Johnny Optimism

Everything About Fiction You Never Wanted to Know.
"What Doesn't Kill You Makes You Stranger."
Subtitle

Johnny Optimism is a Cut-and-Paste web comic that presents a darkly humorous look at everyday life. It started with a horribly ill, wheel-chair bound boy who is trying to remain optimistic despite his limited chances of survival, whose only true friend is his dog, Lance. It has diversified into showing other cut-and-paste clip art.

Tropes used in Johnny Optimism include:

Girl: I don't have any parents. I'm an orphan.
Johnny: I'm sorry. What happened to them?
Girl: They asked too many questions..

Girl: Hey Johnny, the doctor said you have athletes foot. Do you know what "irony" is?
Johnny: Yeah...your legs.