance is unknown, but it's especially notable for its ''absence'' in adaptations that don't get into her [[Backstory]].
** {{spoiler|Volume 26's cover has revealed that Arika Entheofushia -- Asuna's relative and Negi's mother -- has/had this as well}}.
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* ''[[Naruto]]''
** If we're counting implants, then it would be appropriate to mention Kakashi Hatake's singular Sharingan eye, which he keeps hidden under his askew headband. {{spoiler|Ditto for Danzo. One of the other Kage's bodyguards has a Buyakugan in same setup.}}
** Zetsu from , although has two yellow irises, has different color sclera (the whites of the eyes) to go with his [[
** {{spoiler|As of chapter 514, [[Big Bad|Tobi]] has been confirmed to have implanted a Rinnegan in his left eye, while his right remains a Sharingan.}}
* The eponymous [[Hell Hound]] of ''[[Nora]]''; when in human guise, his right eye is red and his left is yellow.
* Vincent from ''[[Pandora Hearts]]'', who has [[Red Eyes, Take Warning|one red eye]] and [[Eyes of Gold|one gold/yellow eye.]]
* The Count D from ''[[Pet Shop of Horrors]]'' has heterochromia, one eye being purple and the other, whom he hides under his hair, is golden. In the manga, it's explained that {{spoiler|this is meant to be representative not only for his non-human nature, but also for his inheritance: his father and grandfather have golden and purple eyes, respectively. Since each one has a very different personality, and D has personality traits from ''both'', his heterochromia symbolizes this dual nature}}.
* Ramses from ''[[Red River]]'' has one brown eye and one golden eye.
* In ''[[Rosario
* In ''[[Rozen Maiden]]'' Suiseiseki has red and green eyes, and was originally nicknamed "Boatlights-chan" by fans before she became known as simply "[[Verbal Tic|Desu]]". Her twin sister Souseiseki, introduced later, has the same eye colors but reversed. Appropriately, they are [[
* ''[[Saint Beast]]'': Goh{{context}}
* One of the characters of ''[[Saki (
* [[Big Bad]] God of War Homura from ''[[Saiyuki]]'' has one [[Eyes of Gold|golden]] eye, and one blue one, as a result of his [[Half
** As does Hakkai when removing his power limiters.
* The perpetually-bandaged Abiru Kobushi from ''[[Sayonara, Zetsubou
* Mikuni from ''[[Shangri-La]]'' has one [[Eyes of Gold|gold eye]], and one blue eye.
* [[Pettanko|Mayumi Thyme]] from ''[[
** They were blue and '''red''' in VN.
* The clone Rezo the Red Priest, [[Big Bad]] of Season 1 of ''[[Slayers]]'' has one blue eye and one yellow. Since he is blind, he [[Eyes Always Shut|has his eyes closed]] throughout most of the season. His magic clone thingy gets mismatched eyes after bonding with a vaguely defined 'demon-beast' that doesn't seem to actually fit into the hierarchy of evil in the world's mythology.
** Copy Rezo was shown with mismatched eyes from the start, although when he first shows up, {{spoiler|he's keeping them closed on purpose, even though he can see, because he's posing as the original Rezo}}. In the original light novels that the anime was based on, Copy Rezo kept his eyes closed for a [[Body Horror|different reason altogether]].
* In ''[[
* In the second novel of ''[[Suzumiya Haruhi]]'', Haruhi gives Mikuru one colored contact to wear during their filmed home movie, because "different colored eyes give an air of mystery". Hey, if anyone [[Genre Savvy|knows her tropes]], it's Haruhi.
** Though anyone watching the first broadcast episode ''alone'' won't know why it was there ''for one shot only''. Other than <s>continuity issues</s> [[A Wizard Did It|Haruhi did it]], it's a case of [[All There in the Manual|All There
* Syaoran of ''[[Tsubasa Reservoir Chronicle]]'' has differently shaded eyes to signify how one is blind. This ''further'' symbolizes how {{spoiler|he only has half a soul, donated to him by the real Syaoran, of whom he is a clone. When the real Syaoran awakens, the Syaoran we've been seeing not only turns evil, but rips out Fai's eye (containing his magic) and eats it, turning his blind eye blue.}}
** By the last chapter of the manga, it's possible (although not confirmed by a color image) that
* [[Big Bad]] (of at least one arc) Rido Kuran of ''[[Vampire Knight]]'' has one blue eye and one crimson eye, a trait that shows up in the people he possesses. This is the first clue to Rima Touya that something's [[Not Himself|not quite right]] about Shiki...
* [[Tyke Bomb]] siblings Segiri and Suika in ''[[Weiss Kreuz]]: Gluhen'' each have one blue eye and one brown eye.
* Lord Darcia of ''[[
* Watanuki in ''[[
* [[CLAMP]] loves this trope. In ''[[X 1999]]'', Subaru has one green eye and one brown eye {{spoiler|that once belonged to Seishirou.}} While not technically heterochromia, Seishirou has a blank white glass eye that produces the same air of mystery.
** These characters are from ''[[Tokyo Babylon]]'' and there is a detailed reason as for why there are like this. Still count.
* In ''[[Yami no Matsuei]]'', gate keepers can be identified by their different colored eyes. Wakaba has an orange right eye and a brown left eye.
