Genre Savvy/Fan Works - All The Tropes

There's the wacky but surprisingly good House/Zombie Apocalypse fic The Rampant Disease, in which House and Co. invoke every trope in the book -- only some of which end up being true.
Nili's The Lord of the Rings fanfic A Taste of Disaster shows how genre savvy Legolas, Aragorn, Elrond and company get after Aragorn and Legolas have been through a few action/adventure fics. Hilarity Ensues.
Often present in MS Paint Adventures forums, especially in the Fan Adventures. A sample suggestion, explaining what's going on to a new character, is clearly very genre-savvy^{[dead link]}.
In the Teenage Mutant Ninja Turtles fanfic The Long Walk, Michelangelo is pleading with OC Breech Loader to do something for him.

Mikey: "Then you can be my escort tonight before it's too late! You'll do it, right! It's important! I need it! And you love me, so you'll do it! Right!"
Breech: "I never agree to do anything without knowing what it is first. How do I know you're the real Mikey, and not some Dai-Oni possessing his body with the intent of making me promise to do something awful?"

In the Mass Effect Self-Insert Fic Mass Vexations, Author Avatar Art goes through pretty much the entire fic noting the events of the game as they go on. He ends up lampshading just about everything he notices, including making an offhand comment about one of the game's Playing with Syringes examples.
Several characters in Total Drama Battlegrounds, though Heather deserves special mention after seeing Rodney die in one of the virtual reality challenges:

"But see, in every movie that's science-fiction or fantasy or the like, the kid always makes it. This time he didn't, and thus, this queen has broken the unwritten rule for such movies. Even an Asian martial artist cliché or the American commando cliché cannot defeat someone who is breaking the unwritten rules. But as I said, I didn't want to say this out loud, or I'd look weird."

Luminosity: Bella realizes that her life is a Romance Novel. Relying on her status as the protagonist may be part of why she makes some risky decisions.
In Harry Potter and the Methods of Rationality, Harry is a prodigy who spent his childhood a) reading fantasy and sci-fi and b) analyzing everything in sight. He constantly uses his knowledge of literature and archetypes to figure out things that his canon counterpart didn't figure out for years -- for instance, that he's destined to fight Voldemort.
In the My Little Pony: Friendship Is Magic Fanfic "A Rising Light", this is one of main character Mike's defining traits, often crossing over with Deadpan Snarker and occasionally bordering on Leaning on the Fourth Wall.

Mike: "Ponies don't start randomly thinking about this kind of thing unless it's about to become some important plot point in a corny story they're in!"

Calvin and Hobbes: The Series has the titular duo, though in different ways: Calvin knows a lot about sci-fi movies, while Hobbes knows the outcome of pretty much any adventure Calvin drags him along on.
One of the hallmarks of being a resident of Angel Grove in Of Love and Bunnies is that, living amongst Power Rangers for so long, they're used to the weirdness and can predict when strange things will happen and what effects they will have.
Switzerland in the 1983 Doomsday Stories is shown as rather familiar with World War III conventions. And is arguably the first to figure out that Austria's decades-long Hope Spot that Hungary may have survived would not end well. He was right.
Arcanus in the My Little Pony: Friendship Is Magic fanfic Whispers is stated in-universe to have become this by reading a lot. He demonstrates it by lampshading a case of Innocent Innuendo.
- On the flip-side, he also demonstrates Genre Blindness by claiming love and friendship have little merit... in a series built on them.
To some degree, Emma in Astral Journey: It's Complicated is like this as she does address the readers, not only as the narrator but seek in some play-by-play.
Basically, most of the characters including Fusion Gundam in Final Stand of Death, is aware of what's going on ranging from their time on Celebrity Deathmatch, fan-fic is based on, to wanting to see the end.
Michael McCole, the protagonist of the Marvel Cinematic Universe Self-Insert Fic A Twelve Step Program to Omnipotence. He may be stealing tech (and other things) from every source he can so he can survive being a background character in a world that's going to be devastated by Thanos in just a few years, but he's determined that he's not going to fall into the trap of becoming a villain:

Sure I could use my tech and powers (when I get them) to steal money, hell, with what I had right here I could just walk into a bank and punch the vault door straight off its hinges, but that would suck me into a villain narrative.
Before you know it, like clock work I'll be running around in spandex with some ridiculous scheme to steal all the gold in Fort Knox using the cunning power of goldfish, only to be defeated just in time for dinner and locked away yet again, all the while screaming things like 'damn you Spiderman!'.
No, instant ramen will have to do. For now.

Sadly, it doesn't work as he expected.

One of the mercenaries in Coil's employ in the Worm/Luna Varga crossover fic Taylor Varga is black, and for that reason refuses to go first into a dark room from which creepy sounds have emanated: "I've seen this movie, I know what happens to the black guy. Fuck that. Someone else can take point. I'll cover them."