Final Fantasy III/Tear Jerker

Don't tell me that the scene accompanied by "Elia: Maiden of Water" didn't get to you. Better tears, happy tears (or, well, sad since The Journey Is Over) likely accompany the post-game sequence (in the DS version, at least).
This troper remembers playing a fan-translation of the NES version and, being a huge fan of moogles, being heartbroken when he returned to Dorga's house after his death to find all of his servant moogles mourning his death. It's made even worse by the fact that YOU killed him.
Xande's Start of Darkness. You've spent your immortal life apprenticed to a master wizard - no doubt making close friends with the other two apprentices, by the way - and what is your reward for this dedication? One gets phenomenal cosmic powers, and an entire continent, the other becomes the ruler of the world of dreams, and you get... mortality. And they call you evil when you want to keep things the way they were? Xande got painted into the villain corner, plain and simple.
- Basically, they outright killed him.
  - Not before Doga and Unei essentially arranged for their deaths. What's Xande going to think when/if he finds that, essentially, Doga and Unei envied his mortality?
How about King Gorn's death? For weeks, he's been mind-controlled by his Evil Chancellor to set his soldiers against each other and to banish his ten-year-old son Alus from the castle. And the final act in Gigameth's plan? Have Gorn murder Alus in his bed--but the order is too much, and Gorn turns the knife on himself to save his son.
- Doubles as a Crowning Moment of Awesome to me. It takes sheer force of will and Power of Love to overcome a powerful spell like that.
Two Words: A ri a's De ath.