* The ''[[Yu-Gi-Oh!]]'' villain Dartz has one [[Eyes of Gold|golden eye]] (his natural eye color) and one that was turned pale blue by the whole Orichalcos incident. And, if false eyes count, let's not forget Maximillion Pegasus, who has one brown eye and one [[Artifact of Doom|Millennium Eye]].
* ''[[Yu-Gi-Oh! GX]]'': Yubel has one orange eye and one green eye. In Season 4, after Judai merges with Yubel, his normally brown eyes change to these when using his newly acquired [[Green Lantern Ring]] powers.
* ''[[Yu-Gi-Oh ZEXAL]]'' has Kaito Tenjo, whose eyes are silver. When he duels however, his left eye turns crimson. His eye colors are reflected in the colorations of his "Numbers" cards, Number 10: White Knight Illuminator and Number 20: Gig-Anto Brili-Ant.
* In the manga ''Enchanter'' by Izumi Kawachi, if you become an enchanter, one of your eyes changes, turning deep red with a pinpoint pupil. Oddly, long-time friends [[Unusually Uninteresting Sight|don't seem to notice the change]].
* Yakumo in ''[[Psychic Detective Yakumo]]'' has one normal brown eye and one red eye which he usually conceals with a colored contact lens. The red eye can see the spirits of the dead.
* Sasha in ''[[Blassreiter]]'''s final episode had them.
* In the [[Distant Finale]] of ''[[Gurren Lagann]]'', Simon has developed one spiral-shaped eye similar to Lord Genome's, likely to convey that he has mastered Spiral Energy.
* The smug womanizer former monk Julio Cesare from ''[[
* In ''[[
* In ''[[
== [[Comic Books]] ==
* Delirium of The Endless, from ''[[The Sandman]]''. It's part of her overall chaotic look. This disappears when she pulls herself together to be serious. She hates doing this as it is hinted it actually causes her physical pain.
** Both lampshaded and subverted, as one line specifically states she can't remember which eye is supposed to be green and which one blue with sparkles. If you watch carefully, they do reverse from time to time.
*** It's the ''green'' eye that's initially stated to have silver flecks. But she has trouble remembering which one the flecks go in as well.
*** At one point, after realizing she can't remember which eye the flecks are in, they ''aren't'' in her eyes for the rest of the story.
* The new 3D Man of [[Marvel Comics]] acquires red and green eyes to replace Skrull-detecting shades during ''[[Secret Invasion]]''.
* In the Post-[[Zero Hour]] [[Continuity Reboot]] of ''[[Legion of Super-Heroes (
* Nicodemus West in ''[[Doctor Strange]]: The Oath'' has one brown eye and one blue.
== [[Fan Works]] ==
* After her astral body's left eye is damaged/destroyed during the battle in Hell in [https://www.fanfiction.net/s/179718/5/Ranma-and-Akane-A-Love-Story chapter 5] of Eric Hallstrom's epic ''[[Ranma and Akane: A Love Story]]'', Akane Tendo's actual left eye becomes solid black with swirling clouds of red and gold -- and sometimes flashes entirely metallic gold.
==
* Hiroyuki Morita's ''[[The Cat Returns]]''
* A nonhuman/humanlike appearance example: in Shane Acker's ''[[
* Brother Aidan's cat Pangur Ban from ''[[The Secret of Kells]]'', who has one blue eye and one green eye. The viewer may be interested to know that Aisling of [[The Fair Folk]] has green eyes, and human Brendan has blue.
* Tank from ''[[
* In ''[[28 Weeks Later]]'', the mother and her son have heterochromia. When she becomes a vector for [[The Virus]], it serves as a clue to her and her son's shared biological resistance to the [[Zombie Apocalypse|virus]], and an indicator of when they become exposed but remain unturned: one eye becomes bloodshot like a normal <s> zombie's</s> [[Not Using the Z Word|infected]] would, the other remains clear.
* ''[[X2: X-Men United]]'': Jason Stryker has differently-colored eyes, as does the illusory little girl he creates.
** In ''[[X-Men: First Class]]'' Charles Xavier flirts with a (normal human) co-ed with one bright green eye and one blue eye. His jealous shape-shifting pal Raven AKA Mystique alters one of her "brown" eyes to [[Eyes of Gold|golden yellow]].
* ''Supernova'': A device meant to protect a single user from the stresses of light-speed travel is used by the two main characters despite warnings that such misuse can result in a merged [[Body Horror]]. (The others were busted.) Of course, that'd have been a ''major'' [[Downer Ending]], so only some minor merging takes place, resulting in their exchanging an eye, each now having one blue and one brown.
* ''[[Demolition Man]]'' gives the villain Simon Phoenix these. He also has non-natural hair, which fits in with the near comic-book nature of the film.
* Max Zorin in ''[[A View to
* In ''[[
{{quote|
* In ''The Unborn'', the 2009 film, this trope is one of the indications that the protagonist is being haunted by the title unborn twin brother who is trying to possess her.
* In ''Vicky Cristina Barcelona'', Maria Elena ([[
* Brad Dourif's Wormtongue in ''[[The Lord of the Rings (
* In ''[[Practical Magic]]'', young Sally Owens cast a love spell for a man she thinks can't exist, by giving him very uncommon traits. One of these is that he'd have "one green eye, and one blue". Twenty years later, guess what color eyes Detective Hallet has?
