Family-Unfriendly Aesop/Web Comics

Fans had this strip involving Rikk, Aly and Rumi eating pot-laced brownies. "Don't do drugs, kids, or they might impair your ability to enjoy drugs later in life!"
Sluggy Freelance ends the "Aylee" Story Arc with an Aesop that you should always stand by and trust your friends, even if there's a very real chance they might destroy all life on Earth.
- Alternate interpretation: if you kill people because of what they might do, you become a worse monster.
Boy Meets Boy basically ends with the lesson that people change, friendships don't last, and you'll probably have to settle for second best, because the love of your life simply isn't interested.
And while on the subject of Sandra K. Fuhr, one of the possible endings to Friendly Hostility teaches us that even with the best intentions, you can't force a relationship to last.
Saturday Morning Breakfast Cereal loves these. For example, the hare put in far less effort than the tortoise, but still got second place, which is, you know pretty freaking good.
Misfile tried to give An Aesop about accepting responsibility when the old road was being taken over, but Ash repeatedly points out that his title grants him no obligation to help anyone else and the other racers freely admit that they aren't friends, they just need someone to fight their battles for them. It becomes less about responsibility and more about giving in to peer pressure.