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== Anime and Manga ==
* This happens to almost every character in ''[[Ayashi no Ceres]]'' whose ten'nyo powers are awakened, aside from the heroine and a few who get killed in other ways before their powers can kill them. It seems like they live longer the stronger their powers are, but actually ''using'' said powers seems to shorten their lifespan considerably.
* As incomplete [[Dhampyr]], the Schiff in ''[[Blood
* Some of the Contractors of ''[[Darker than Black]]'' fall under this. People whose 'Renumeration' is irreversible can only use them a limited number of times. Most notably, this includes the shape-shifter who grows older every time she uses her power, eventually dying from old age because of it, and {{spoiler|Amber, who could reverse or stop time}}, but [[Merlin Sickness|became younger]] every time she used it, eventually [[Ret-Gone|fading from existence altogether]].
** Shion in the second season is typically in a wheelchair due to his remuneration. {{spoiler|He eventually dies from using his power to copy the entire ''planet''.}}
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* In the ''[[Vorkosigan Saga]]'' there's Sgt. Taura, the genetically engineered super-soldier. She has incredible strength and fast reflexes, but was not made to last. She was deliberately engineered to have a short lifespan and die quickly once she started showing serious signs of age. The Fleet doctor has slowed her metabolism and bought her a few more years.
* The dilemma in the book series ''Magic or Madness.'' Either you use your magic and die at a young age (somewhere between your teen years and maybe age 45 at the outside if you're sparing about it, you die when the magic runs out), or you don't use it and go insane.
* A minor superhero in ''Soon I Will Be Invincible'' is mentioned to have undergone this. His powers slowly killed him and drove him insane, driving him to attack his old team-mates, while his previously invisible forcefield
* Andy McGee of [[Stephen King]]'s novel (and later film) ''[[Firestarter]]''. Thanks to mutagenic drugs a government agency dosed him with in the 1960s, he can "push" people to do things he wants them to -- a minor form of [[Mind Control]]. Unfortunately, every time he uses it, it causes minor cerebral hemorrhages in his brain. If he hadn't died of a gunshot at the end of the book, he would no doubt eventually given himself a full-bore stroke using the push.
== Live-Action TV ==
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