Original Life/WMG
Sissy, Charlie's mother, is Neutral Evil.
She seems to not care about her husband's feelings when it comes to cheating on him, she mainly thinks about herself most of the time, and there is a probability that she will try to force Charlie to be straight while acting like she "wants the best for her daughter." In actuality, Sissy wants Charlie to be straight because she's worried about her own image. Did I mention that she is willing to corrupt others if they don't accept her advances?
Everyone's dead but hasn't realized it yet, and they struggle through a purgatory in search of meaning without knowing that's what they're supposed to be doing.
Angelica is a wildcard, she was put there by the Powers That Be in an attempt to challenge their beliefs and stir them to introspection and through it self-realization. But since they're all such shallow people they just see her as a disruption in the mediocrity and eternity they call their lives.
All the odd occurrences are a result of their subconscious minds manifesting characters and events that that show them something about themselves, but they're too shallow and lacking in self-awareness to understand it.
Fisk's purgatory provides him with a family, but also the opportunity to pursue the same occupation his father did. Rather than realizing how his father wronged him and how that shaped his life, Fisk chooses to ignore it in favor of the easy path of murder, wealth, and avoiding responsibility.
Elizabeth's purgatory has her paired to this man who neglects her and minimizes her impact on his life. Rather than realizing that she consistently set herself up for failure and let whatever influence was strongest on her at the time shape her life, which is the lesson she was supposed to learn, she accepts it and convinces herself she's happy that way. Her children are largely manifestations of her own anger towards herself and the world around her, which is why on a subconscious level she loathes them.
Beth and Aron were drifting around on the sailboat as symbolism of how their lives lacked direction and they went wherever the wind was blowing. Aron's leaving the boat represented his desire to find direction (and thus eventually leave purgatory), but it was a false effort since he immediately fell into the first rut he encountered and stayed there, ardently pursuing a career with no spiritual fulfillment for him and a meaningless relationship based on shallow attraction. Purgatory attempted to throw him a curveball with the transexual thing, but rather than be forced into introspection and consideration, Aron dulled his thoughts and simply decided it was meaningless to him, continuing to pursue the relationship as if nothing were different.
Meanwhile, of course, Beth's refusal to leave her boat and her immediately fucking Trixie represents her rededicating herself to the shallow and loveless life she's been living since she first fucked Fisk and accepted a shallow view of relationships as standard. A final abandonment of real emotional attachment, as it were.
Basically, everyone in Better Days died at some point towards the end, and Original Life is the universe attempting to make them come to terms with that while they ardently struggle to avoid doing so.