Empty Eyes

Lack of pupils, and customary light reflection; iris shading goes from the usual radial to gradient; eyelids drop. Yep, this character is suffering from the Empty Eyes trope, a condition denoting that the character is air-headedly distracted, shocked, traumatized, dead, mind controlled, anywhere among those five points, or any combination of the above. This trope is most common in anime, though as of late, it's made its way to western animation. Due to the condition of shock causing the eyes to dilate, realistic live action will never have this unless the producers Did Not Do the Research. Pushed for effect in Break the Cutie scenarios.

Sister trope of Prophet Eyes, and the two may coincide as repeated trauma could give someone a Disability Superpower.

Compare Dull Eyes of Unhappiness, Thousand-Yard Stare, Mind Control Eyes, Heroic BSOD and Angst Coma.

Examples of Empty Eyes include:

Anime and Manga

After the climax of Sailor Moon S, Usagi emerges from her battle with Pharaoh 90 with blank, horrified eyes.
All the dolls in Darker than Black.
Goes along with Angst Coma and some cases of extreme emotional distress in Black Butler.
At Ragnarok: the Animation's climax this happens to Yufa.

Film

In The Stepford Wives, Jessica's robot double was had empty eyes when it was first seen.

Music

"The Exodus", an Evanescence song, mentions in the last verse "So much more dismay in empty eyes."