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* In ''[[Dungeons & Dragons]]'', the classical example is placing [[Bag of Holding]] into a Portable Hole (both are sucked into a rift to the Astral Plane) or vice versa (both are destroyed, everything and everyone around is sucked into the Astral Plane and a gate to another plane is opened).
{{quote|[http://forum.rpg.net/archive/index.php/t-221494.html "If at any time you're the last person standing, with absolutely no way to save us, fling the bag of holding into the portable hole and pray."]}}
*:* Much the same happens with any two "extradimensional interfaces", with specific effect defined by the one undergoing the transformation, i.e. "inner", if applicable. Usually it destroys them both and often does nasty things to everything around as well. AD&D's ''Tome of Magic'' added 3 more - Flatbox always explodes; Warp Marble always safely deactivates, dumping the trapped creature to the Astral Plane (both also do the same when subjected to any form of teleportation); Dimensional Mine does nothing but dumps any extradimensional space in which it's placed into the Astral Plane, which destroys the item creating the pocket, if any - but not the mine ("Hey, guys, I found a cool figurine on the Astral..."). Rulings on non-permanent spells with such effects (Deeppockets, Rope Trick, Extradimensional Pocket, Seclusion) vary.
**::* So of course this was weaponized in various "extradimensional bomb" setups - e.g. [http://www.spelljammer.org/ships/equip/ed_missile.html as described here]. The probable reason why such interactions were not removed as outrageously exploitable is that magical items are very, very expensive and variants created via spells are either inconvenient or temporary and thus limited by the number of high-level spells the offending party can cast in a row.
*:* Another case is a [[Sphere of Destruction|Sphere of Annihilation]] (permanent or created by spell) meeting a planar gate, except the result is somewhat random - they may pass through each other as empty place or interact violently.
**::* A variant of this is described in the ''Elder Evils'' sourcebook. Putting a Sphere of Annihilation into a Well of Many Worlds creates a ''black hole'' - which proceeds to ''[[Apocalypse How|swallow up the entire Material Plane in a matter of minutes]]'' barring divine intervention.
**::* A Sphere of Annihilation on its own should qualify, as it is literally a hole in the continuity of the multiverse.
*:* There is also the incredibly old demon lord ''Pale Night'' who appears as a female humanoid wrapped in a shroud. The shroud is however not part of herself, but Reality's desperate attempt to hide her true form from the rest of the multiverse. She has the ability to shed the shroud for a short moment and having a very strong [[Weirdness Censor]] is the only thing that prevents everyone from being annihilated by trying to make sense of what they saw.
*:* The multi-setting crossover AD&D module ''Die Vecna Die!'' justified the changes between 2nd and 3rd Edition in-universe, as a result of Vecna the lich-god Dividing Reality By Zero when he escaped from ''[[Ravenloft]]'' to ''[[Planescape]]''.
* This is the premise behind the ''Time Spiral'' block/story arc of ''[[Magic: The Gathering]]''. Essentially, all the near-apocalyptic scenarios that Dominaria (the core plane of the multiverse) has been through in the previous arcs have caused the fabric of reality to become unstable, causing rifts between timelines and universes that threaten to destroy all that exists.
* In the ''[[World of Warcraft]]'' [[Trading Card Game]], hitting The Immovable Object (a shield) with The Unstoppable Force (a 2-handed mace) will destroy both objects.
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