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* In ''[[The Space Trilogy]]'' by [[C. S. Lewis|CS Lewis]], Ransom receives a bite on his heel from [[Demonic Possession|the Un-Man]], which never fully heals afterwards. (Shortly thereafter, he receives a bequest that requires him to change his last name to Fisher-King.)
* In ''[[Silmarillion]]'', [[Big Bad|Melkor]] loses the ability to heal wounds after he becomes a full-fledged [[God of Evil]]. The burns from Silmarils and the wound from Fingolfin's stab stay with him.
* ''[[Horus Heresy|False Gods]]'': In [[Graham McNeill]]'s ''[[Warhammer
* ''[[Elantris]]'': Due to a catastrophe that occurred ten years before the start of the novel, the Elantrians do not heal from their wounds, at all. And they're all immortal. Consequently, the city of Elantris is full of piles of undying Elantrians who are too pained or injured to move, [[And I Must Scream|but are still alive]]. Fortunately {{spoiler|the problem gets fixed at the end of the novel}}.
* In ''[[The Hollows]]'' series, demon wounds don't heal if the victim owes the demon but hasn't accepted a mark for repayment.
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== Tabletop Games ==
* ''[[Dungeons
** The "Cursed Blade" spell makes wounds that don't heal unless a Remove Curse spell is cast, and vile damage only can be healed in a hallowed area.
** Clay golems have the ability to inflict a Cursed Wound on you that won't heal normally, resists healing magic and needs Remove Curse cast on it before you can be healed.
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* In ''[[Deadlands]]'', when a person comes back from the dead as a Harrowed, the wound that killed them never heals completely, which is a problem if the killing wound was something readily visible.
* ''[[Vampire: The Requiem]]'' has the Eupraxus [[Prestige Class|bloodline]] of the Daeva clan. Each bloodline has a specialized curse, and for the Eupraxus, it's that the bites they inflict—which can usually be sealed up by a lick with other vampires—will only heal naturally, which means their meals are usually [[Vampire Bites Suck|left bleeding out]] [[Kiss of the Vampire|while in a state of ecstasy]] unless first aid is applied. It also means that those who are Embraced into the bloodline usually has a bite mark that will never heal, which most members cover up with a scarf, bandage, or other accessory.
* ''[[Warhammer
** Roboute Guilliman's body is kept in a [[Stasis Field]] on Ultramar, his mortal wound still visible. Occasionally an excitable pilgrim will swear that the wound is healing, but the Ultramarines dismiss these claims, since, well, [[Stasis Field]].
* ''[[Exalted]]'': Various Charms can do this, the majority of them belonging to the [[Omnicidal Maniac|Abyssals]].
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* Cuts caused by the Spear of Longinus in ''[[Persona 2]]'' would not heal. This unfortunately does in {{spoiler|[[Cool Big Sis|Maya]] }}.
* At the end of ''[[Castlevania]]'' 1, Dracula inflicts wounds that will never heal, just before he is defeated. Cue Castlevania 2, with Simon resummoning Dracula and beating the crap out of him to break the curse.
* ''[[
* Butcher's cleaver in ''[[Diablo]]'' is the same - while it is said that the wounds inflicted by it can't be healed because of infection, you can heal them as much as you like.
* ''[[Final Fantasy XII]]'' has the Virus status effect (also known as Disease.) Taking damage in Virus status lowers your MAX HP as well as your current HP, so to heal this effect, you need a vaccine, casting cleanse or by touching a [[Save Point|Save Crystal]].
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** The wound even remains when he transforms into his Dark Beast Ganon form, and acts as his weak point in the battle. {{spoiler|In the end, Link completes Ganondorf's long overdue execution by impaling him through the wound with the Master Sword. This time the Triforce of Power abandons him.}}
* ''[[Pokémon]]'': The burns inflicted by [[Hell Hound|Houndoom]] never stop hurting and (presumably) never heal. [[Gameplay and Story Segregation|You would never figure this out by playing the game.]]
* ''[[Fire Emblem:
* [[Dawn of War]] Winter Assault: [[Evil Is Hammy|Lord Crull]] invokes the Bloodthirster "By the Wyrm Eye that bleeds in all the dark places. By the wound that never heals!"
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