* The film ''Redwood Curtain'', based on the play by Lanford Wilson. (See "theater" section below.)
* In ''[[District 9]]'' {{spoiler|the iris of Wikus' left eye turns gold (and huge) at around the seventy-second hour of his transformation into a Prawn.}}
* In ''[[Don't Look Back (
== [[Literature]] ==
* Chip, the hero of Ira Levin's novel ''[[This Perfect Day]]'', has one brown and one green eye. This causes him some embarrassment, since he lives in a world where genetic engineering and restrictions on who may reproduce have produced a world of near-identical people, all of whom have brown eyes. He eventually has the green eye replaced by a brown one, as part of a scheme to lull the [[Big Bad]] into thinking he was finally accepting his role in society.
* Tyrion Lannister in ''[[A Song of Ice and Fire]]'' has, in addition to several other congenital defects, either heterochromia or partial aniridia, with one green eye and one black one.
** Also, the minor character Shiera Seastar had one green and one blue eye, from the Dunk & Egg novels set in the same 'verse.
* ''[[Discworld]]'':
** In ''[[Hogfather]]'', the most distinguishing trait of the [[Psycho for Hire|unhinged assassin]] Jonathan Teatime is his mismatched eyes: one has been replaced by a grey (black in [[The Film of the Book]]) [[Eyepatch of Power|glass eye]], and the other is yellow-white with a pinpoint pupil.
** Just so you realize how [[Ax Crazy]] Teatime really is, in a world where magic <s> has costs and often goes haywire</s> ''is the equivalent of nuclear weapons'', he ''stuck a magical eyeball into his own head''.
** Nanny Ogg's cat, Greebo, also has mismatched eyes, one's a normal yellow cat's eye, and the other is pearly white and blind, presumably due to one of the many fights he's had with animals much bigger than him.
* ''[[Star Wars]]'' [[Expanded Universe]]: Gaeriel Captison has mismatched eyes. They're constantly referred to in the book in which she's Luke's [[Love Interest]], possibly indicating that Luke finds this an attractive feature. As does villainess Ysanne Isard, main antagonist of the ''[[X Wing Series|X-Wing]]'' books. The right is [[Icy Blue Eyes|blue]], and the left is [[Red Eyes, Take Warning]]. They're often [[Evil Eye|symbolically attached]] to the cold efficiency (her nickname is Iceheart) and fiery anger she's known for.
** Gaeriel's daughter, Malizna, inherits the eye colors. Whether this has to do with genetics, [[The Force]], or simple [[Rule of Cool|coolness]] isn't really clear.
* The titular cat in ''Jon, Flora and the Odd-eyed Cat'' (pink and blue).
* [[The Chosen One]] in the old fantasy magazine series ''[[The Ancestral Trail]]'' had one green and one grey eye. The green eye saw only good, the grey eye only evil.
* Candy Quackenbush from ''[[
* In the ''[[
* At the end of the fifth ''[[
** Interestingly, two books prior in The Eternity Code, Artemis has this because of an iris cam.
* In one ''[[Flashman]]'' novel, the fairly nasty Russian villain Nicholas Pavlovich Ignatiev has one blue eye and one eye which is half-blue and half-brown. Notably, Ignatiev is an actual historical figure, but his eye colour is not recorded in history, allowing the author to take a few liberties.
** As an allusion to this, the villain of [[The Peshawar Lancers]], one Count Ignatieff, has a blue eye and a brown eye.
* In the book ''[[The Wild Road]]'' one of the characters, Mousebreath, is a male Tortoiseshell cat with an orange eye and a blue eye.
* In Sarah Monette's ''[[
* The horribly inbred Martense clan from ''The Lurking Fear'' by [[
* In Kristin Cashore's ''[[Graceling]]'', all "Gracelings" have this as a distinguishing characteristic. It becomes important to the plot when you find out that {{spoiler|one of the kings is missing an eye, and it later turns out that he is Graced with a very effective version of [[Charm Person]], as it can work even second- and third-hand, via rumors}}.
* The [[Known Space]] novel ''Juggler of Worlds'' by Larry Niven and Edward M. Lerner reveals for the first time that Nessus, whom Niven created 41 years previously, has one red eye and one yellow eye. (Being a Pierson's Puppeteer, he has two heads with one eye each.)
* All the clone "shatterlings" of Gentian Line in "House of Suns" by [[Alastair Reynolds]] have one green eye and the other a "wintery jackdaw blue", since they're all [[Opposite
* In the [[Matthew Reilly]] novel ''Scarecrow'', [[Big Bad|Jonathon Killian]] has a green and a brown eye.
* Morzan in the ''[[Inheritance Cycle]].'' Though he doesn't appear in the books, Jeod describes him as having one blue eye and one black one, in a similar case to that of Tyrion Lannister mentioned above.
* In ''[[The Master and Margarita]]'', Bulgakov's novel, [[Satan|Woland]]'s left eye is green, and right is black. Justified because he appears differently for different people, but always has abnormalities.
** This aspect was omitted in the 2005 TV adaptation. Cue [[They Changed It, Now It Sucks|the outcry]]...
* The evil sorceress Xayide has one red eye and one green in ''[[The Neverending Story (
* Evil Diogenes Pendergast from the Agent Pendergast novels by Doug Preston and Lincoln Child, has one hazel eye and one pale blue eye. It's revealed late in the series that pigment loss in the blue eye is due to an injury which blinded him.
