Memetic Sex God: Everybody is gay for Mike Patton, no exceptions.
Nightmare Fuel: He reportedly used no post-processing to achieve the incredibly disturbing, nightmare-inducing voice of The Darkness. Just his voice and a microphone.
The same talent that lets him range from the nasty gurgling of the Boomer to the hair-raising screeching of the Hunter in Left 4 Dead. As well as all the other disturbing zombie noises in the game. And GLaDOS's Anger Core in Portal.
Hell, his music in general can get to this point. Especially in the cases of Fantomas and Maldoror.