Blood/Trivia

Descended Creator: The Voice (multiplayer announcer) and Tchernobog were voiced by Jason Hall, who was the CEO of Monolith at the time.
Franchise Killer: The middling reception and low sales of Blood II killed any chance at a third game. With Monolith now under the wing of WB Games and Atari apparently uninterested in pursuing any opportunities with the license, attempts at reviving the franchise are unlikely to happen.
Hey, It's That Voice!: Caleb's voice actor Stephan Weyte gave the character the same voice he used for Monolith's earlier platformer, Claw. More generally, he also acted in some of Humongous Entertainment's games, as well as in Fire Emblem: Radiant Dawn and Metroid: Other M. The other Chosen in the second game are voiced by Michael Shapiro (Barney Calhoun and the G-Man) and the woman of a thousand voices, Lani Minella.
Troubled Production: The creation of the first game was fraught with difficulties. The development team had a number of inexperienced members and was given only a small budget, which left the team struggling for funding. The Build engine the game was being designed for was still being worked on and left the team working with both a game engine and tools that were incomplete through much of development. Assets and source code from an early build of the game were stolen from a PC left in a computer repair shop and posted online, which led to a lawsuit that Monolith settled out of court. Executive Meddling and Creative Differences with 3D Realms led to Monolith splitting from them and signing up with GT Interactive to publish the game. The fact that the game was finished let alone a success under such conditions is regarded as an extraordinary accomplishment by the team.