* One ''[[Goosebumps]]'' book has the main character's best friend be a girl with
* In the [[Roger Zelazny]] book ''This Immortal'', protagonist narrator Conrad Nomikos has
{{quote|
* In the ''[[Keys to
* Giulia in Mika Waltari's ''The Wanderer'' has different-coloured eyes. She's an evil bitch, though, like most female characters written by Waltari.
* In Nancy Springer's ''I am Morgan Le Fay'', the titular character has one violet eye and one emerald green one, which marks Morgan as a fay. They're also described as very dark, so people actually have to look right into her eyes to see the difference.
* In Julia Golding's [[Companions Quartet]], several of the main characters have mismatched eyes, including Connie, the heroine (green and brown), her best friend Col (again, green and brown), and the villain Kullervo (green and gold)
* In Jean Kerr's play ''King of Hearts'':
{{quote|
'''Larry:''' You're kidding. Good God, they ''are'' different!
'''Dunreath:''' ''(defensively)'' Well, it's not a disease! }}
* In Quinn Fawcett's Mycroft Holmes novels, Paterson Erskine Guthrie, Mycroft's secretary and amanuensis, has mismatched eyes.
* "Mirror twins" Eleda and Adele in ''The Truth-Teller's Tale'' by Sharon Shinn have these. [[Secret Keeper|Adele]] has a left blue eye and right green eye and [[Can Not Tell a Lie|Eleda]] has a left green eye and right blue eye.
* In Jostein Gaarder's philosophical novel ''[[Maya]]'', the character Laura has one brown eye and one green eye. The narrator thinks of this as somehow connected to her dual nature - one side of her seems to care for all living things and the planet as a whole, while the other side seems to care about everything in the world except human beings.
* Hnick from Dmitri Yemets's book series ''Methodius Buslaev'' has one blue eye and one black eye according to book 3. Romasjusik is also described as having one golden eye and one orange eye. Both cases aren't natural, since the latter has artificial body, while former's body [[Nightmare Fuel|is stitched from at last two different corpses.]]
== [[Live-Action TV]] ==
* In ''[[Babylon 5]]''{{'}}s later seasons, G'Kar loses an eye {{spoiler|to Centauri torture}}; when he receives the replacement, it is blue instead of red (due to supply shortages), giving him no end of consternation and a singularly unbalancing countenance. He's quite relieved when a second replacement, of the right color, arrives.
* Chief Inspector Derek Conway in ''[[The Bill]]'' had this condition, mainly because the actor who played him did as well (and they didn't want to bother mucking about with contact lenses trying to make his eyes the same colour).
* In one chapter of ''[[Goosebumps]]'' TV adaptation, there is a girl, best friend of the protagonist of that episode who has different coloured eyes, one blue and one in a darker greenish tone. That's because {{spoiler|she is in fact a huskie dog, and all the kids in town, protagonist included, were puppies genetically modified to become human}}.
* Lieutenant Aiden Ford of ''[[Stargate Atlantis]]'' has one eye turn completely black due to an accident during a Wraith attack on the city. This same accident also got him hopped up on and addicted to [[Psycho Serum|Wraith enzyme]], causing him to go AWOL and hunt down the Wraith on his own.
* The 1999 ITV miniseries adaptation of ''[[Oliver Twist]]'' gave Edward "Monks" Leeford one brown eye and one blue eye. Funnily enough he was played by [[Marc Warren]], who went on to play Jonathan Teatime
* From ''[[CSI]]'', {{spoiler|Lady Heather's daughter has one brown and one blue eye. This becomes a horrific plot point when the daughter becomes a victim of an insane Mengele wannabe who prefers his women with two blue eyes.}}
** "Ian Moone", a recent{{when}} villain on the series, has one blue and one brown eye. In this case, it's presumably done to make him recognizable to the audience, as he wears a skin-tight bodysuit and full-face mask.
* ''[[Samurai Sentai Shinkenger]]'', episode 43, features this and [[Red Eyes, Take Warning]] with Fuwa Juzo, the half-monster semi-villain. Can be seen at 6:24 [http://www.youtube.com/watch?v=yDeNEHtftrQ here.]
* The Chief in ''[[Halfway Across the Galaxy
* ''[[Luther]]''. Alice Morgan puts in a single colored contact lens when carrying out her [[Sickbed Slaying]], presumably so the police officer she speaks face-to-face with will remember this unusual detail rather than her actual features.
* Agent Kensi Blye on ''[[NCIS: Los Angeles]]'' has one dark brown eye and one hazel eye.
== [[Music]] ==
* Murdoc Niccals of the virtual band [[Gorillaz]] has two different colored eyes, one black and one red.
** 2D temporarily had this during his coma year, as one eye was normal and the other fully black due to a fracture.
* [[David Bowie]] has a permanently dilated pupil in his left eye, the result of being in a fight, that gives him the appearance of having two different colored eyes, making one look to be darker (sometimes dark blue, sometimes brown) than the other. For a clear view, look closely at the cover of '[
* [[Marilyn Manson]] sometimes wears non-matching contact lenses to ''look'' as if his eyes don't match.
* Tim Mc'Ilrath, vocalist of [[Rise Against]], has those too. [https://web.archive.org/web/20130717142703/http://www.tkbbblog.com/wp-content/uploads/2009/03/tim_mcilrath.jpg One brown, and one blue.]
