Eye Scream/Web Comics

In Dominic Deegan, when the Infernomancer reveals that the blindfold he's wearing features two very long spikes...
- A later arc has one-time villain Urban Eddie demonstrate how dangerous he's gotten by (thankfully off-panel) pulling one from a underling's head.
This happens a lot in Goblins.
Invoked in Gunnerkrigg Court: to scare Paz, Mort creates an illusory Circus of Fear, where all the mannequins are missing their eyes. Except for the clown, brandishing a rusty saw, who says (in Spanish) "What lovely eyes you have, Paz. Will you give them to me?"
- Zimmy and Diego's eyes are commonly mistaken for no eyes at all when they're really a shadowy sort of blockage which is possibly meant to be from her little Crapsack World.
Grin, the demonic antagonist of Seventy Seas, takes a kunai through the eye, but just laughs it off.
Used to distract Jer'kol by Ariel to allow Kormaril to strike at him in this strip of Drowtales. He got better. His eye did not, and Ariel finished him off the next time he tried to kill her.
Abbey in Gnoph usually goes for the eyes first when fighting, with gory results. Three examples here^{[dead link]}, here^{[dead link]}, and here^{[dead link]}.
8-Bit Theater: "Rock-Paper-Scissors in the eye!"
- Additionally:

Matoya: I'll save you from the gruesome details, but suffice it to say that when a demon comments that he'd like to see things through your eyes, he's not speaking metaphorically.

- And then there's this little gem:

Red Mage: Wait, you murdered your own blind brother?
Black Mage: It would have been cruel to let him live after what I did to his eyes.

This page in Namesake
This Schlock Mercenary strip.
- Eyes are lost pretty often: Aardy, Chisulo (on purpose, no less, by Tagon), and Captain Tagon himself. Nano-surgery and rapid regrowth makes it a non-serious injury, though.
  - Turned into a Crowning Moment of Awesome here (the above probably helped to prepare him for that):

Tagon: * schllluk!* Thank you. Now I have a knife.

Inverted Trope, astonishingly, in this strip of The Adventures of Dr. McNinja.
- What's even more astonishing is that this is not Dan McNinja's first inversion of this trope, nor is it his last.
Order of the Stick
- O-Chul broke out of his cage at an opportune moment and used one of the bars to take revenge on his torturer, Redcloak, by shoving it through his right eye. (Even better, had Redcloak not teleported out of the way first, it seems like O-Chul wasn't going to stop with the eyes...) This parallels Start of Darkness, in which Redcloak's younger brother lost his left eye when paladins attacked their village. While Redcloak can heal said wound, Xykon forbids him from doing so as a reminder of his failure to properly protect his Phylactery.
- It is a bad idea to say "I think there's something in my eye." when Belkar is within (dagger) range.
- Eagle-Eye Pete learned that it was a bad idea to choose a nickname based on something he couldn't afford to lose. Twice.
- Lacking anything else to use as a weapon at the moment, Roy smashes the phial of the healing potion he just chugged down into Thog's eye. Even a raging Barbarian can't shrug off broken glass in the eyes.
Sluggy Freelance: "Keep your eyes peeled." The damage leaves Acey with an Eyepatch of Power.
- Also, apparently Oasis once popped a guy's eye out of its socket and strangled him with his own retinal cord.
- Also Dr. Schlock, here.
While Starslip doesn't explicitly show how Cutter loses his eye, the implication^{[dead link]} is pretty clear.
Done in Dead of Summer to Dr. Light.
Queen of Wands, here:

Grammar Nazi: How are you feeling now, Jimmy?
Jimmy: Like I just fucked Jocasta!

Penny Arcade.
- Not the first time they've done it. Jesus FUCK my EYE CHRIST!
  - Also not the last time.
    - But that would be needlessly unpleasant.
From the Midnight Crew intermission in Homestuck:

Snowman: Hold still Slick. Something in your eye.

- Also, Rose attacks an ogre in the eyes with knitting needles, blinding it. Then uses the yarn as reins and rides it.
  - Her alpha counterpart does the same to Guy Fieri. It's a tad bloodier this time.
- We eventually learn how Terezi was blinded: mind-controlled to sleepwalk outside and stare into the sun until her corneas burned out. Fridge Brilliance: Pyrope means "fire-eyed".
- The way blind Sollux is drawn makes it appear his eye sockets are empty. Just what did Eridan's blast do to him?
Shuugo of Juathuur gets his eyes gouged in a flashback. You can view it in all its gory glory here.
Wapsi Square has this lovely little strip.
String Theory has Dr. Schtein, who had his eyes melted out of his head by a plasma burst in an experiment gone terribly wrong; however, he receives working red-on-black prosthetics. Schtein is still unhappy about his appearance, though.

Schtein: The only thing that happened to me is a plasma arc burnt the front of my face and melted my eyes out of their sockets.

Matt from Murphy's Law fires an arrow into a dragon's eye.
In Chainsawsuit, a man gets a popped champagne cork in the eye here.
Our Little Adventure Example: A female imperial mook the group was fighting in this comic gets shot by Julie in the eye right after this mook lost her arm.
- And in one of the later battles against an Angelo Kid, this magician casted blindness on Angelika. Instead of something traumatic happening to her eyes, they completely disappear from her face.
Poor, poor, Liam. and it was done by the Spy who replaced Gabry, his lover.
Suicide for Hire: A (rather doped-up) man loses an eye after receiving a lap dance by a stripper with implants. No, really.
A Softer World: In this world there are two kinds of people. People like me, with knives, and people like you, with eyeballs.
In Godquest, Galvan has to wear a mask over his eyes because he lost one of them confronting a demon.
The Dragon Doctors has Goro confronting a woman with Eye Beams. Goro is badly hurt in the fight, but proves very handy with a pair of scalpels.
Sequential Art has possibly the cutest Eye Scream ever. Stoopid candee cane.
The Purple Shirted Eye Stabber from Cyanide & Happiness. Subverted in one strip where the guy getting stabbed is a fan and is happy to get his eye stabbed.
In Digger, it's mentioned to be a "kindness" to sew shut the eyes of acolytes who display second sight, possibly so they aren't constantly trying to untangle it from their first sight.
Unicorn Jelly: Eye am not eye!
In Prophecy of the Circle, one of the tekk gets a spear thrust into its eye. We don't see the impact, but the aftermath -- half of the spear's shaft stuck between bloodied eyelids -- isn't too pleasant.
UNA Frontiers: Cyberna is troubled by recurring visions of a woman with gouged eyes, which come from the carried-over memories of the woman whose brain patterns served as her personality template.
Parodied in John And John.