Vampire: The Requiem/YMMV

Funny Aneurysm Moment: One of the books, trying to encourage STs to emphasize the Darker and Edgier elements of WoD, pointed out how low New Orleans is below sea level, and how unstable the WoD-versions of the levies would be, what with it being a Crapsack World and all. Cue Hurricane Katrina...
- Which is explored in Pandora's Book, which suggests a few ways for crossover-interested Storytellers to work with post-Katrina New Orleans.
- The clanbooks also have a running narrative involving a wave of nightmares being spawned by the destruction of several vampires during the storm, as well as a number of very bad things happening to the survivors.
- If it matters, the original supplement's suggested outcomes for such a story were much more positive than how things actually came out.
Funny Moments: In the novel The Marriage Of Virtue And Viciousness, an elder speaks of what he's learned from talk radio:

"I’ve learned that even our malignance and evil has been surpassed by some mortal sect calling themselves ‘Democrats.’"

Heartwarming Moments: The opening fiction for Ghouls is the story of a beaten and broken ghoul being teased viciously by his regnant, the stereotypical female vampire (withholding blood, doing torture, withholding sex, etc). After a look into his thoughts about his life and times with her, the ghoul begins to think about betraying her by trapping her in a room exposed to sunlight. Cue the Kindred's appearance: someone seems to have already tried to do that to her. Now she's beaten and broken as well, and then she begins to call on her loyal ghoul for help seeking shelter while regenerating her immortal wounds. He does, completely discarding his treacherous plan.
- At the end of Gangrel, Alice drains her nephew Little Jack dry, then, in despair, Embraces him. The story is continued in Nosferatu.
- See You Are Worth Hell.
Idiot Plot: The following is either an incredibly good (bad) example of an idiot plot, or the horrors created by the greatest Kindred Chessmaster of all: the Ordo Dracul book gives the story of the Azerkatil bloodline's founding as a convoluted plot a mysterious vampire called the Red Sultan engineered. He thought his rival in life, Dracula, had used his strange Coils of the Dragon to become an actual dragon. He also thought it was necessary to create a task force to slay this dragon. The Red Sultan commanded the creation and destruction of multitudes of bloodlines. The rules say it takes a powerful vampire, and a few generations of childer, to create a bloodline, and it seems the Red Sultan was able to sacrifice many of them... He's also still extant. So, either those powerful vampires were all idiots, or the Red Sultan's a Chessmaster.
Jerkass Woobie / The Woobie: Any vaguely sympathetic vampire probably qualifies.
Nightmare Fuel: Goes without saying, though the Nosferatu discipline of Nightmare is, as might be inferred, an excellent example.
- Notably, there's Cymothoa Sanguinaria, a hideous parasite from Wicked Dead. Once it infects a mortal host, it begins usurping control of the body, driving the host to seek out blood. As time passes, the parasite takes full control, leaving the host's consciousness aware but powerless, forced to watch everything the parasite does. And that's not getting into how exactly it spawns... Based off a real-life parasitic isopod, Cymothoa excigua, that commonly replaces fish's tongues.
- And then there's the Strix. When facing off against purposeless demons is the least of your problems with them, shit gets real.
Uncanny Valley: The lower the humanity, the closer a Kindred is to this.