Ham and Cheese: There have been certain shows (both North American and Anime English dubs) that they are in which they have been considered to be one of the only, if not the only, saving grace in the show. (The SABAN/FUNi dub of Dragon Ball Z back in the 90's is often considered to be a good example of a hackjob dub with good voice acting.)
The Scrappy/Creator's Pet: Scott McCord is in a lot of the recent stuff. However, a lot of the stuff he stars in isn't that good, and his voice is really rather grating.