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== Films -- Live-Action ==
* In ''[[28 Weeks Later]]'', the mother and her son have heterochromia. When she becomes a vector for [[The Virus]], it serves as a clue to her and her son's shared biological resistance to the [[Zombie Apocalypse|virus]], and an indicator of when they become exposed but remain unturned: one eye becomes bloodshot like a normal <s> zombie's</s> [[Not Using the Z Word|infected]] would, the other remains clear.
* ''[[X2: X-
** In ''[[X-Men:
* ''Supernova'': A device meant to protect a single user from the stresses of light-speed travel is used by the two main characters despite warnings that such misuse can result in a merged [[Body Horror]]. (The others were busted.) Of course, that'd have been a ''major'' [[Downer Ending]], so only some minor merging takes place, resulting in their exchanging an eye, each now having one blue and one brown.
* ''[[Demolition Man]]'' gives the villain Simon Phoenix these. He also has non-natural hair, which fits in with the near comic-book nature of the film.
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* In ''[[District 9]]'' {{spoiler|the iris of Wikus' left eye turns gold (and huge) at around the seventy-second hour of his transformation into a Prawn.}}
* In ''[[Don't Look Back (film)|Don't Look Back]]'', the characters' appearances slowly change over the course of the movie. Characters who are midway through their transformations often have mismatched eyes.
== Literature ==
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