* The [[Vocaloid|UTAU]] Yokune Ruko has one red eye and one blue eye.
** [[Vocaloid|Utatane Piko]] has one blue eye and one green eye.
== [[Professional Wrestling]] ==
* [[World Wrestling Entertainment|WWE]] wrestler [[Kane (wrestling)|Kane]] has one light-blue eye and one brown eye, with the pupils being slightly different sizes (an effect achieved by the wrestler wearing non-matching contacts, like [[Marilyn Manson]]). Early in his run, it was implied that the blue eye was actually damaged by the fire which had "scarred" him, and that he was blind in that eye. Note to the WWE brain-trust: even we wrestling fans realize that eye color does not work that way.
** Actually, the original implication wasn't that the fire caused Kane's eye to become miscolored, but that it was a ''false'' eye altogether, implying that not only had Kane lost ''sight'' in that eye, he physically lost the ''eye'' as well. This was ignored as the years went on, and now the mismatched eyes aren't even commented on at all, but because it's such a well known feature of the character, it has remained despite no longer even seeming to matter in [[Continuity Snarl|the character's admittedly screwed up history.]]
==
* In the world of Marus, as depicted in ''[[Adventures in Odyssey]]'''s ''Passages'' tie-in episode, different-colored eyes are recognized as a sign of prophecy. Interworldly interloper Alice physically goes from having brown eyes to blue and green, then loses them again when her time as [[God|The Unseen One]]'s messenger is up.
== [[Tabletop Games]] ==
* Shelyn, the Goddess of love and beauty in ''[[Pathfinder]]'' sometimes appears with one blue eye and one silver eye.
* Valerie Rose from the ''Fantasy Strike'' games (''Flash Duel'', ''Puzzle Strike'' and ''Yomi'') has one blue eye and one green eye, and is
* In ''[[Yu-Gi-Oh! (Tabletop Game)|Yu-Gi-Oh!]]'', the Lady of Lament archetype is a small (four monsters) group of female Fiend-Type monsters (Alice, Lilith, Loris, and Malice), and all of them except Loris have this feature, one green eye and one red eye with a black sclera.
== [[Theatre]] ==
* The play ''Redwood Curtain'' is centered on a young Vietnamese girl who was adopted by an American family. She has "eyes like a husky dog" (one blue, one dark). When she meets a homeless Vietnam vet who has similar eyes, she starts wondering if he could be her biological father. {{spoiler|He's not, but he knows who is.}}
== [[Video Games]] ==
* In ''[[Quintessence]]: The Blighted Venom'', Kardian (Alden) performs an operation on Lunair using Reivier's eye to cause her right eye to turn green whenever Shanti takes control, as a warning.
* An updated artwork of Louis Cyphre from ''[[Shin Megami Tensei II]]'' shows that he has a red pupil on the right, and blue on the left to indicate that he's no he.
* Yuna from ''[[
* Marx from ''[[Kirby Super Star]]'' is frequently depicted in fan art as having one blue eye and one red eye, either matching or opposite the blue and red sides of his hat. However, in the official artwork and sprites, both of his eyes are [[Purple Eyes]].
* In ''[[
* The vampire sisters in ''[[Castlevania]]: [[Castlevania: Portrait of Ruin|Portrait Of Ruin]]'' have heterochromia to indicate they aren't full vampires yet.
* Lady and Arkham from ''[[Devil May Cry]] 3'' have heterochromia. It doesn't actually mean anything... {{spoiler|but it serves as an early clue that they're father and daughter.}}
** It also serves as a visual hint that {{spoiler|Arkham is Jester}}.
* Katina Tarask in ''[[Super Robot Wars Original Generation]]''. As of yet, no significance has been attributed to her character, but the fact that she was the winning design of a fan-submission contest may be explanation enough.
** Levi Tolar, on-again off-again [[The Dragon|Dragon]], originally from ''[[Super Robot Wars]] Alpha'', has one [[Red Eyes, Take Warning|red]] and one [[Eyes of Gold|golden]] eye, to match her mecha Judecca. Her eye color changes fairly regularly though, depending on game and {{spoiler|whether her [[Super
* Bitores Mendez, the village chief from ''[[Resident Evil 4]]'', sports one blue eye and one red. The red eye is a falsie, though.
* In ''[[Fallout]]'', Dogmeat has one blue eye and one brown.
* Ballos from ''[[
** The Demon Crown has one eye set in it, that is the same color as his remaining red eye. Fanon suggests that he set one of his eyes in his crown.
* The GUN Commander from ''[[Shadow the Hedgehog]]'', during the game's events and during flashbacks.
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** I always assumed it was a nice touch by the artist due to the fact that heterochromia is common in real life cats.
** Also from the ''[[Fire Emblem]]'' games is Idoun one of the enemies in the 6th game, who has a red eye and a green eye. (It might actually be blue, but with sprites it's a bit difficult to tell.)
* Dr. Loboto from ''[[
** ''[[
* Honoka Kawai from ''[[Osu! Tatakae! Ouendan]] 2'' has a green right eye and a gray left eye.
* Michel from ''[[Pop'n
* It's possible to create Orc and Goblin characters with
* Yuber in ''[[Suikoden III]]'' has one red eye and one silver one. He's also not human.
