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{{trope|wppage=Mithridatism}}
{{quote|'''Buttercup:''' And to think...all this time [[Poisoned Chalice Switcheroo|it was your cup that was poisoned]].
'''The Man in Black:''' [[Take a Third Option|They were both poisoned.]] [[Crazy Prepared|I spent the last few years]] building up an immunity to iocane powder. |''[[The Princess Bride (film)|The Princess Bride]]''}}
{{quote|''He gathered all the springs to birth
''From the many-venomed earth:
''First a little, thence to more,
''He sampled all her killing store.|A. E. Housman}}
In short, this trope references the development of immunity to a particular drug or poison [[Charles Atlas Superpower|by taking small doses for a long time.]]
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In some cases, the poison builds up and actually turns the poison-proof character into a [[Poisonous Person]].
This can be [[Truth in Television]], or not, depending on the poison in question. For some poisons, the body produces antibodies to clear them from the system; so, with repeated exposure to small amounts, you can build up a level of circulating antibody that grants immunity to a typical dose. However, there are plenty of other poisons that ''don't'' get cleared from the system and simply build up in your tissues until
This trope is officially named '''[[wikipedia:Mithridatism|Mithridatism]]''', after
{{examples}}▼
▲{{examples}}
== Anime & Manga ==
* Killua from ''[[Hunter X Hunter]]'' is immune to virtually all forms of poison due to his family's [[Training From Hell]], and is seen happily downing five cans of laxative-laced juice before the Hunter Exam starts.
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