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Acquired Poison Immunity: Difference between revisions
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{{trope|wppage=Mithridatism}}
{{quote|'''Buttercup:''' And to think...all this time [[Poisoned Chalice Switcheroo|it was your cup that was poisoned]].
'''The Man in Black:''' [[Take a Third Option|They were both poisoned.]] [[Crazy Prepared|I spent the last few years]] building up an immunity to iocane powder.
|''[[The Princess Bride (film)|The Princess Bride]]''}}
{{quote|''He gathered all the springs to birth
''From the many-venomed earth:
''First a little, thence to more,
''He sampled all her killing store.
|A. E. Housman}}
In short, this trope references the development of immunity to a particular drug or poison [[Charles Atlas Superpower|by taking small doses for a long time.]]
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{{examples}}
== Anime
* Killua from ''[[Hunter X Hunter]]'' is immune to virtually all forms of poison due to his family's [[Training from Hell]], and is seen happily downing five cans of laxative-laced juice before the Hunter Exam starts.
** He's also "immune" to electricity, eventually making various forms of lightning punches, lightning bolts, and literal lightning reflexes part of his powers.
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==
* ''[[Aeon Entelechy Evangelion]]'' combines this with [[Conditioned to Accept Horror]] in Asuka's EVA pilot training, which included controlled desensitizing to anything that causes sanity loss.
* The titular badger in ''[[The Urthblood Saga]]'', [[Badass Abnormal|among his other powers]], has built up an immunity to all but the strongest poisons from this method. One poor ferret who tried to poison him and take over his army learned this the [[Cruel and Unusual Death|hard way...]]
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* In ''[[Thank You for Smoking]]'', terrorists {{spoiler|try to kill the main character by covering him in nicotine patches, which would overwhelm any normal person, and leaving him naked on the lap of the Lincoln Memorial}}. He survives, and recovers fairly quickly, because he'd been chain smoking for years and had built up a [[Blessed with Suck|superhuman tolerance to nicotine.]] Unfortunately (fortunately?) it also means [[Cursed with Awesome|he can never smoke again.]]
* In the 2008 movie ''[[Get Smart (film)|Get Smart]]'', 99 sprays Max with knockout gas. Max says that he developed an immunity to it, then passes out while cursing, "Oh, it's the new stuff!"
* Pat Morita's character in ''[[King Cobra]]'' is a snake handler who regularly injects himself with doses of snake venom to develop immunity. He's able to shrug off getting bitten by the giant snake once, but after getting bitten a few more times, he weakens and dies.
== Literature ==
* The Battle of Wits scene in William Goldman's ''[[The Princess Bride (novel)|The Princess Bride]]''. The Man In Black has just tricked Vizzini into consuming poisoned wine, and reveals to Buttercup that the wine he'd consumed was also poisoned; [[Out-Gambitted|he had developed immunity to the poison via this method]].
* The murderer in the [[Lord Peter Wimsey]] novel ''Strong Poison'' builds up an immunity to arsenic in this way. This does ''not'' work in [[Real Life]]...though the reference books Lord Peter reads really do exist, and they really do [[Blatant Lies|claim it could work]].
* A [[Discworld]] novel or two mentions a food-taster who has ingested so many poisons that he's not only immune to them but can recognise them by taste (very handy). He can also tarnish silver by breathing on it (not so handy).
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