Grey's Anatomy/Tear Jerker

Tear Jerkers in Grey's Anatomy include:

End of season two, Denny's death and Izzie curled up next to him on the hospital bed.
Season 3. The 'woman with two uteruses' subplot in the episode "Let The Angels Commit"
"Damage Case", where an intern from a rival hospital causes a car crash and severely injures a pregnant woman, who dies from her injuries. The scene where the intern begs the woman's father to forgive him.
"Into You Like a Train"...

"Can I ask you something? ...Do you believe in heaven?"
"I do... Don't you?"
"...I want to."

End of season 5 where they find out that it was George who was hit by a bus after pushing a girl out of its path and he dies. Or when Meredith and Derek give their hospital wedding to Izzie and Karev.
That episode where Molly from The Unit was guest starring as a patient whose sister thought she was having serious hallucinations about falling in love with a man she met on a cruise and planning to marry him. Her sister did not believe her and kept chalking the halluncinations up to the brain tumor that Molly's had for a while. Derek was the only one who really believed her. Molly has the surgery and she dies but what made this a true tearjerker was when the man actually shows up at Seattle Grace and tells Meredith and Molly's sister that he and Molly really met and fell in love and was going to get married as soon as she got better.
In season 2, Break Through- When Meredith's DNR patient that she intubated by accident dies, she quickly leaves the room and goes to hide in a supply closet to have a quiet little panic attack. Derek, who is currently back with Addison, follows her and manages to calm her down enough for her to choke out, "I.. I can't- I don't- I don't want my mother to die alone!" When you find out later just what kind of hideously abusive childhood Meredith had, the fact that she has any shred of affection for her mother at all, much less to this point, it makes it all the more heartbreaking.
Dear God, the episode where Eric Stoltz's character is executed, along with the storyline about the kid who needed a kidney and would have gotten it from the serial killer had the killer not had surgery. The scene where his mother is getting ready to say goodbye... And one of the final scenes where one of the female doctors broke down in tears, ashamed of herself for earlier trying to stop the surgery on the serial killer so the kid could have his kidney, and starts praying for forgiveness... Damn you, Grey's Anatomy. Just... damn you.
In season 5 there is an episode with a little girl who is terminally ill and there is nothing left they can do for her but her father just keeps on fighting for her and trying to raise money to take her to Mexico and get her some special treatment. Eventually she dies in his arms while he tells her how beautiful Mexico is.
Seeing Charles Percy die in Bailey's arms.
- Dear God most of that season's finale. Bailey crouching in terror under a bed
So many of the scenes between Cristina and Owen in Season Five, but especially the scene when he's having the panic attack and the scene when he's in the shower and describes how his best surgery involved lying on top of a guy to apply pressure to the wounds and slow the bleeding for two hours in order to save him. He tells Cristina that the guy wrote a letter thanking him... and then killed himself.
The bomb episode. Every single moment of it, whether invoking sad tears (when Derek finds out that it's Meredith holding the bomb, followed by his patient promptly flat-lining, almost everyone leaving Meredith alone in the room, or, you know, the bomb going off) or happy ones (Bailey's baby being born and being named after George), the entire episode is made of this trope.
When George's mom comes to the hospital and Callie tells her about Arizona and Sofia.
After a 39 hour day when Meredith goes to answer the door expecting the pizza delivery and it is the social worker holding Zola. "She's yours.".

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