Talisman/YMMV

Ending Fatigue: The highly random nature of the game and the many pitfalls that can befall a particular character (death, losing all items/followers, reductions in stats, and random teleportation), some games can run several hours long before a player wins. The game manual even suggests alternate rules for determining who the winner is at the end of a set time limit for players who want to avoid this.
Game Breaker: The Prophetess's ability to draw extra Adventure cards and discard one makes her easily the most powerful character in the game. The Monk's ability to add his Craft to his Strength in combat is also extremely powerful.