* Ragna the Bloodedge of ''[[
* Kogasa Tatara in ''[[Touhou|Undefined Fantastic Object]]'', as a humanoid version of a karakasa (a one-eyed one-legged demonic umbrella) has one red and one eye the same color as her hair and outfit, as an alternative to merely giving her one eye.[[The Woobie|It adds to her]] [[Moe]] [[The Woobie|factors, maybe.]]
* The Iris twins from ''[[Rune Factory]] Frontier'', just like Souseiseki and Suiseiseki, have opposite-color heterochromia.
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* In ''[[Call of Duty|Modern Warfare 2]]'', the [[Big Bad]] ({{spoiler|[[The Dragon|or]] [[Unwitting Pawn|not]]}}) Vladimir Makarov has one green eye and one blue eye.
* In the ''[[Soul Series]]'', Zasalamel has one normal-colored eye and one golden eye, possibly as a result of his immortality curse.
* [[Everyone Calls Him "Barkeep"|The Wizard]] in ''[[Harvest Moon]]: Animal Parade'' has one [[Eyes of Gold|gold]] eye and one green eye.
* Atsuki from ''[[Lux
* ''[[Mass Effect 2]]'''s DLC has Zaeed Messani, who has one brown eye and one pale grey eye. The paler eye is implied to be a cybernetic replacement installed after he survived a shot to the face.
* Dr Betruger from ''[[Doom]]'' 3 has one eye that is not only a different colour, but has no pupil. Creepy, eh?
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** He has one normal eye and one chameleon eye.
* In ''[[Deadly Premonition]]'', {{spoiler|Zach}} is eventually revealed to have different-colored eyes, his left eye having been damaged in a childhood trauma.
* In Ragnarok Online, the pope of Arunafeltz {{spoiler|and her twin brother}} has opposite-color heterochromia. Apparently, this was one of the reasons she was chosen as pope. The other reasons was her hair and skin color.
* The main character in ''[[Homura]]'' has these in order to symbolise his half-human half-angel blood.
* {{spoiler|The Masked Man}} of ''[[
* ''[[Resonance of Fate]]'' allows players to change the colors of the main characters' eyes individually, thus creating quite a few options for mismatched eyes.
* ''[[Puyo Puyo]]'' has Sig, who has one red eye and one blue eye.
* There's a few examples in ''[[Vampire: The Masquerade Bloodlines]]''. The Voermen sisters have blue and green, Mister Ox has grey and amber, and the Malkavian and Nosferatu PCs have blue and brown.
* In ''[[
* Vanessa of ''[[Luminous Arc]]'' has one grey/purple eye and one red one, but this doesn't seem to indicate anything beyond being just as loud and noticeable as the rest of her.
* GLaDOS from ''[[Portal (
* Ironhead from ''[[Swim Ikachan]]'' has a right red eye and a blue left eye, although you couldn't tell the latter's colour in his [[The Cameo|cameo appearance]] in ''[[Vieo Game/Cave Story|Cave Story]]'', since it can only be seen when he's facing left.
* Johnny Powell in ''[[The Darkness (
== [[Visual Novels]] ==
* Mary's normally blue eye right turned to gold six months before the story started in ''[[
== [[Web Comics]] ==
* Mannick from ''[[Charby the Vampirate]]'' has a red right eye, and grey (blue in some comics) left eye. It doesn't appear to mean anything in particular.
* Sifris from ''[[Pink Black]]'' has a blue eye and a pink eye. This is never really noted or explained, so it is possibly normal.
* Topaz from ''[[Monsterful]]''; she has a two shades of the actual gemstone her name refers to, her left eye is light yellow and her right one is sky blue.
* Ashley Freyja of ''[[Cry Havoc]]'' has one blue eye and one green, and while never actually mismatched, the werewolves eyes fluctuate between their natural color and yellow when angry or excited. Psychers eyes glow blue when they are using their powers.
* ''[[The Cyantian Chronicles]]'': Syris has one yellow and one blue eye.
* Abel from ''[[Dan and
** According to his backstory, it's natural. Although he probably ''does'' think it's cool...
*** [http://www.missmab.com/Demo/Leader14.php Apparently] heterochromia (as well as wings that are both feathered and bat-like) are traits of an old and reclusive clan, though they occasionally appear in members of other clans and it's usually considered a good omen when they do.
* Most of the Val'Sullisin'rune family in ''[[
** In the case of Ash's daughter Faen, the dual personality [[Innocent Blue Eyes|Blue]] = Innocent / [[Purple Eyes|Purple]] = Mysterious or [[Badass]] [https://web.archive.org/web/20111106104225/http://www.drowtales.com/mainarchive.php?order=chapters&id=274 fits].
* Kade from ''[[Eerie Cuties]]'' has a yellow/gold left eye and a blue right eye. Of course, he ''is'' a [[Our Werebeasts Are Different|Werecat]]...
* The chimera boy [http://www.egscomics.com/?date=2005-01-05 Archie] from Ellen's second life dreams in ''[[
* Vladic from ''[[Emergency Exit]]''. This could be normal for his species for all we know...we've never seen both eyes of the only other Merf character.
* Skye from ''[[Far Out There]]'' has one green eye and one purple one. In her case, the difference is quite practical: the purple one has [https://web.archive.org/web/20170923084806/http://faroutthere.smackjeeves.com/comics/1068887/page-166-gosh-where-can-i-get-one/ x-ray vision.]
