Ito Junji no Neko Nikki. Although it's actually more of a funny manga, it has some heartwarming moments too. Find the manga and see by yourself; describing the moments might prompt a "I CAN'T BELIEVE IT" bit.
Smashed has Ogio's backstory reveal that he was rescued by a tribe while hiking in the Amazon, who nursed him back to health and sent him on his way with a jar of special sap. They advised him to eat it without being seen. Considering the reason why, that was good advice.
Junji ito when he's not drawing horror is shown to be a Nice Guy. He talks fondly of his cats, and later mimics being "Spacejammed" (his words) to appear at a virtual convention.