* Prism from ''[[Flaky Pastry]]'' has one violet eye and one cyan eye.
* ''[[
** It's also been stated that [[Diabolical Mastermind|Lord]] [[Humanoid Abomination|English]]'s eyes are not only mismatched, [[Up to Eleven|they also switch around rapidly]] through the different pool balls to suit his pool motif. During one author-insert [[
** Vriska also has one normal eye and one eye with seven pupils arranged in a hexagon.
* Aria, from ''[[In
* The title character of ''[http://kokiro.comicgenesis.com/ Kokiro]'' has heterochromia ''and wings''.
* Sudoku (Jigsaw's sister) in ''[[Last
* Maureen from ''[[A Modest Destiny]]''. {{spoiler|She hides her blue eye because blue eyes are considered evil. It disappeared though when she had her baby.}}
* [[Perky Female Minion|Tsukiko]] from ''[[The Order of the Stick
** Her slippers also match her eye color. Apparently she's just decided to go with it.
** Real-life game designer Keith Baker also has heterochromia, and is drawn with such when he makes a guest appearance in the prequel novel ''Start of Darkness''.
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* Anibelle from ''[[The Wotch]]'' has one red eye and one green eye. Easiest to see in [http://www.thewotch.com/index.php?epDate=2007-01-24 this filler comic] done by a guest artist, but can easily be seen [http://www.thewotch.com/index.php?epDate=2008-08-12 normally,] too.
** Oddly enough, though, these clearly mismatched eyes weren't present in her appearances prior to that guest comic. Possible case of [[Ascended Fanon]]?
* Wally in ''[[Zebra Girl]]''. One reason for this may be
* Charlie of ''[[The Zombie Hunters]],'' a [[Half
* Kimiko of ''[[Dresden Codak]]'' has one brown natural eye and one blue mechanical eye as of the "Dark Science" arc, though originally her natural eye color was blue and thus the synthetic one matched when it originally showed up.
* Feral from [[Strays]]. His green eye is natural,the red one was caused by something else. Feral, being mute, can't tell us what.
* Berri in ''[[Fiyora Nya]]'' has one red eye and one green eye. Though they apparently change colors due to her other souls.
* In a variant, Lilith/ {{spoiler|Judy}} in ''[[Girl Genius]]'' has eyes that are mismatched in size, due to being a construct. She wears glasses that make them look like they're the same.
* In ''[[Doomsday
* Chev from ''[[Papi Nyang]]'' has one blue/green and one yellow eye.
* [[Continuum (
* ''[[
== [[Web Original]] ==
* Chaz Villette from ''[[Shadow Unit]]'' has one brown eye and one greenish-hazel.
* Achmed the Snake from the ''Rhapsody Chronicles'' has eyes that are not only mismatched in color, but also in size, shape, and quite probably, species. Also, a face that looks like scar tissue, apparently.
* Longhorn ([[Moe Anthropomorphism]] of Windows Vista) of [
* [http://mylifeinblue.comicgenesis.com/d/20021004.html Simon] from ''[[My Life in Blue]]''.
* Hawley Faust from ''[[Survival of the Fittest]]'' has this, though outside of [[Epileptic Trees]] which might be true (most arguing that they symbolize Adam's nature pre-game and post-game) it has no actual significance.
** As does Dominica Shapiro, who was much more dual in nature (displaying both a thoroughly villainous and surprisingly heroic side).
*** In version four, Charlene Norris has one blue and one green eye, while Clio Gabriella has one green and one hazel. Dave Morrison in the same version has a minor form.
* Evolution's Child from ''[[
* Techno-Devil of the ''[[Whateley Universe]]'' has one eye that's a solid red cybernetic implant. He's only ''fourteen''. He's a mutant too, so his other eye doesn't look normal either. In his case, it signifies that he's the son of the notorious supervillain Dr. Diabolik, and darn proud of it.
* Cigarettes the Cat, a creation by John Kricfalusi. Left eye red, right eye blue.
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* In ''[[The Masked Girl]]'', Griffin has one brown-red eye and one blue eye.
* Several characters from ''[[Homestar Runner]]'' such as Marzipan (one of her eyes is larger than the other), Bubs (one blue eye and one black eye), the Poopsmith (one black eye and one white eye), and Hyperactive Strong Sad.
* Neo from ''[[RWBY]]'' is an interesting case, in that she appears to have complete conscious control over her eye color, and ''chooses'' to have one brown eye and one pink eye most of the time. Her "default" eye color appears to be white.
== [[Western Animation]] ==
* Mr. Lee from ''[[Alpha Teens On Machines|A.T.O.M.]]'' spend most of the first season as blue-eyed... then suddenly he appears with different-colored eyes. No one (except viewers) seemed to notice. {{spoiler|And the next thing we know, he's revealed as [[Evil All Along]]. He turns out to be a [[Corrupt Corporate Executive]]. and an [[Evilutionary Biologist]] to boot.}}
* ''[[The Batman]]'s'' version of Tony Zucco (the guy that killed Dick Grayson's parents) actually has a blue right eye, and a brown left eye.
** Gearhead from ''[[The Batman]]'' has the classic green/red combination.
* The main character of Ann Downer's ''Spellkey Trilogy'' has one green eye and one blue (which is a sign of magical power in that world).
* A few characters from [[Steven Spielberg]]-produced Warner Bros. cartoons have one pink eye and one bluish-green eye, namely Dizzy Devil from ''[[
* Dao long Wong in ''[[
* Coldstone in ''[[
* Botanica in ''[[
* Cyborg from ''[[Teen Titans (
* Harry the tomcat from ''[[The Garfield Show]]'' has the red/green combination.
* In ''[[
* Fastidious on ''[[Yin Yang Yo
* Max the cat from ''[[
* Not official, but some fan art depicts Odd of ''[[
* Ned from ''[[Doug]]'' has one [[Black Bead Eyes|black bead eye]] and one round white eye with a black iris.
== [[Real Life]] ==
=== Famous People ===
* [[Alexander the Great]] had heterochromia; one eye was very light blue, the other very dark brown, according to Plutarch.
* Celebrities with heterochromia include [[Dan Aykroyd]], Jane Seymour, [[Mila Kunis]], Kate Bosworth, [[Christopher Walken]], and [[Lee Van Cleef]] (who wore coloured contacts).
* MLB pitcher Max Scherzer (currently{{when}} with the Detroit Tigers) has one blue eye and one brown eye.
* Silent film star Colleen Moore had one blue eye and one brown eye, though with the film stock available at the time, it wasn't very noticeable.
* Mixed Martial Artist Jens "Lil' Evil" Pulver has one blue eye and one green eye.
* [[Shaun of the Dead|Simon]] [[Hot Fuzz|Pegg]] has sectoral heterchromia, with one blue eye and one blue-and-brown eye.
** As does [http://flcenterlitarts.files.wordpress.com/2010/04/elizabeth-berkley.jpg Elizabeth Berkley], her eyes being green with a brown spot on the right eye.
** [http://www.femalecelebritywallpapers.com/wallpapers/Virginia_Madsen/Virginia_MadsenfSht.jpg Virginia Madsen]{{Dead link}} as well, her eyes being green with a brown spot on the left eye.
* ''Too Big To Fail'' author [[wikipedia:Andrew Ross Sorkin|Andrew Ross Sorkin]] has one normal hazel eye and one golden-brown cat-like eye (which looks [[Evil Eye|really unnerving]] on a big HD screen).
* [[Catherine Tate]] has central heterochromia [http://img88.imageshack.us/img88/5360/tateeyes.png as seen in "Turn Left"].
* [[David Bowie]] was often mistaken as having this. In actuallity, one eye was just permanently dilated, after he was punched in the face in a schoolyard fight.
* [[Gracie Allen]] had different colored irises. When TV shifted to color, she retired (leaving [[George Burns]] as a solo act); she felt that it was too distracting/embarrassing to work in color.
===
* This is actually a very common condition in real life. One can be born with it, or one iris may change color as a result of trauma to the eye. Though in the former case, it's more common for the "odd" iris to be only ''partially'' a different color.
* Heterochromia [[wikipedia:Odd-eyed cat|is not particularly rare in domestic cats]].
* Heterochromia of both the one blue eye/one brown eye type and of the single eye with two colors type is actually very common in dogs with the [[wikipedia:Merle (coat colour in dogs)|merle]] color gene. (The two-eyed variety is also reasonably common in non-merles which have the blue-eyed gene, most notably Siberian Huskies and Border Collies.) Most famously, Mike the Dog, a Scottish border collie who stared in the film ''[[Down And Out In Beverly Hills]]'', was well known for having one blue eye and one brown eye.
** [http://img.photobucket.com/albums/v634/GodofPH/PNutty.jpg Or this puppy.]
** Horses are also sometimes possessed of one blue eye and one brown one. This is known as "glass eye" in the horse world and is most often seen with Paint and Appaloosa horses. The trait is also not uncommon among mustangs.
* One blue eye and one brown eye is a frequent (and for many, defining) characteristic of Catahoula Leopard Dogs. Their ancestry is something of a mixed bag.
** Same for Turkish Van cats.
** "Odd-eyed" is the term used for this condition by many animal breeders.
** This is also called "Bi-eyed" for Siberian Huskies, which have been known to have [https://web.archive.org/web/20131227080919/http://siberianhuskypuppiesblog.com/files/Siberian_Husky_copper_bi_eye.jpg one blue eye and one brown eye].
* Artificial heterochromia can result from certain cancer treatments, though this effect is usually temporary.
** It can also result from an overly scarred cornea, causing the light to refract differently in the affected eye. If there is only one part of the eye that is scarred, that part is affected. If the whole cornea is scarred, the whole iris is a different color.
* Animals with chimerism often have [
* Twins tend to be born with heterochromia.
* An episode of "Medical incredible" had an episode that included this. While one could not tell by looking at the boy, if you looked in photographs, he had Mismatched Eyes. His mother thought this was ''very'' strange because it kept showing up in every single photograph, and ''only'' in photographs. Everyone else thought it was just a trick of the light or a camera flaw, but she knew something was up, so she finally insisted that doctors check his eye in case there was something wrong. Turns out, [[Oh Crap|this was because of a rare eye cancer]]. You can rest easily - because they caught it early, they could cure it, and the boy is alive.
* Using colored contacts to fake this has popped up as a short lived fad every now and then since the creation of color contacts. One of the few times it maintained any relatively extended popularity was among [[K-Pop]] artists.
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